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Post Info TOPIC: 2017 HCV New Drugs


Guru

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2017 HCV New Drugs
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Good update.

Too bad the sof/vel/vox trial (Resolve), for GT1a/b relapsers of harvoni or veikira, is only in Maryland! And it may be that this one is already winding down.

Good MK is testing out their NS5A "ruz" (MK-8408), along with their new NS5B (MK-3682), it's just to bad riba is being used to make this a "triplet", but good the trial is in many locations, countries and quite inclusive! I note the name of their new NS5B (MK-3682) is "uprifosbuvir", and uprif is not so "new", it has had other names such as IDX21437. Uprif has been in tortuous development for some time time it appears, first with the company "Idenix" (before some of Idenix's drugs were aquired by MK), and then much wrangling between Gilead and MK has occurred over Idenix/MK drugs, then more talk about overly? stringent trial requirements for the ruz/uprif to be used in a triplet? Oh my. Hm. Nobody said the drug business was easy eh. 

Always good to know what's happening 'round! biggrin



-- Edited by Canuck on Tuesday 7th of March 2017 05:45:32 AM

__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)

Tig


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Recruiting and upcoming hepatitis C clinical trials 

 
The clinical trials listed on this page can be found online at ClinicalTrials.gov. A Web site maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH). This is not a complete list of clinical trials, to find out if a study is enrolling patients in your area please click here

HCV New Drug Trials



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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