I hate just the way it sounds, Failed Sovaldi, Your days is comming,
we are all in this together Keep your stick on the ice. {Red Green Show}
jimbob said
Aug 1, 2014
John--
Our tx histories are are different I know, and maybe the reason my GI feels so confident ; however, i'm obviously concerned. I'm going to take Isiscat's advice and have a 12 week Vl done thru my PCP if possible.
Onto the NEAR future John. The S/L combo is showing super results for non-responders and is ONLY 2-3 MONTHS AWAY!
Jim had excellent advice on walking in the woods, etc. Focus on staying occupied and healthy until the new stuff arrives.
Gracie said
Jul 31, 2014
This sucks big time and I am very sorry you are going through it. I am just starting now to come out of my post treatment failure funk. Didn't feel myself for the longest time, but I was doing the stinky incevik combo which was very hard on my system. I have heard the sovaldi/olysio combo has much better SVR rates for us non responders And can be used after our types of treatments failed after a few months to rid oneself of the residual RIBA crapola. as for maintenance best thing to do is eat clean and take milk thistle (Not sure how much good milk thistle does, but it makes me feel like I'm doing something), No fatty foods and as much exercise as you can fit in to fight fatigue.
I'm feeling much better now almost 5 months post failure and have started to get hopeful again after looking at all that is on the horizon for us. I watched a show on YouTube where a specialist was talking about the new treatments and she said within the next ten years, hep c will be A thing of the past....
JIme said
Jul 31, 2014
Hi John.
I would rest up and drink a lot of water. Try to slowly start to exercise a little at a time. Maybe go for a walk every day if possible and slowly increase the time. A walk in the woods is best if that is an option.
Mentally, when I failed triple tx, I just tried to focus on the fact that my liver got a little break and that I was not done trying. That I would be ready for the next time. I was grateful for the chance I had to try and get rid of it. Not everybody gets a chance. Stay the course John, your day will come.
ps I wish you could have done without the interferon. maybe you explained why already. I apologize if you did or even if you know why.
I would assume it's Gilead trying anything except a partnership with BMS. Anyway......
JLynch30 said
Jul 31, 2014
Thank you - in your case it looks great because you have not used interferon before!
jimbob said
Jul 31, 2014
Oh John, man I thought this was the tx. for you . I feel for you and know you had to be really shocked and disappointed.
I agree with Isis now about checking for. IL28 B or other possible flags that might hinder tx. Personally, I think too many professionals are relying on the 92% cure rate without giving it a second thought. That was the opinion of
my GI anyway who doesnt think it necessary to check my VL until the 6 month mark. I really thought this tx would be potent enough.
Try to stay strong John. I have no experience but the thought of it shakes me. I'm not sure I could be as strong as you are now, but you are taking the right approach by looking forward to the next step.
My hopes are with you and others here waiting for the the new combos.
Cinnamon Girl said
Jul 31, 2014
John, I`m so sorry to hear this, what a huge disappointment it must be for you. Full marks for your determination though in going through another course of interferon based treatment, you should feel very proud of yourself for that.
Take it easy now for a while, nurture yourself physically and emotionally until the next and final round.
Sending all very best wishes, Jill
Bills said
Jul 31, 2014
Sorry to hear the treatment failed Lynch
I had my share I'm happy to you you want to move on . As you know the needle less cures are just about here. I'm on the bus with you Mugsy Hope to see you all at the bus stop
BS
JLynch30 said
Jul 31, 2014
i WAS UNDETECTED FROM WEEK 4 TO 12. 5 weeks after I had labs and it was 8 million. alt/ast sky hi. Any maintenance suggestions while I wait?
Mugsy said
Jul 31, 2014
Disappointing news. I am so sorry. So now you're waiting for the "new treatment bus" with the rest of us. By Springtime, we will light this board up with SVR reports.
Zlikster said
Jul 31, 2014
:( sorry John, what happend exactly while you were on sov/rib/peg tx?
maybe Ledipasvir/Sovaldi combo will be one for ya?
Best
Scruffy said
Jul 31, 2014
Sorry to hear this John.
Next one will be no needles. Talking about herbalists I just got an e-mail from Lloyd Wright he says he misses me.
JLynch30 said
Jul 31, 2014
Thank you all so much for the support. I gave myself an hour of self pity and now I must move on. I have to avoid my own mind telling me to look up every Chinese herbalist in los angeles. Like Malcolm said (my mentor), give it a break. there is a huge hep c meeting september 11th and my doctor will know then - October 10th is the next target date.
I am going to pay out of pocket for fiboscan as my insurance does not cover it yet. It is worth 350 to see what is going on.
Thanks again.
TazKat said
Jul 30, 2014
Still here cheering for u!!! keep the faith. heart is sunk & this is only temporary. know that!!! ur friend Taz
thepoet said
Jul 30, 2014
I know the feeling of a failed treatment. I have had it twice with the interferon and riba and when I had it, there were no new treatments available except the Incevik and my ins would not pay for it because it wasn't suggested for g4. The blessing is that there are new meds coming down the line soon and you will have another opportunity. Keep the faith brother!
Your sister in the fight.
Fireman Rob said
Jul 30, 2014
John,
This is only a minor set back. Keep fighting the good fight. We're all here fighting with you.
-Rob
wmlj1960 said
Jul 30, 2014
Sorry to hear this news John. I'm pretty new here and just started TX, 1st time. I'm scared to death of failing once. I can't imagine 5 fails. But as has already been posted, the 100% SVR - w/ no Inter. is just around the corner.
You are in my prayers.
Dee Dee said
Jul 30, 2014
This is really sad news John.. I know you must be heartbroken. Think of positive thoughts ... There will be a cure around the corner for you and all the relapsers...stay positive.
Caryn said
Jul 30, 2014
John, I am very sorry to hear this news as well. I just hate hearing this. I'm keeping you in my thoughts and prayers!
Gator Man said
Jul 30, 2014
John, I of course concur with all the preceding comments about this setback. I believe we are tantalizingly close to a 100% "cure", but unfortunately as you can attest, not quite there yet. The good news is that the next DAAs are just weeks away, and you will no longer have to suffer with Interferon as Malcolm stated. Like Matt, Greg and others, your time will be here soon!
John
Groupergetter said
Jul 30, 2014
Sorry to hear this John. Believe me I DO know some of what you are going thru. As with you I'm on the wait and wonder? Sometimes it is very difficult to understand. Perhaps there is no understanding it? Just hope we get another opportunity. Be well sir.
hepcinbama said
Jul 30, 2014
hey jl sooooo sorry im on the same treatment an im testing negative for the hep c after 7 weeks but I have to continue then come back in 6 months an see if it came back .is that what happened toyou? an im very sorry for you I have been very sick an know what you are going through what is your geno? mine is 3
Tig said
Jul 30, 2014
Hey John,
Sorry to hear your news as well. There have been a few others with similar results and it's never easy to hear those reports, I don't care who you are. Give yourself sometime to recoup and make plans for the final assault this fall or shortly thereafter. Hang in there buddy....
Tig
mallani said
Jul 30, 2014
Hi John,
I'm really sorry you had to go through that again. It's like a kick in the guts. No more Interferon for you.
You know the next time will work. Whether it takes 6 months or a year doesn't matter. Take it easy buddy.
Isiscat2011 said
Jul 30, 2014
Some people just are not Interferon sensitive. Usually they have a TT or CT IL28b allele. And, Sovaldi needs a good second (or perhaps a third depending on the treatment and its duration).
I don't know why all docs don't check the IL28B before Interferon tx and really think about whether they want to continue putting people on the same tx over and over again. Especially when there are other options so close.
-- Edited by Isiscat2011 on Thursday 31st of July 2014 12:44:03 AM
hrsetrdr said
Jul 30, 2014
JLynch,
I am shocked to hear that the sovaldi/interferon/ribravin regimen failed , so sorry as you must be very disappointed. Hopefully one of the other new tx will do the job for you.
Tim
Isiscat2011 said
Jul 30, 2014
Well, I'm just going to say what we might all be thinking. I'm afraid the real world Sovaldi isn't looking quite as promising as the hype at the moment.
Isiscat2011 said
Jul 30, 2014
I'm so sorry, JLynch. It is especially heartbreaking when someone has repeatedly given it their all. I know you must be feeling so disappointed.
This wait shouldn't be too long, though. No more Interferon treatments for you. All orals will get the job done and you really will SVR next time. Stay strong, buddy.
Matt Chris said
Jul 30, 2014
Hello JLynch
So sorry that you have yet to achieve your goal, I can understand the pain. Perhaps the new Gilead combo for 24 weeks might do the trick, its what I will be going for.
Depending on your liver condition there has got to be something that will work for you in the next couple of years.
matt
JLynch30 said
Jul 30, 2014
I have failed the 12 week sovaldi/interferon/ribravin.
I hate just the way it sounds, Failed Sovaldi, Your days is comming,
we are all in this together Keep your stick on the ice. {Red Green Show}
Our tx histories are are different I know, and maybe the reason my GI feels so confident ; however, i'm obviously concerned. I'm going to take Isiscat's advice and have a 12 week Vl done thru my PCP if possible.
Onto the NEAR future John. The S/L combo is showing super results for non-responders and is ONLY 2-3 MONTHS AWAY!
Jim had excellent advice on walking in the woods, etc. Focus on staying occupied and healthy until the new stuff arrives.
This sucks big time and I am very sorry you are going through it. I am just starting now to come out of my post treatment failure funk. Didn't feel myself for the longest time, but I was doing the stinky incevik combo which was very hard on my system. I have heard the sovaldi/olysio combo has much better SVR rates for us non responders And can be used after our types of treatments failed after a few months to rid oneself of the residual RIBA crapola. as for maintenance best thing to do is eat clean and take milk thistle (Not sure how much good milk thistle does, but it makes me feel like I'm doing something), No fatty foods and as much exercise as you can fit in to fight fatigue.
I'm feeling much better now almost 5 months post failure and have started to get hopeful again after looking at all that is on the horizon for us. I watched a show on YouTube where a specialist was talking about the new treatments and she said within the next ten years, hep c will be A thing of the past....
Hi John.
I would rest up and drink a lot of water. Try to slowly start to exercise a little at a time. Maybe go for a walk every day if possible and slowly increase the time. A walk in the woods is best if that is an option.
Mentally, when I failed triple tx, I just tried to focus on the fact that my liver got a little break and that I was not done trying. That I would be ready for the next time. I was grateful for the chance I had to try and get rid of it. Not everybody gets a chance. Stay the course John, your day will come.
ps I wish you could have done without the interferon. maybe you explained why already. I apologize if you did or even if you know why.
I would assume it's Gilead trying anything except a partnership with BMS. Anyway......
Thank you - in your case it looks great because you have not used interferon before!
I agree with Isis now about checking for. IL28 B or other possible flags that might hinder tx. Personally, I think too many professionals are relying on the 92% cure rate without giving it a second thought. That was the opinion of
my GI anyway who doesnt think it necessary to check my VL until the 6 month mark. I really thought this tx would be potent enough.
Try to stay strong John. I have no experience but the thought of it shakes me. I'm not sure I could be as strong as you are now, but you are taking the right approach by looking forward to the next step.
My hopes are with you and others here waiting for the the new combos.
John, I`m so sorry to hear this, what a huge disappointment it must be for you. Full marks for your determination though in going through another course of interferon based treatment, you should feel very proud of yourself for that.
Take it easy now for a while, nurture yourself physically and emotionally until the next and final round.
Sending all very best wishes, Jill
Sorry to hear the treatment failed Lynch
I had my share I'm happy to you you want to move on . As you know the needle less cures are just about here. I'm on the bus with you Mugsy Hope to see you all at the bus stop
BS
i WAS UNDETECTED FROM WEEK 4 TO 12. 5 weeks after I had labs and it was 8 million. alt/ast sky hi. Any maintenance suggestions while I wait?
Disappointing news. I am so sorry. So now you're waiting for the "new treatment bus" with the rest of us. By Springtime, we will light this board up with SVR reports.
:( sorry John, what happend exactly while you were on sov/rib/peg tx?
maybe Ledipasvir/Sovaldi combo will be one for ya?
Best
Sorry to hear this John.
Next one will be no needles. Talking about herbalists I just got an e-mail from Lloyd Wright he says he misses me.
Thank you all so much for the support. I gave myself an hour of self pity and now I must move on. I have to avoid my own mind telling me to look up every Chinese herbalist in los angeles. Like Malcolm said (my mentor), give it a break. there is a huge hep c meeting september 11th and my doctor will know then - October 10th is the next target date.
I am going to pay out of pocket for fiboscan as my insurance does not cover it yet. It is worth 350 to see what is going on.
Thanks again.
Still here cheering for u!!! keep the faith. heart is sunk & this is only temporary. know that!!! ur friend Taz
I know the feeling of a failed treatment. I have had it twice with the interferon and riba and when I had it, there were no new treatments available except the Incevik and my ins would not pay for it because it wasn't suggested for g4. The blessing is that there are new meds coming down the line soon and you will have another opportunity. Keep the faith brother!
Your sister in the fight.
John,
This is only a minor set back. Keep fighting the good fight. We're all here fighting with you.
-Rob
Sorry to hear this news John. I'm pretty new here and just started TX, 1st time. I'm scared to death of failing once. I can't imagine 5 fails. But as has already been posted, the 100% SVR - w/ no Inter. is just around the corner.
You are in my prayers.
John, I am very sorry to hear this news as well. I just hate hearing this. I'm keeping you in my thoughts and prayers!
John, I of course concur with all the preceding comments about this setback. I believe we are tantalizingly close to a 100% "cure", but unfortunately as you can attest, not quite there yet. The good news is that the next DAAs are just weeks away, and you will no longer have to suffer with Interferon as Malcolm stated. Like Matt, Greg and others, your time will be here soon!
John
Sorry to hear this John. Believe me I DO know some of what you are going thru. As with you I'm on the wait and wonder? Sometimes it is very difficult to understand. Perhaps there is no understanding it? Just hope we get another opportunity. Be well sir.
hey jl sooooo sorry im on the same treatment an im testing negative for the hep c after 7 weeks but I have to continue then come back in 6 months an see if it came back .is that what happened toyou? an im very sorry for you I have been very sick an know what you are going through what is your geno? mine is 3
Hey John,
Sorry to hear your news as well. There have been a few others with similar results and it's never easy to hear those reports, I don't care who you are. Give yourself sometime to recoup and make plans for the final assault this fall or shortly thereafter. Hang in there buddy....
Tig
Hi John,
I'm really sorry you had to go through that again. It's like a kick in the guts. No more Interferon for you.
You know the next time will work. Whether it takes 6 months or a year doesn't matter. Take it easy buddy.
Some people just are not Interferon sensitive. Usually they have a TT or CT IL28b allele. And, Sovaldi needs a good second (or perhaps a third depending on the treatment and its duration).
I don't know why all docs don't check the IL28B before Interferon tx and really think about whether they want to continue putting people on the same tx over and over again. Especially when there are other options so close.
-- Edited by Isiscat2011 on Thursday 31st of July 2014 12:44:03 AM
I am shocked to hear that the sovaldi/interferon/ribravin regimen failed , so sorry as you must be very disappointed. Hopefully one of the other new tx will do the job for you.
Tim
Well, I'm just going to say what we might all be thinking. I'm afraid the real world Sovaldi isn't looking quite as promising as the hype at the moment.
I'm so sorry, JLynch. It is especially heartbreaking when someone has repeatedly given it their all. I know you must be feeling so disappointed.
This wait shouldn't be too long, though. No more Interferon treatments for you. All orals will get the job done and you really will SVR next time. Stay strong, buddy.
Hello JLynch
So sorry that you have yet to achieve your goal, I can understand the pain. Perhaps the new Gilead combo for 24 weeks might do the trick, its what I will be going for.
Depending on your liver condition there has got to be something that will work for you in the next couple of years.
matt
I have failed the 12 week sovaldi/interferon/ribravin.
The waiting begins....