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Hep C Discussion Forum -> Living With Hep C -> Extrahepatic Manifestations of Hep C - Updated Fact Sheet
Post Info TOPIC: Extrahepatic Manifestations of Hep C - Updated Fact Sheet
emilyjones


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Extrahepatic Manifestations of Hep C - Updated Fact Sheet
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Beyond the liver, HCV chronic infection leads to a multifaceted systemic disease. Some extrahepatic manifestations are immune mediated while others seem to be driven by chronic inflammation. Such extrahepatic manifestations should be well known by clinicians.

More Information : Link removed. No pharmaceutical advertisements allowed, sorry!



-- Edited by Tig on Wednesday 26th of June 2019 09:16:46 AM

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Emily
Tig


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Here’s a short article by Lucinda Porter, RN, on higher heart disease risk in patients with HCV. Thanks to Hepmag.com and Ms. Porter for the article.

 

https://www.hepmag.com/blog/hepatitis-c-heart-disease



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Cinnamon Girl


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Hi John.. well yes these health issues do look quite alarming when listed together, but remember that majority of people infected with Hep C won`t get many of these problems, if any at all.  The most common symptom of having Hep C is fatigue but some of these issues that are included occur quite rarely.  I would think that once the virus is cleared and SVR has been achieved then the risk of developing the cancers mentioned here would decrease. 

 

Hi Marsha... I`m fine thanks.. enjoying being out in my garden at this time of year.  I`m particularly fond of my avatar rose, it`s a climber with a very sweet scent. 

 

Thanks Malcolm...that`s a good point and I think sometimes we expect too much too soon post tx and wonder why we haven`t returned to `normal` after being infected with this virus for decades. 


 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
JLynch30


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sounds pretty dire?  Do we still have an increased chance of some of these blood cancers after SVR?



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 
coolheat


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Thanks Jill, very informative. Hope all is well with you, like your avatar. A Sweet Pink.



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65 YO F, GT 1a1b, ast 14 alt 21, fibrosis 3/4 DX 1968 non a or b, TX 12 wks Harvoni, SOT 6.1.15, 1st bld wk: detected unquantifiable EOT 8.28.15 detected unquantifiable, 3 mo.EOT mid Nov.~SVR 12: ) UNDETECTED
mallani


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Hi Jill,

That's a good, complete summary. It's important to realize that some of these extra-hepatic manifestations aren't cured by SVR ,  i.e. there may be permanent damage from the virus.

Most doctors have little experience in these.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Cinnamon Girl


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 A very comprehensive updated fact sheet covering a wide variety of extrahepatic symptoms which can be associated with the Hep C virus.

With thanks to the HCV Advocates website, pdf format...

 

http://hcvadvocate.org/hepatitis/factsheets_pdf/Extrahepatic.pdf



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
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