lol positive for antibodies for life sounds alarming ...from what you say the virus and antibodys are 2 totaly different things....
i will research as to why a person may for life have hcv antibodys ... thanks for the info malcolm.... everytime i hear you or other people comment i learn sumthing....
Hi Josh,
I've been infected with HIV/HCV for 20+ years and have yet to really learn very much about HCV. But I know a little about how the immune system works concerning HIV. Although I'm fairly sure I'm at least close to accurate in my kindergarten description, I can certainly be mistaken about any part of it. So please keep this in mind.
When the immune system identifies invading viruses, bacteria etc. it triggers a response through the lymph systems macrophage which then triggers 'Helper T Cells' . These T cells alarm the systems B cells. These B cells are what produce "antibodies" specific to fighting off the invading infection. Once the invading virus has been eradicated, suppressor T cells reduce the production of fighter antibody's but some remain in case of a future attack by the same invading virus.
It's kind of how they produce flu vaccines engineered to fight a particular strain of flu . The way I understand it the vaccine is actually a flu virus, but an inactive one incapable of replication. But this inactive flu virus does still trigger the immune system to go through the process as I described. That way, if your body is invaded by this strain of flu, the immune system has already produced antibodies ahead of time to fight it off quickly = no replication of the infection.
I assume that with HCV, the Rx's we take attack the virus itself, not the antibodies. After the virus has been cleared (SVR), suppressor T cells reduce the production of antibody's just like with other invading viruses foriegn biological threats etc. including HIV. And some HCV antibodies remain in case of future encounters with your particular geno / strain of the virus.
Again, I'm likely not entirely accurate with my description. This is just how I understand it.
Josh Haynie wrote:
this forum and its members new and veteran alike are truly great ...
I agree!!!
-- Edited by wmlj1960 on Friday 1st of August 2014 07:13:14 AM
yes and the reason HCV does not act like a flavinvirus has to do with this signaling of the T cells, Flavinvirus's get around this. No T cells are called.
wmlj1960 said
Aug 1, 2014
Josh Haynie wrote:
lol positive for antibodies for life sounds alarming ...from what you say the virus and antibodys are 2 totaly different things....
i will research as to why a person may for life have hcv antibodys ... thanks for the info malcolm.... everytime i hear you or other people comment i learn sumthing....
Hi Josh,
I've been infected with HIV/HCV for 20+ years and have yet to really learn very much about HCV. But I know a little about how the immune system works concerning HIV. Although I'm fairly sure I'm at least close to accurate in my kindergarten description, I can certainly be mistaken about any part of it. So please keep this in mind.
When the immune system identifies invading viruses, bacteria etc. it triggers a response through the lymph systems macrophage which then triggers 'Helper T Cells' . These T cells alarm the systems B cells. These B cells are what produce "antibodies" specific to fighting off the invading infection. Once the invading virus has been eradicated, suppressor T cells reduce the production of fighter antibody's but some remain in case of a future attack by the same invading virus.
It's kind of how they produce flu vaccines engineered to fight a particular strain of flu . The way I understand it the vaccine is actually a flu virus, but an inactive one incapable of replication. But this inactive flu virus does still trigger the immune system to go through the process as I described. That way, if your body is invaded by this strain of flu, the immune system has already produced antibodies ahead of time to fight it off quickly = no replication of the infection.
I assume that with HCV, the Rx's we take attack the virus itself, not the antibodies. After the virus has been cleared (SVR), suppressor T cells reduce the production of antibody's just like with other invading viruses foriegn biological threats etc. including HIV. And some HCV antibodies remain in case of future encounters with your particular geno / strain of the virus.
Again, I'm likely not entirely accurate with my description. This is just how I understand it.
Josh Haynie wrote:
this forum and its members new and veteran alike are truly great ...
I agree!!!
-- Edited by wmlj1960 on Friday 1st of August 2014 07:13:14 AM
Fireman Rob said
Jul 31, 2014
Hi Josh,
Yes, there are thousands of people that have been exposed to the antibodies but it never develops into an active virus. For some reason, more women and young children keep the virus at bay and never need meds to clear a viral load. Just food for thought...
Josh Haynie said
Jul 31, 2014
lol positive for antibodies for life sounds alarming ...from what you say the virus and antibodys are 2 totaly different things....
i will research as to why a person may for life have hcv antibodys ... thanks for the info malcolm.... everytime i hear you or other people comment i learn sumthing.... this forum and its members new and veteran alike are truly great ...
mallani said
Jul 30, 2014
Hi Sheila,
Sounds as if you had your antibody testing done with the Ortho Vitros anti-HCV 3.0 Chemiluminescence Assay. As far as I know, that's the only one with a signal to cut-off ratio of 1.00
The fact that you're positive is hardly surprising. All HCV patients will be positive for antibodies, usually for life. It does not mean relapse.
If you're worried, get your viral load done, with a PCR test. Cheers.
Matt Chris said
Jul 30, 2014
Hello Sheila
Do you know what exact test was run?
Sometimes the test for the HCV antibodies is run, which is not a sure indicating that you have a viral load
matt
hrsetrdr said
Jul 30, 2014
I "transplanted" this Chatbox message posted by Sheila, who is a new member. I did this because we encourage members to start a message thread in one of the Forum's sub-sections, thus giving other members an opportunity to convey information and comments.
After my hep c treatments ended, I showed that it was cleared through lab work. 7 years later, i had lab work done again and it shows positive and the level should be less than 1.00 and mine is 32.3. Am I infected again? I haven't done any risky behavior in all those years.
BTW, Welcome to the Forums Sheila, there are members here who might be able to give you some direction with this matter.
-- Edited by hrsetrdr on Wednesday 30th of July 2014 07:45:58 PM
yes and the reason HCV does not act like a flavinvirus has to do with this signaling of the T cells, Flavinvirus's get around this. No T cells are called.
Hi Josh,
I've been infected with HIV/HCV for 20+ years and have yet to really learn very much about HCV. But I know a little about how the immune system works concerning HIV. Although I'm fairly sure I'm at least close to accurate in my kindergarten description, I can certainly be mistaken about any part of it. So please keep this in mind.
When the immune system identifies invading viruses, bacteria etc. it triggers a response through the lymph systems macrophage which then triggers 'Helper T Cells' . These T cells alarm the systems B cells. These B cells are what produce "antibodies" specific to fighting off the invading infection. Once the invading virus has been eradicated, suppressor T cells reduce the production of fighter antibody's but some remain in case of a future attack by the same invading virus.
It's kind of how they produce flu vaccines engineered to fight a particular strain of flu . The way I understand it the vaccine is actually a flu virus, but an inactive one incapable of replication. But this inactive flu virus does still trigger the immune system to go through the process as I described. That way, if your body is invaded by this strain of flu, the immune system has already produced antibodies ahead of time to fight it off quickly = no replication of the infection.
I assume that with HCV, the Rx's we take attack the virus itself, not the antibodies. After the virus has been cleared (SVR), suppressor T cells reduce the production of antibody's just like with other invading viruses foriegn biological threats etc. including HIV. And some HCV antibodies remain in case of future encounters with your particular geno / strain of the virus.
Again, I'm likely not entirely accurate with my description. This is just how I understand it.
Josh Haynie wrote:
I agree!!!
-- Edited by wmlj1960 on Friday 1st of August 2014 07:13:14 AM
Hi Josh,
Yes, there are thousands of people that have been exposed to the antibodies but it never develops into an active virus. For some reason, more women and young children keep the virus at bay and never need meds to clear a viral load. Just food for thought...
lol positive for antibodies for life sounds alarming ...from what you say the virus and antibodys are 2 totaly different things....
i will research as to why a person may for life have hcv antibodys ... thanks for the info malcolm.... everytime i hear you or other people comment i learn sumthing.... this forum and its members new and veteran alike are truly great ...
Hi Sheila,
Sounds as if you had your antibody testing done with the Ortho Vitros anti-HCV 3.0 Chemiluminescence Assay. As far as I know, that's the only one with a signal to cut-off ratio of 1.00
The fact that you're positive is hardly surprising. All HCV patients will be positive for antibodies, usually for life. It does not mean relapse.
If you're worried, get your viral load done, with a PCR test. Cheers.
Hello Sheila
Do you know what exact test was run?
Sometimes the test for the HCV antibodies is run, which is not a sure indicating that you have a viral load
matt
I "transplanted" this Chatbox message posted by Sheila, who is a new member. I did this because we encourage members to start a message thread in one of the Forum's sub-sections, thus giving other members an opportunity to convey information and comments.
BTW, Welcome to the Forums Sheila, there are members here who might be able to give you some direction with this matter.
-- Edited by hrsetrdr on Wednesday 30th of July 2014 07:45:58 PM