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Post Info TOPIC: HCV/HIV Drug Creation Timelines


Guru

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RE: HCV/HIV Drug Creation Timelines
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Hi Wayne,

Good article. Nice to reminise. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm



Guru

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Thanks for posting this, Wayne, lots of interesting information there.  



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Jill 

(68 yo, lives in UK)

Was Gen 3a, 

24wks Peg/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



Senior Member

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From the American Chemical Society:

"The progress in HCV therapy in the last three years is similar to the progress that took HIV therapy ~14 years.  We are at the brink of approval for an all-oral drug combination that is dosed once daily as a single pill, has >95% efficacy, and is well tolerated.  This article summarizes the path to this success and the challenges still ahead."

http://pubs.acs.org/doi/ipdf/10.1021/ml500070q

 

 

 



__________________

66 y/o male - Geno 1b - F4 cirrhotic dx 2001 - 16 wk treatment w/ Sovaldi/Olysio/Riba - Und @ EOT+24 SVR

 

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