Thanks for that information Mallani. That was very helpful!
mallani said
Jun 22, 2013
Low platelets are common in cirrhotics and especially during Rx. At 48 weeks my platelets were down to 38,000 ( normal range 150,000- 400,000). Before Rx, my platelets were 185,000. Low platelets are not really a problem, unless you like playing with sharp knives. If your doctor is worried, you can get a transfusion of platelets or use a drug like Promacta.
White blood cells will drop due to bone marrow suppression from Riba and Peg. The neutrophil count is the only important one. I dropped to 0.7 and some have dropped to 0.5 Again, this is not a big deal, but drugs like Neupogen will cause rapid rise in Neutrophils.
Low Hb and RBC'c are often treated by lowering the dose of Riba. Blood transfusion may be needed for severe cases, and Procrit is often prescribed in the USA when the HB drops below 10. I dropped to 7.1 which made life difficult, but I was almost back to normal(16.5) 8 weeks after Rx finished.
How you're managed depends on your doctor. Rx has been stopped in many cases.
-- Edited by mallani on Sunday 23rd of June 2013 03:29:26 PM
Tig said
Jun 18, 2013
I understood that there is a medication available to boost WC production. My doc mentioned to me that should my WC level plummet and throw me in an anemic tail spin, he would admit me long enough to get a blood transfusion. I had trouble with that the first time, 16 years ago. I was stopped back in that day.
Biggyb said
Jun 18, 2013
Hi JLynch30, all i know is live with it.
My GI told me even if i get SVR, my platelets will probably always be low.
JLynch30 said
Jun 17, 2013
Hello,
Does anyone have information about how to manage low platelets and if there are any new studies going on for no responders?
Thanks.
-- Edited by JLynch30 on Monday 17th of June 2013 10:48:10 PM
Thanks for that information Mallani. That was very helpful!
Low platelets are common in cirrhotics and especially during Rx. At 48 weeks my platelets were down to 38,000 ( normal range 150,000- 400,000). Before Rx, my platelets were 185,000. Low platelets are not really a problem, unless you like playing with sharp knives. If your doctor is worried, you can get a transfusion of platelets or use a drug like Promacta.
White blood cells will drop due to bone marrow suppression from Riba and Peg. The neutrophil count is the only important one. I dropped to 0.7 and some have dropped to 0.5 Again, this is not a big deal, but drugs like Neupogen will cause rapid rise in Neutrophils.
Low Hb and RBC'c are often treated by lowering the dose of Riba. Blood transfusion may be needed for severe cases, and Procrit is often prescribed in the USA when the HB drops below 10. I dropped to 7.1 which made life difficult, but I was almost back to normal(16.5) 8 weeks after Rx finished.
How you're managed depends on your doctor. Rx has been stopped in many cases.
-- Edited by mallani on Sunday 23rd of June 2013 03:29:26 PM
I understood that there is a medication available to boost WC production. My doc mentioned to me that should my WC level plummet and throw me in an anemic tail spin, he would admit me long enough to get a blood transfusion. I had trouble with that the first time, 16 years ago. I was stopped back in that day.
Hi JLynch30, all i know is live with it.
My GI told me even if i get SVR, my platelets will probably always be low.
Hello,
Does anyone have information about how to manage low platelets and if there are any new studies going on for no responders?
Thanks.
-- Edited by JLynch30 on Monday 17th of June 2013 10:48:10 PM