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Post Info TOPIC: Started harvoni 5/1/18-my thread :D


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RE: Started harvoni 5/1/18-my thread :D
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ah poop. What a bummer that it was a sinus infection, but so good you are on it, and paying good attention to these things. Too bad you have to do a course of antibiotics (I mean - i would have been so much happier if you had just not had ANY sinus trouble period) but that is the correct right call you and your doc made given the long ongoing symptoms. So is the imaging, she is right to consider further investigation just to see if there is anything else she can know to help prevent further troubles in future - ya never know unless you look, think, consider everything thoroughly. I had a spell of irksome things befall me post-cure - wierd skin things, eye and ear things, facial lumps, bumps and yucky growths - I also had to do some antibiotics of various sorts (oral, drops, ointments, gels, sigh) I just kept growing up new boil like things in my ear canals and one nasty one on my forehead, and had to keep getting them lanced. yuck, the ear things were awful painful, the forehead one was the worst, looked the worst anyway, my eye was crooked awful near swollen shut with it as well, they lanced and packed the forehead one for a while with wet daily dressing changes then slowly we drew the edges together with steri-strips to close it - you can hardly see where it was now. It was not a nice time, but not too serious either, I got over it, but it was a wierd stubborn spell i went through for a while just after cure, I think as my overall health improved post-cure, then so did all these irksome events decrease porportionately. Tig was so right ... at one point, he reminded me I was probably not drinking enough water, even though I was post-cure, and he was right, i had slacked off the water. Water intake is STILL important to me. Now, that is not the case, in your case, cuz you have always been so good in the water department. Maybe this tough long haul was just a little too long a haul for you, maybe you did need a wee bit more rest, maybe that might have helped, who knows, maybe some more time off (if it can be managed), would be a good thing to try. Wouldn't be (in my partners case), for a type A stress-boy personality, that would drive him absolutely bonkers being restricted from anything he wished he could do. Lay low, rest up, do all the things you probably already know what to do to help your sinuses, treat yourself extra good and special in some way. 

Good you had lots of bloods drawn and a repeat AFP, always good to keep an eye on everything, and nice when things just like simple labs help confirm what's up and what's not. Let us know when you know what your bloods say, until then, glad to hear you are napping/resting. Just the thing to do. smile C. 

PS - what kind of antibiotics did you get, how many mg each, how often (1 pill twice per day you said?) and for how long. Had your (inner) ears been "popping, muffled, paining" prior, or at all? Did she say she looked and could see your drums appeared inflammed/involved? Did you discuss anti-histamines or decongestants - hot compressing your neck/ears/eustachian tube areas -increased humidity to breathe? Just nosey.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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i went to my family doctor today and she put me on antibiotics for sinus/ear infection.....and! more time off from work.

i like that i can take it easy and not have to work while my body fights this infection ; work has been way too difficult feeling like this.

after harvoni these meds should be a snap; but i am using my harvoni pill keeper since i have to take these 2 a day together or apart.

she also did lots of blood work, i didn't read it so it will be a surprise but it was 5 vials. also my AFP was done for the liver doc.

the doc says if i have another migraine she wants me to have an mri...... hmmmmmmmm, if it's dye in my veins i doubt it

she's really following how the during and after harvoni stuff goes, she is getting very informed.

ok, nap time for me; looking forward to getting well from this sinus infection

5



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

Tig


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It’s nice to have a caring and considerate employer. That makes treatment and your job, in general, so much easier. Big +1 for that. Home, a nice invigorating and ultimately relaxing shower and some TV down time! Good for you.

I want to comment on the nsaid fog. It’s entirely possible it’s related more to the Hep and the Tx medications. It’s very common and the good news is, after SVR, you should realize great improvements during the first 6 months post Tx. I had moments when it was like a light bulb turned on and I realized I was actually remembering things easier and that odd fuzzy confusion or thought delay had let up. I hope you can enjoy that, I think you will! smile



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i made it 5 hours at work and the boss had mercy on me ,also i didn't get any flack for calling in. she marks it down as part of my harvoni tx..... too cool huh? wow

.....and that is why i try so hard for her

so, the nsaid fog is lifting along with the gut pain from it . and my hope is that it was the new b12, but i do have a mild headache akin to previous sinus problems.... it all seems manageable anyway.

but i came home,showered and plopped in front of the tv biggrin, feeling happy to have things managed so well all around me.

5tth



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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hi tig, wow..... getting one while driving would def scare me too much.

i hope that's the only one i ever get; sure it's pretty and all...but....,well you know

it sounds so complicated when reading about them, but so many ppl get them. of course i googled celebrities with migraines.hahahaha; figure if the show must go on i should find out who's going on.

i feel well enough today; it feels like seasonal allergies and i haven't been able to control those very much.

for now i'm still focused on recovering from my harvoni and cured from hcv, at least there is something that worked for that!

i guess somewhere in the back of my mind i thot the hcv would get me so i kept working and spending money

so now i can revamp to saving cos i am gonna live

ok, off to the insane asylum for a few hours of work....lolol biggrin



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

Tig


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I’m glad you’re feeling better every day, 5! You go girl! I’m sorry to hear about the migraines everyone speaks of. I had some doozies of my own, but thankfully have avoided the bad ones for years. Lucky me! I still have all the precursors to them though, which is weird. I get weekly auras and those damned prism effects. They don’t do much for your forward vision! I’ve had them hit me while driving, that’s a bit unnerving!

I hope you’re enjoying the time off!



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hi canuck,

i def would have panicked if it was as strong as yours....i'm sure of it!

good for me it was at work so everyone knows and want me to feel better.

funny, i had just told my boss a few hours earlier that i was almost feeling as good as before tx except for the tiredness .hahaha.....right!

and i agree, i felt i did want more time to take it easy and my body said "here ya go......." hahahahaconfuse

i only have to work 2 more days then have 3 days off so should be ok..... i'll go to bed earlier tonite and get some good sleep and wake up refreshed.

we had some stress at work during the week, plus i did over do it at home on my 3 days off..... normally no it wouldn't be too much; but on harvoni rehab time it def was.

my next 3 days off will be much easier and i'll make that so.

so cool that you don't work and that's ok with me; i'll take some of that thinking on for me sooner than later i think

yes, will chk BP and at dr's will have labs for b12, thyroid and blood sugars.

i started taking more b12 the past week so of course that is on the shelf for now ; i'm not taking any chances

just water and thyroid for now.

i hope i feel as good as i did friday, but i really haven't been sleeping well so that must add in to all of it.... i was tired after 3 hours of work, but made it till 1am when the lights wanted my attention.

it is def easier to move thru scary stuff with ppl who have walked the road. again, thankyou 5

 



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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I am glad you (and the good minders of your well-being - the body police) have decided you must "assume the position" and stay home, be off work and rest. It is too bad you are still struggling with feeling "better" - but I think it will start coming soon. You just need a break, a more "even keel" spell to see that there IS light at the end of the tunnel - just like STL's avatar! Feeling better is coming - it took me quite some time to start feeling better, but it did come!, sometimes huge little things occured which pleased me no end, and other things were just slow and steady and are still getting better! biggrin This up and down business can unnerve a person, or at least it's very wearing/testing on a body and soul. But just look at what you accomplished!, you worked your way right through treatment. I didn't have to do a gall durn thing, cept get my butt to the doc when he said to, and then I had James do ALL the heavy lifting, NEVER in a million years would I have EVER been able to do what you did and work my way through treatment - you hard workers impress me alright. 

You ask about my area of expertise?? - absolutely nothing, THAT's what I do best!, but for some reason I seem to have very little spare time!, i have always aspired to do as little as possible and up until now i have been very busy and sucessful at it! hahahahah I have tried my hand at a few things, some professionally mostly done very unprofessionally, enjoyed it all, master of none. Love medicine, and still love to read and learn. 

My "migraines" are easy breezy, really, compared to his kind - frequently I get the visual disturbances, but rarely pain, so it's a non-event really - his can get bad, sometimes those 2, 3 day things of wasted down time, until he gets control/rid of it. The first one I ever had was strong tho and scary, lost my balance entirely, double vision so bad I did not know which way was up/true horizon, fell over and could not stand up, mind you it did not last long at all - but hey, YUCK! Glad you tried meds and rest, that was the thing to do. That's a good sign then, an omen, that you found the headache part of it ended up being fairly mild - I bet this IS just a one off, or maybe a sinus influenced thing as you suspect - temporary in nature. If it worries you, don't ignore it, then you should go to the doc, but I think (maybe) you have been pushing yourself just a tiny bit too much with all this working, I know, I know, you felt you could and did and did so carefully, but maybe you did/do need just a little bit more downtime, rest, recoup, relaxing, regenerating time. Consider it still. Maybe that's your bod talking to you saying, "yep, more rest lady, I'm gittin better, on my own timeline, just be patient and treat me even better".

Take your BP for a while (like you did before) just to make sure everything is remaining good on that front. Energy, feeling bagged was a big thing for me, before, during and after treatment - that was the longest thing to resolve. Hang in there and rest, when you feel a wee bit better maaaaybe don't go back to work if you don't have to?, try just booking off for a while and enjoy working on some walks, activities you enjoy, classes of interest, mild exercise programs, stress-free things, good for you/ healthy/ or funner things, which have no big expectations and demands. Possible? Just a thought. winksmile C.

 



-- Edited by Canuck on Sunday 15th of July 2018 03:53:56 AM

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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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thanks canuck, i appreciate your post. i got lucky, even the headache was mild and store bought antiinflamatory worked ok.. advil, took one fourth a pill and it cut it back. as soon as i felt safe enough to see i wasn't having something else i took one half and slept well enough. 

i do hope it's a one time thing too. i do feel tired, drained and kind of sick... so i just stayed in bed today except to eat.

those meds make me feel drained too so hope that's part of it all.

yea, somewhere along the line i learned to think things thru and be more logical than panic too fast........ but i sure was scared

so sorry to hear you and your Mr suffer from these too often. 

i do hope i wake up tomorrow without the fuzzy brain

have a wonderful day, i'm thankful to be at home relaxing and not trying to tough it out a work.

what kind of work do you do?



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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Hey 5!,

Well, that was weird ... about you getting your first and only migraine - I'll say! (understatement) that it must have been (felt) alarming as it came on -  you are a good figurer, or guesser, I suppose that is what i would have ended up guessing too (in the end) migraine perhaps brought on or contributed to by ... some stessors such as ... my, just about anything! But, if i had never had a migraine before, I'm tellin ya, it would have taken me a lot longer (than it did you) to put it all together to come up with a good guess as to what THAT was all about - you did well, to get things thought out and sussed so quickly, a little less mystery, a perhaps leaning to a correct self-diagnosis? ... (long after my first one) I got diagnosed as having migraines without the pain part (lucky eh?!) I just got all the other stuff, aura, visual disturbances/blind spots/growing prisms obscuring field of vision, dizzyness/loss of balance/vertigo. (At least that's what we guess it is that I am doing!) Nowadays, I sometimes do get a headache following the prodromal stuff. My first was quite strong and shocking and profound, and I'll tell you (same as you said) I wouldn't wish for another one like that first one, but all of mine since then I think have been mild if there was anyway to compare to another person's migraine. Just feel very lucky i generally get NO headache with it! My partner gets them bad, his are dif, same prodromal but add nausea, flu-like symptoms, body aches and pains, so ... he always gets optimistically fooled into thinking "maybe" it's NOT a migraine ... (hopeful-like) and then he waits too long to take his meds and often has a longer, harder time to resolve his full out/full blown/well-developed migraine. Sigh. He doesn't get them as often now, as he did in the past tho. The fright of your first migraine you can actually, eventually, become used to (if they persist), once you have recognized what these symptoms might be heralding, and learn how to try to deal with them, they become not so shocking and surprizing - albeit painful, inconvenient and disappointing! For some they are very debilitating, but whether mild or severe we can all learn to deal with them as best we can.

Everybodys' treatment(s) for migraine may be QUITE different - for me, mostly, I do absolutely nothing (really) - but I will always drink more water if I feel a headache (of any kind) coming on. I might take an OTC tylenol at best, but on occasion, if and when necessary, I will take a stronger scripted prostaglandin-type anti-inflammatory/analgesic drug that we have always had a script for and keep in the house, that just happens to work well for everything from menstrual type cramping pains, to even quite severe post-surgical dental pain, and/or happens to work well for fairly severe migraine pain too (we have found)! 

Docs have tried many dif. remedies for my partner over the decades, he has now refined it down to mostly the scripted prostaglandin-type anti-inflammatory/analgesic drugs which he takes in tandem with another anti-emetic/anti-spasmotic type scripted drug, together they potentiate one another and work fairly well, especially if he takes them early enough to help thwart a fullblown migraine.

I hope this migraine was just a one off for you - maybe you are right about sinuses, and perhaps other influences/contributory factors, and, it IS early days in getting over your HCV cure, things may take time to sort and settle as you become more and more the new and better HCV-less you! smilewink C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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it's been 14 days since the last pill [well, 15 by now].

i'm happy to report that i'm actually feeling like myself again... nothing weird happening in my bod or mind now.

it took about the full 2 weeks to get here, i guess the half life is 11-14days, and that makes sense why i still had some weird and new sides.

i still have some energy lack that i'm sure will pick up as the days go by.

God bless the daa's. wow. , and ppl who found them.

and the ppl here on the forum that make it feel like the good thing that it is to get treatment..... i feel so blessed that i found this forum 

5



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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thanks canuck, that is a more peaceful explanation; funny they just off hand call it tumor marker round here.hahahaha.

AFP does sound more benign biggrin

i guess i could never remember afp.... but i will. afp,afp,afp



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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Hey 5,

We hve been talking about AFP's here and here on the site lately ... 

An AFP?? - is a "tumour marker"!?? ewww, now THAT just sounds waaay too scary (and maybe too simple an explanation) - I never call an AFP a "tumour marker" (or at least I do not refer to an AFP, SOLELY as a tumour marker), because it is NOT (just) that!, it is merely a test, a "rough" guide, a possibly very helpful one (when combined with other test results and symptoms), an AFP can be a marker of a disease process/disease involvement, an indicator of something awry, an AFP is looked at and made note of, for other reasons and in other disease states, other than just big ole scary liver cancer!

People can have an temporarily increased AFP (a small blip, or, sometimes marked) simply in response to having hepatitis, and never have cancer! I used to think that, that an over-limit AFP meant, .... eww... elevated, then e-gads, i could have cancer!! It is NOT accurate enough to base anything on an AFP alone - just remember, some people have liver tumours/lesions/cancer and their AFP was normal or near normal, the next person had NO cancerous liver tissues, ever, and yet their AFP blipped upward while they had chronic hep. AFP's are a good a useful tool, when combined with other tests, and repeated over time. It's always a good basic test to have (in my book). 

Lamassu too has twigged onto the careful usefulness in having AFP's done, but still, an elevated result may not necessairyly spell scary-dom. Jes sayin.winksmile C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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thanks tig, that does make sense to me



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

Tig


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Hello 5,

I thought I’d provide the information you asked about in Ziggy’s thread, here. The A2M is primarily produced in the liver and is an active part in immune function, protease inhibition, and clotting, among others. They even diagnose Alzheimer’s or tendency to it in some because a continued deficiency of it may lead to formation of the plaques responsible for it. It can tell of kidney dysfunction, pancreatitis, liver disease, clotting disorders, and a host of other stuff. It’s quite busy! Just know, it’s one of dozens of serum components that all combine to tell the bigger story. We have an amazing system!

Alpha-2 Macroglobulin is a serine proteases inhibitor, which inhibits coagulation by inactivating thrombin and Kallikrein, it inhibits fibrinolysis by inactivating plasmin and involved in transport. Alpha-2-Macroglobulin is a large plasma protein, which is produced by the liver, it’s composed of 4 identical subunits bound together by -S-S- bonds. A2M is able to inactivate many kinds of proteinases (including serine-, cysteine-, aspartic- and metalloproteinases). A2M has a 35 amino acid "bait" region in its structure. Proteinases bind and cleave the “bait” region become bound to A2M. Macrophage receptors recognize the proteinase-A2M complex and clear it from the system. A2M binds to and removes MMP-2 and MMP-9 (active forms of the gelatinase) from the circulation using scavenger receptors on the phagocytes. The levels of Alpha-2-macroglobulin are increased in nephrotic syndrome which is a condition where the kidneys start to leak out some of the smaller blood proteins. Due to its large size, A2-macroglobulin is retained in the bloodstream. Increased production of all proteins causes A2-macroglobulin concentration to increase. Chronic renal failure might lead to amyloid by alpha-2-macroglobulin. A2M is raised in cirrhosis, pregnancy and diabetes.



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hey C, casino's are all flashy and lookin fun that's for sure, but the smelly smoke and losing money$$$$$$$$$$$$ are not as fun.[ we have table fans so i love the bosses for bringing them]

and def they have changed thru the times to attract more ppl.

i still have fun where i work, but don't go to any besides work



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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hi C, in a way i was expecting to be tested for more VL and liver panel; hubs was but he did 12 weeks not 8 like me.

so maybe they figure since i only did 8 it was ok to wait.... either way is ok with me... and as far as medical teams go they have some lose ends over there. hahahaha blankstare; but they got me the harvoni so the rest is just waiting to know the final score and trusting it remains und and in healing mode now.

 



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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5, 

HA! Asking Tig about his coffee consumption .... well .... (I have found most addicts, whatever it may be, will tell you the conversation matter is "not on the table" for discussion! heehee), but, I have it on good record, tween you and me, that you may be on to sumpin! Some people near-mainline the stuff, I have heard of others who have even wasted a perfectly good cuppa via enemas and such, of all things! (Let's not go there BTW), but Tig? ... ya I do wonder about his (and Ob's) double, quadruple blotto/blottos. hee hee C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

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Hey 5,

Going back over some of the posts here, I am not sure if you were expecting a EOT VL , at the end of your 8 week treatment, or not??

Had your doc clarified for you (ahead of time) what and when your blood tests would occur for you and what they would include?? 

He should have, then there are no surprises.

So with your beautiful UND at 4 weeks, and good LFT's, these are the cardinal/important indicators, which will carry you until EOT+12 (SVR12).

BTW - I was never in a Casino until about 10 years ago, I begged my partner to stop so I could look inside - I was shocked, I was expecting to see Frank Sinatra and old fashioned slot machines, like a movie in my mind I guess! I am glad you got a couple extra days off for yourself to celebrate/rest with.

You done it girl! Whew. Nothing now but better health, recovery, regeneration, and a world of knowledge, learning, sharing and all your new friends here! wink C.

 

 



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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hi tig,

have you checked the obvious suspects for insomnia.

caffeine too late in the day. indigestion. activity or intense tv shows too close to bed. thinking about all the stuff you could be doing or rather be doing instead of sleeping? that last one is a big one for me so i have to remind myself i'm a human being not a human doing.

but the b12 really does help with everything i agree with that.  but i have to take it when i wake up so it doesn't add to insomnia.

if i don't have to work i can usually sleep well enough, unless i have an appointment, that's all i can think aboutcry.

but on work nites the 1mg. valium is a life saver, and i'm no more or less tired than i normally am. i still drink lots of water and have coffee early , and no later than 11pm for a 6am bedtime.

not sleeping is harder on the bod than that little bit of groggy feeling i might have.

so, how about the pot for the preglaucoma? i'm not a fan of the pot but now days they have so many products that don't give you the fuzzy feeling..... but maybe that would help sleep too.

i'm praying sleep will start happening to you easily from now on. 5



-- Edited by 5-1-18 on Wednesday 27th of June 2018 05:33:28 AM

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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

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Thanks 5! I’ve been doing some reading since we first spoke and I’m finding a lot of interesting information on the different benefits B12 provides. It looks to actually increase as we age. I’ve got pre glaucoma and my Dad has been plagued with AMD (Macular Degeneration), so I’ve got to be very forward thinking with my eye health in particular. Even though my B levels are adequate, studies show proper supplementation and diet will really make a positive difference. If I could find something to help the insomnia, I’d be golden!



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67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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tig here is my b12 info

Vitafusion is the one i cut into thirds and quarters for my treatment time. . 2 gummies=1000 mcg/500 apiece

then at wallyworld i found these Spring Valley adult gummy b12 . 2 gummies = 500mcg/250 apiece.

i think it's more tolerable to take low daily doses rather than a shot. it seems to work for my system. and they are fun to eat.

i haven't tried the spring valley one since i have lots of the vitafusion already cut up. 

it really is better on the body to start low and work up, better than how i started high and worked down.

and here is the 100mcg : Solgar - Vitamin B12, 100 mcg, 100 Tablet

 



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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thank you lamassu biggrin



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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Hi 5,

Congrats on EOT!



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hi tig, i def woke up smiling todaybiggrin , inside and out.

my b12 journey was really something..... the doc ordered mega dose at first since my labs showed very low. i tried the 3000 and my whole body twitched and i couldn't sleep.

so. i tried the 500, i was still too wired.

i ended up taking a 500 gummy  and cutting it in half for awhile. on the harvoni i took half of a half

now i will figure out what i need.. still going with 125mcg for now.

we also have 100mcg pills so might just go with that now that calcium isnt a worry.

i do like the gummies tho, and they work good for me

i have always been a low dose person [ 1/4 or 1/2 of a 200mg advil; a bit of dust on finger for the claritin.... everything except harvoni and antibiotics i will cut down into miniscule doses].

 

so i recommmend the gummies @ 500. i have one that come as a dose=1000 [2 gummies], and another that is 2=500, so 250 per gummie

you have to read the labels, but amazon has them too. i will post the names later as i am reclining watching tv and playing on the laptop drinking my morning [4pm ] coffee.



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

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What kind of B12 do you take? I’ve been seeing ads for a sublingual type that is supposed to superior to the pill route. My PCP gives everyone shots that want them, but my serum B12 is good, so I haven’t gone that route. Daily multi vit is all I do and so far it works. I’m searching for that little extra boost, legal type, lol!

So glad things are better for you. I knew they would be and believe over time, you’re going to really notice improvements. Defeating the virus is such an important leap in health benefits. Far more than the obvious. There are so many systems affected by the virus when it’s allowed to fester. People that come here with no apparent complaints pre-treatment, realize afterwards that they really were experiencing issues. 

Keep hydrating, stay active and always keep that smile going, inside and out! smile



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67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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ok, so honestly, i didn't miss taking the magic bean tonite....... i think i said a heart felt good--bye on the last pill and yep; it was good being at work knowing "no pill tonite ", and being home and realizing that ritual is over.

i have 3 days off to chill out and drink water , take walks letting all the side effects go.... working will be so much easier now . they let me sit down when ever i could so that helped tonite too.

and also honestly, i don't think i could work much if i had to do the 12 week. so i am thankful it all worked out like it did.



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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well the good news is i don't test for 3 more months.... i don't mind that at all i mean , who really likes to get blood drawn? i rather wait anyway since already knowing 4 weeks UND.

 

so, i'm gonna dance, dance ,dance  ...and check in here with other posts.

going to work tonite, thankful eot was at 8 weeks for me

for me the feeling weak and tired and dizzy were the main things i look forward to getting rid of now. 

the stomach can be treated without worries now... and hopefully in time that will also be resolved...maybe the virus took the gallstones with it biggrin

see you all around the forum. 5



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

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HOORAY! Welcome to EOT

 

Congrats 5, I’ve been wearing my platform shoes all night long, just waiting for the first dance, but darn it, looks like I’m running late, lol! Oh well, this party is going last forever, so put me on the dance card!

8C9F760A-1E03-4666-8369-AF013538A8C6.jpeg



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67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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canuck, seethelight,observer

, yes that little pill was like my very special charge, to look after and meeti it's needs and take it at the right time.

and yes, now it has left the gift in me and i can always remember the relationship with love and joy....knowing that gilead created the magic bean just for this gift to me.

plus i pee them out anyway with floods of water... just a thot. hahahaha biggrin

i let go the oars and know that my immune system motor is more than capable of taking it from here

what a fun time for all to see another eot happening on the forum

so excited for my last pill in a little over an hour

today i rested most of the day so i can go forth rested on monday night to work with eot d.o.n.e.



-- Edited by 5-1-18 on Monday 25th of June 2018 04:27:10 AM

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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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Congratulations on reaching your eot.    

Its almost surreal to think about living without that stupid virus, eh?  

I can attest that its pretty awesome and wonderful



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Oh So True Canuck,

I cannot imagine no more magic beans either. They have been the focus of my life for the last 8 weeks. I know it is going to be so weird in four weeks time when I am in 5's position (and yours in the past) 7.30 am will not be the same, I am sure. They have become the most important thing in life. I can't envision no more......Funny, my hep never was before.



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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5, 

You said ... "gee, i'm almost gonna miss the little magic beans after depending on their help for 2 months... as my body says "thanks for assist good buddies"... 


Funny that, how we feel that way, once the bottle no longer rattles, our "buddies" gone, done their work and we are on our strong and healthy own again - feels a little naked or empty without that bravery back-up crew around, we got used to the damn pills being there, daily representing such strength, hope, promise, insurance.

You don't need 'em any more - you've now unwrapped that lovely gift that was given to you. Congrats on your EOT! winkbiggrin C.

 



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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yours may be a little brighter colour but I couldn't get as good of pic as you got.



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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Yep it sure does 5.....spun me out when I saw your pic...They must make em all out of the same mold...rofl

 



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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SeeTheLight wrote:

wow 5.....mine looks like its twin confuse

must be diff number on other side. 7916


 does your epclusa look like the harvoni ?

7985 is the number  on the other side. 



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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Tig wrote:

Okay 5,

Ive got my dancing shoes polished and the Disco Ball is ready to light up the room!! Your journey is almost complete and the robust (?) Lady is about to sing, WOOHOO! This is end of the line for you, prepare to disembark the Harvoni Train...

EOT-Ville Station is your next stop.

5293EDAF-9284-4CB3-B632-647FC6F3F041.gif


 indeed! i love that little picture. yes, i am preparing to disembark the harvoni train; last stop in 11 hours . i love that little pill , still i am prepared to move forward, and onward without my little magic bean...

i have the magic in me now



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0

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Okay 5,

I’ve got my dancing shoes polished and the Disco Ball is ready to light up the room!! Your journey is almost complete and the robust (?) Lady is about to sing, WOOHOO! This is end of the line for you, prepare to disembark the Harvoni Train...

EOT-Ville Station is your next stop.

5293EDAF-9284-4CB3-B632-647FC6F3F041.gif



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wow 5.....mine looks like its twin confuse

must be diff number on other side. 7916



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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gee, i'm almost gonna miss the little magic beans after depending on their help for 2 months...

as my body says "thanks for assist good buddies". 

what a trip this really is



-- Edited by 5-1-18 on Sunday 24th of June 2018 07:05:06 AM

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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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heehee. Still looks like a mighty big and powerful pill to swallow! Saving the best to last eh?!

Give that bottle one last shake, it will be the last time you have to do the maraca, then, it will be that blissful cured silence ... golden!

Only one more sleep! 

Or ... hm, is that one and 3/4's sleep - oh, nevermind, I give up, all I know is that it is wonderfully close to your stellar finish!!! biggrin C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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i found a smaller pill pic. biggrinbiggrinbiggrin



-- Edited by 5-1-18 on Sunday 24th of June 2018 06:12:59 AM

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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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24 hour count down to last pill

 

 

Image result for harvoni pill images



-- Edited by 5-1-18 on Sunday 24th of June 2018 06:12:12 AM

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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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I too very much enjoy these glimpses into each others lives and what we share about oursleves and our places - growth hormones I figure.

yes C, it's like getting together for coffee and cakes [ok, a quart of  water for now ] , and visiting. feels so happy.



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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stl, we have dry high desert weather, not too much humidity..... i dislike humid weather

i had my walk when it cooled down, did some sewing till then........ nice and slow like.

i hope you had a nice walk with puppa even tho chilly-ish



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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hi canuck, 

If I could just remember,

a name when I demand,

list a title, author, date,

 

I'd feel some command. 

 

this is so good, and so true. , thankyou

 



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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Hey I found that poem for you 5,  AND, of course ... that was my bad ... about not being able to maraca with Harvoni (all of Gilead's stuff I think does come in  playful bottles), it's Mav's who have to sing along to a blistering mean snap, crackle, and pop rhythm when they celebrate.

What time is it? - oh my, now don't get me going, between North America and Australia, I would just be lost, I can't get past figuring out night shift, let alone ask me to move between one Canadian Provincial time zone and the next! No counting, or i will have to call in back-up, my human timepiece, calendar, calculator, and figurer-outer. 

I too very much enjoy these glimpses into each others lives and what we share about oursleves and our places - growth hormones I figure.

Neat stuff when we all get to see things like ... well just about anything ... from babes, to emu's, to hurricanes, real lizards, ospreys, oceans afar, ships, planes, trains, cars and motorcycles! My we have travelled a far peice eh?! 

This IS a neat place to come to! smile

 

Aging

Never was no good at math

nor speelin much either.

Uncoordinated,

sports, dance not learned neither.

 

So you'll hardly notice,

my counting's worse.

Disguised are my deficits

when I swing an empty purse.

 

My memory is going,

teeth following soon I fear

I smile at ya on the street

figure later who yer were.

 

Armed with reader glasses

sporting two pairs on head,

while hunting for my lists,

lost treasures found instead.

 

Can't read the shampoo bottle

no lather in conditioner,

my hair is dirty but oh so soft

whatever's left up there.

 

How did I ever get so much done,

like in the past,

my lists are not working,

things are going way too fast.

 

Like a sucking vortex

too soon all things do pass,

Yesterday a babe

now I ignore my ass.

 

Rush about the room

missing paper in hissy-fit,

in humbled rage I find it

tucked under my armpit.

 

What a deal, what a steal

off to the Friday sale!

Pay full price, it's Saturday,

bargain days derailed.

 

Periodically memorize

my age, I tend to forget,

just in case someone asks,

I dread these deficits.

 

Warm up stiff legs,

three trips from house to car,

before the keys are found,

right where they are!

 

My hearing is all wonky,

we fight about mumbling ways.

Tastebuds worn and wanting,

the kitchen's stale to play.

 

Hide my collection of burnt rice pots,

steam veggies dry,

eat crisp pork chops, a lot,

he doesn't ask me why.

 

Milk in the cupboard,

cereal in the fridge,

who the hell did that I say,

damned synaptic bridge!

 

If I could just remember,

a name when I demand,

list a title, author, date,

I'd feel some command. 

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



Senior Member

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Have a good rest and a nice walk later. I've not been enjoying the cold of late, but its a nice day in the making sun is coming out for a bit, so will take the puppa for a walk....Currently 6.8 C (looks like 44.8 F) expecting 13. or 55.4 F. I don't like the cold. Our hot weather is a nice dry heat which I enjoy. I not likey that muggy humid heat at all - thankfully we don't get much of that type of heat in my part of the country. Lovely chatting biggrin



__________________

66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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4:50 saturday afternoon here :)

it was fun to chat with you today

i'm going to get off the bed now and have some dinner, then see if i can sew a few things. then take a short walk when it cools down. in the 90's over here today

have a wonderful day stl.

5



__________________

Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.J*13weeks=UND * 6 m =UND: CLUB ZERO.1yr.=0



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I take it at 7.30 AM. Sometimes I  sit with pill in hand waiting for the ding, other times phone dings and I do as soon as I can grab it. (never more than 5 mins) It in 9.17AM Sunday here



__________________

66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND

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