Yes I see now after looking at the diagram. Und @ wk 4 references the period after starting Victrelis. Seems I have gone one better than that with Und after the lead in. Anxoously awaiting the next VL test
Overall I am not feeling too bad. Live in constant fear of missing pills but I have smartphone alarms going off all day
mallani said
Jul 29, 2014
Hey Paul,
The RVR definition for Victrelis is Undet. after 4 weeks on Victrelis, and eRVR is 4 weeks later.
With your Undet. after the leadin, I'm not sure how this works out, but I'd press for a 9 week VL just to make sure.
With a Hb of 158, you should feel OK. Mine had dropped to 81 by week 8. Carry on buddy, and don't miss any pills!
Paul B said
Jul 29, 2014
Hey Mal,
last Hb was 158, so went up a couple of points. Week 8 becomes week 9 for me, so I guess next VL load check is 3 weeks from tomorrow. Neutophils was 1.1.
-- Edited by Paul B on Tuesday 29th of July 2014 10:44:22 AM
mallani said
Jul 29, 2014
Hi Paul,
How's your Hb holding up? The Riba rash is a bit of a pain. Don't scratch and some topical low-dose steroid ointment are useful
When's your next VL? Cheers.
Paul B said
Jul 29, 2014
I am in week 8 on triple, but with Victrelis. I am pretty tired, rash on face feel a bit crap, and my body feels hot to touch. Overall though, the side effects have been much less severe than anticipated. Many days I have barely felt anything at all. I was undetectable at week 4. Hope this time it is gone for good.
Scruffy said
Jul 27, 2014
Theres some of us here that were and are still on that treatment. I'm a 48 week-er. I was still undetectable at 7 weeks post treatment. We are here for you guys. Remember that it helps to know there are peeps that have been down the road your on to seek advise from.
Midnight said
Jul 27, 2014
Hi
I'm on week 27 of the triple.
I found that by the time the Telap had built up enough in my system to begin to really upset me it was almost week 12.
What I found was the Telap made me very tired but not enough so I couldn't get around, a random itch appeared which was always worse before bedtime and if I didn't eat enough fat with it I had the most terrible ring sting!
For a few days after the Telap was over I had a terrible bout of itchyness which then went. A week or so later I felt much better and discovered a new found energy.
I wouldn't be worried about whether its working or not as although I had minimum sides I was UND at 4 weeks...
Best wishes
Isiscat2011 said
Jul 27, 2014
Hi buny:
When a bunch of us here were on the Incivek tx we used to speculate about what the severity of our initial side effects meant. Some people had a theory that the worse the side effects the better your odds for SVR. That is probably malarkey. The only real indicator of how the virus is holding up under the attack of the drugs is the viral load test. The 4 week blood test is quite significant. It will tell you whether you have achieved RVR (rapid viral response). Those who RVR have significantly increased odds of SVR.
My first 48 hours was a complete friggin nightmare! I can laugh about it now but it was quite scary. I took the first shot on Friday night. By Sat I felt like I had a bad case of the flu. By Sunday I felt completely disoriented and had a rash over 90% of my body. My doc was on call so I called him. He was saying we may have to discontinue tx because this rash business can be serious. Doc said come in first thing in the morning on Monday. I waited until either late Tuesday or maybe Wednesday to see him because the rash was improving and I wanted it to look better when I saw him (not very smart I know). I also felt too sick to go to the doctor. lol
Everyone's experience is different and you can't know what will happen from one day to the next. I've never met anyone who said they had no side effects on this tx, but for some it was minimal, and they are even able to work through most of it. I hope that is what happens for you and that you achieve SVR. Try to relax and take it one day at a time. We are here for you. :)
Btw, I mistakenly had my first vl check in the 3rd week instead of the 4th and I had gone from 11 million to UNDETECTABLE. The drugs you are on can kick some virus butt.
dragonfly said
Jul 27, 2014
Good luck, I know this is a horrible regime - take it easy.
mallani said
Jul 27, 2014
Hi buniaminmd,
Welcome. I'd enjoy being side-effect free while you can. I presume you are Geno 1 and will be doing at least 24 weeks.
With the Incivo (Incivek) triple, the 4 week Viral Load is a great indicator of your chances of SVR, so we look forward to seeing your results.
Incivo is very potent and I hope you have minimal problems. Don't forget the 20 gm of fat! Cheers.
Scruffy said
Jul 27, 2014
Hiya bunyaminmd
I was on that tx, peg/riba/incivek. I had about the same reaction to the shots. They got easyer for me with time. Make sure you eat the 20gm of fat with the incivek. Don't be worried about having no side effects. I'll be honest I didn't have any untill about the third week. the drugs have to build up in your system.
Good luck on your treatment.
Huey said
Jul 27, 2014
I Don't won't you to go without some kind of answer so I am going to give you a quick reply hoping you feel some re leaf from the anxiety.
Nothing is normal about this virus. I know nothing about your tx so i can't say, but everybody else that is taking these new meds knows they do work. Expect a roller-coaster ride in the first two weeks. and if all you get is a pony ride, feel lucky and take it.
We are all in this together Keep your stick on the ice. ;Red Green Show;
bunyaminmd said
Jul 27, 2014
I am at third day (about 48 hours) on thriple tx with incivo.
First night, (8 hours after injection) : I chilled for 2 hours and it has past. At second day i had little muscle and joint pains.
And now at third day. I have about NOTHING. is it normal? I am confused about tx is working or not???
Yes I see now after looking at the diagram. Und @ wk 4 references the period after starting Victrelis. Seems I have gone one better than that with Und after the lead in. Anxoously awaiting the next VL test
Overall I am not feeling too bad. Live in constant fear of missing pills but I have smartphone alarms going off all day
Hey Paul,
The RVR definition for Victrelis is Undet. after 4 weeks on Victrelis, and eRVR is 4 weeks later.
With your Undet. after the leadin, I'm not sure how this works out, but I'd press for a 9 week VL just to make sure.
With a Hb of 158, you should feel OK. Mine had dropped to 81 by week 8. Carry on buddy, and don't miss any pills!
Hey Mal,
last Hb was 158, so went up a couple of points. Week 8 becomes week 9 for me, so I guess next VL load check is 3 weeks from tomorrow. Neutophils was 1.1.
-- Edited by Paul B on Tuesday 29th of July 2014 10:44:22 AM
Hi Paul,
How's your Hb holding up? The Riba rash is a bit of a pain. Don't scratch and some topical low-dose steroid ointment are useful
When's your next VL? Cheers.
I am in week 8 on triple, but with Victrelis. I am pretty tired, rash on face feel a bit crap, and my body feels hot to touch. Overall though, the side effects have been much less severe than anticipated. Many days I have barely felt anything at all. I was undetectable at week 4. Hope this time it is gone for good.
Theres some of us here that were and are still on that treatment. I'm a 48 week-er. I was still undetectable at 7 weeks post treatment. We are here for you guys. Remember that it helps to know there are peeps that have been down the road your on to seek advise from.
Hi
I'm on week 27 of the triple.
I found that by the time the Telap had built up enough in my system to begin to really upset me it was almost week 12.
What I found was the Telap made me very tired but not enough so I couldn't get around, a random itch appeared which was always worse before bedtime and if I didn't eat enough fat with it I had the most terrible ring sting!
For a few days after the Telap was over I had a terrible bout of itchyness which then went. A week or so later I felt much better and discovered a new found energy.
I wouldn't be worried about whether its working or not as although I had minimum sides I was UND at 4 weeks...
Best wishes
Hi buny:
When a bunch of us here were on the Incivek tx we used to speculate about what the severity of our initial side effects meant. Some people had a theory that the worse the side effects the better your odds for SVR. That is probably malarkey. The only real indicator of how the virus is holding up under the attack of the drugs is the viral load test. The 4 week blood test is quite significant. It will tell you whether you have achieved RVR (rapid viral response). Those who RVR have significantly increased odds of SVR.
My first 48 hours was a complete friggin nightmare! I can laugh about it now but it was quite scary. I took the first shot on Friday night. By Sat I felt like I had a bad case of the flu. By Sunday I felt completely disoriented and had a rash over 90% of my body. My doc was on call so I called him. He was saying we may have to discontinue tx because this rash business can be serious. Doc said come in first thing in the morning on Monday. I waited until either late Tuesday or maybe Wednesday to see him because the rash was improving and I wanted it to look better when I saw him (not very smart I know). I also felt too sick to go to the doctor. lol
Everyone's experience is different and you can't know what will happen from one day to the next. I've never met anyone who said they had no side effects on this tx, but for some it was minimal, and they are even able to work through most of it. I hope that is what happens for you and that you achieve SVR. Try to relax and take it one day at a time. We are here for you. :)
Btw, I mistakenly had my first vl check in the 3rd week instead of the 4th and I had gone from 11 million to UNDETECTABLE. The drugs you are on can kick some virus butt.
Good luck, I know this is a horrible regime - take it easy.
Hi buniaminmd,
Welcome. I'd enjoy being side-effect free while you can. I presume you are Geno 1 and will be doing at least 24 weeks.
With the Incivo (Incivek) triple, the 4 week Viral Load is a great indicator of your chances of SVR, so we look forward to seeing your results.
Incivo is very potent and I hope you have minimal problems. Don't forget the 20 gm of fat! Cheers.
Hiya bunyaminmd
I was on that tx, peg/riba/incivek. I had about the same reaction to the shots. They got easyer for me with time. Make sure you eat the 20gm of fat with the incivek. Don't be worried about having no side effects. I'll be honest I didn't have any untill about the third week. the drugs have to build up in your system.
Good luck on your treatment.
Nothing is normal about this virus. I know nothing about your tx so i can't say, but everybody else that is taking these new meds knows they do work. Expect a roller-coaster ride in the first two weeks. and if all you get is a pony ride, feel lucky and take it.
We are all in this together Keep your stick on the ice. ;Red Green Show;
I am at third day (about 48 hours) on thriple tx with incivo.
First night, (8 hours after injection) : I chilled for 2 hours and it has past. At second day i had little muscle and joint pains.
And now at third day. I have about NOTHING. is it normal? I am confused about tx is working or not???