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Post Info TOPIC: Merck 3682-B for harvoni relapsers


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RE: Merck 3682-B for harvoni relapsers
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Hi Angelseven,

I did 18 weeks with riba way back with Merck's trials in 2013--before Harvoni was approved.  Few side effects and UND at week 4 and since.  I was a happy camper with my trial and Merck still checks me every six months for free.  Only trial back then that would take me at my age plus cirrhosis and diabetes.  Just referred April(other forum) to this site so she could get great info.  Have you made a decision about the trial yet?  Good luck whatever you decide !!!

SuziQ 



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Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR



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Paula at Baylor said one pill a day, i will give her a call... there are others in the trial now and she reports very few side effects if any, i know a gentlement that just finished but he had riba with his... it is in phase two.. i am usually pretty skeptical but my gut feeling is good on this



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62 year old female      1a, f1-2, had virus 40 years   STARTED HARVONI for 8 weeks 11/19/14, relapsed one month after tx  ended in 1/15.  Fibrosis level was only .5 after fibroscan 12/15. Began treatment with Mavyret on January 20, 2018 for 16 weeks!  Ending May 12.



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Greetings.

Looks like 2 pills per day x 24 weeks if no RBV. There are a lot of studies to determine several issues that are considered safety issues.It looks interesting, but pretty early and highly experimental.

Best to you and yours.

 

JimmyK

 



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Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



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https://clinicaltrials.gov/ct2/show/study/NCT02613403  this is the one although she said I will be taking one pill daily??



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62 year old female      1a, f1-2, had virus 40 years   STARTED HARVONI for 8 weeks 11/19/14, relapsed one month after tx  ended in 1/15.  Fibrosis level was only .5 after fibroscan 12/15. Began treatment with Mavyret on January 20, 2018 for 16 weeks!  Ending May 12.



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I am trying to get info on this trial... the gal at Baylor in Houston says I can start in August or September... 24 weeks ...this treatment is a combination of MK 5172, 3682, and 8408.. it is in stage 2.  I believe it is called C-Crest 1, still getting information... apparently there are very few side effects... It is one pill daily... has anyone done any of these Merck drugs without Riba? 

I am happy to get in this trial as I only have catastrophic insurance til I get medicare in 3 years...

Thanks,  Angelseven.. aka,  connie



__________________

62 year old female      1a, f1-2, had virus 40 years   STARTED HARVONI for 8 weeks 11/19/14, relapsed one month after tx  ended in 1/15.  Fibrosis level was only .5 after fibroscan 12/15. Began treatment with Mavyret on January 20, 2018 for 16 weeks!  Ending May 12.

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