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Hep C Discussion Forum -> Hep C News -> ViralEd Independent Review of the 49th Annual EASL
Post Info TOPIC: ViralEd Independent Review of the 49th Annual EASL
mallani


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RE: ViralEd Independent Review of the 49th Annual EASL
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Hi Wayne,

Good theoretical discussion where price and drug availability are ignored.

It's rather disappointing that how to diagnose cirrhosis is glossed over, when so much of the discussion focuses on the special needs of cirrhotics. Geno 2 and 3 were virtually ignored.

The question of Ribavirin use remains up in the air, and the Geno 1a and 1b differences confused me.

These discussions are worthwhile, but of limited value before FDA approvals and pricing announcements.

Nothing I heard changes my opinion that Geno 1 non-cirrhotics will have ~100% SVR with 12 weeks of Sovaldi/ Ledipasvir, and cirrhotics ideally should have 24 weeks for the same result.

It's good to hear that Sovaldi can be 're-used' for prior Sovaldi failures. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Tig


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Wayne,

There's a rule against posting this kind of information at midnight!  Just kidding!! If I get started on these things late at night, I end up watching them through the end. This one will have to wait til tomorrow! I do appreciate you posting this, looks like it will be a very worthwhile presentation, thank you.

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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OldenSlow


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Lengthy (90 min) but informative eSymposium discussing key data presented at the recently concluded EASL in London. Email address required to view. Topics include various study data (Pearl, Sapphire, Ion, Cosmos and others), treatment of cirrhotics, whether to use riba or not, re-treatment after failure, co-infection and more. Actual discussion begins at 3:30 mark.

Independent Review of 49th EASL

 



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66 y/o male - Geno 1b - F4 cirrhotic dx 2001 - 16 wk treatment w/ Sovaldi/Olysio/Riba - Und @ EOT+24 SVR

 
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