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Post Info TOPIC: Forum abbreviations
Tig


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RE: Forum abbreviations
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Hi Trudy,

I'm not sure why you couldn't delete that. If you want to repost it in the desired location, go ahead and I will delete this copy. Better to avoid taking this section off topic.

Malcolm may miss this, so I want you to review one of the posts he commented in. He is quite knowledgeable on this and has spoken on it several times. Try the search function above, a keyword or two will provide you with the discussions we've had on the forum. If I can help, let me know...

Fibrosis + Regression



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ   Lab Ref. Ranges

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Malcolm, How do you get to be an 'ex-cirrhotic' ? The reason I ask is because I was taught that chirrosis is scarring of the hepatic tissue which is permanent. Also I am 'borderline chirrosis' so if what you say is true... I am personally invested.
Unless I'm way off base ........
If you wouldn't mind clarifying for me, I would greatly appreciate it
Trudylookinglass

 

sorry for posting under abbreviations!

tried to edit/delete and put elsewhere to no avail



-- Edited by Trudylookinglass on Wednesday 30th of November 2016 10:18:46 PM

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HCV Dx 1993 Compensated Cirrhosis dx 2016 GT4 TX 12 Wks tx  (ombitasvir, paritaprevir, ritonavir tablets) combined with Ribavirin (-)HCV (+)AIH and other autoimmune conditions...

Tig


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Hi John,

Welcome to the forum! You'll find lots of good information and good people here. It's a good idea to introduce yourself by starting a new thread in this section (New Members) and tell us about yourself. People will be able to respond to you there.

Here's some directions to set up your signature and more abbreviations that we share. If you use the search function at the top center of the page, as well as the homepage index, you can find many of our discussions. If you have any questions please ask.

Signature/Abbreviations



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ   Lab Ref. Ranges

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New to the group looking to fill my head with some information have had Hep C for over 40 years. Thanks

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John Washington


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I`m bringing this post up again for the benefit of all our new members who might be struggling to make sense of the abbreviations we use here.  Just scroll down to the start of the thread. 

Many thanks again to Malcolm (mallani) for compiling this very comprehensive list of forum and medical abbreviations.  smile

 

(I`m keeping this as a `closed` post, but if anyone has any questions regarding anything on this list, or anything you can`t find on the list, please feel free to start a new topic.  Thanks!)



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Jill 

(68 yo, lives in UK)

Was Gen 3a, 

24wks Peg/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Got it; thank you. :)



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OMJ - started treatment April 25, 2014

Prior to treatment VL 14 million. Liver Levels Abnormal but under 70.

Sovaldi/Olysio

VL: SOT = 14 million.    SOT +2 weeks = 28

AST/ALT: Normal

Week # 7 = UND

Tig


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Go down to the bottom of this thread where Mallani (Malcolm) posted his list. The one I left the link to is an addition to his. EOT stands for "End of Treatment".

Tig



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ   Lab Ref. Ranges

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Sorry Tig but I didn't see EOT in http://www.hcvguidelines.org/full-report/methods-table-3-commonly-used-abbreviations-and-their-expansions

 

Am i losing my head. sorry.



__________________

OMJ - started treatment April 25, 2014

Prior to treatment VL 14 million. Liver Levels Abnormal but under 70.

Sovaldi/Olysio

VL: SOT = 14 million.    SOT +2 weeks = 28

AST/ALT: Normal

Week # 7 = UND



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Thank you!

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OMJ - started treatment April 25, 2014

Prior to treatment VL 14 million. Liver Levels Abnormal but under 70.

Sovaldi/Olysio

VL: SOT = 14 million.    SOT +2 weeks = 28

AST/ALT: Normal

Week # 7 = UND

Tig


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I was reviewing this website and came across this information. Thought it might be a good update/addition to Malcolm's already extensive list.

http://www.hcvguidelines.org/full-report/methods-table-3-commonly-used-abbreviations-and-their-expansions

Tig



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ   Lab Ref. Ranges

Signature Line Set Up/Abbreviations   Payment Assistance

 

Tig


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Hello New Members,

I wanted to be sure you have all been pointed to this excellent thread containing all the abbreviations we use here on the forum and then some. Our esteemed member Malcolm "Mallani" put this together for us and it was made a sticky so it will always be available. But those that have missed it on our homepage directory should take a look. It's a valuable piece of information! I like to point it out to the new folks here, just in case they missed it. We use these abbreviations all the time and forget at times that some of you don't know them yet. So now you know!!

Tig

Forum Abbreviations:  http://hepcfriends.activeboard.com/t51085702/forum-abbreviations/



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ   Lab Ref. Ranges

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Thanks Malcolm, i refer to this often.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Whoops! Used English-Australian terminology. Apologies to our US members. Drop the 'a' from haemoglobin etc and ECG is EKG.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm



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Here are some useful Forum Abbreviations:

A0-4: Used in liver biopsies to grade inflammation, where A0 is normal, and A4 is severe inflammation

AFP: alphafetoprotein- a tumour marker. normal range 0-12 ug/L. Often used for HCC diagnosis.

AHC: acute hepatitis C

ALP: alkaline phosphatase, a liver function test. normal range 35-110 U/L

ALT: alanine aminotransferase ( formerly SGPT) , liver enzyme. normal range 5-40 U/L

ANA: antinuclear antibody- Measures autoimmune antibodies. Normal range is up to 1:160 dilution. Used in diagnosing autoimmune diseases from HCV or Rx.

AST: aspartate aminotransferase ( formerly SGOT), liver enzyme. normal range 10-40 U/L

BID or BD: twice daily

BMI: body mass index

BMS: Bristol- Myers Squibb, manufacturer of Daclatasvir and other DAA's.

BOC or Bocep: boceprevir = victrelis.  A  DAA, one of the early antiproteases manufactured by Merck (discontinued)

BUN: blood urea nitrogen- normal range 3.5-9.0 mmol/L

BX or Bx: biopsy

CABG: coronary artery bypass graft

CBC: complete blood count

CCP antibodies: measures anti-Cyclic Citrullinated Peptide antibodies. A specific test for rheumatoid arthritis, or other undetermined arthritis.  Normal range <3

CFS: chronic fatigue syndrome- may occur in CHC and/or post treatment

CHC: chronic hepatitis C

COPD or COAD: chronic obstructive pulmonary ( or airways) disease

CRP : C-reactive protein. Measures inflammation in the body. Normal range <10. May be raised in HCV, particularly where there in on-going fibrosis

CT: computed tomography

DAA: Direct acting antiviral. Medications targeted at specific steps within the HCV life cycle (see Hep C News section)

Dak: Daklinza, DAA manufactured by Bristol-Myers Squibb Co

Das: Dasabuvir. componentr of Viekera Pak

DNA: deoxyribonucleic acid

DTT: difficult to treat

Dx: diagnosis

ECG- EKG: electrocardiogram

Elba: Elbasvir. component of Zepatier by Merck & Co.Inc

ELISA: enzyme-linked immunosorbent assay- measures HCV antibodies

ENA:  extractable nuclear antigen antibodies. +ve in Rheumatoid Arthritis or other autoimmune disorders associated with HCV.

 ER: emergency room

 EOT: end of treatment

 Epc: Epclusa, DAA manufactured by Gilead Sciences

 EPO: erythropoietin (procrit)- stimulates red blood cell production

 ESR:  erythrocyte sedimentation rate. Non-specific measure of inflammation in the body. Normal range is age dependent, but should be <18

 ESLD: end stage liver disease- usually decompensated cirrhosis

 EVR: early virological response to treatment- usually undetected virus at week 8 or 12

 F0-4: liver fibrosis stage where F0 is normal and F4 is cirrhosis

 FBC: full blood count- same as CBC

 Geno or GT: genotype - identification of the strain of HCV  i.e. 1a, 1b, 2,3,4,5,6.

 GGT: gamma glutamyl transpeptidase- liver enzyme. normal range 5-50 U/L

 GI: gastrointestinal- may mean gastroenterologist

 Gilead: Gilead Sciences, pharmaceutical manufacturer of Sovaldi  Harvoni  Epclusa and Vosevi

 GTT: glucose tolerance test- most accurate blood test to diagnose diabetes

 Graz: Grazoprevir. component of Zepatier by Merck & Co. Inc

 Har: Harvoni - DAA manufactured by Gilead

 HAV: hepatitis A virus, or Hepatitis A disease

 HBV: hepatitis B virus, or Hepatitis B disease.

 Hb or HGB: haemoglobin. normal range 125- 175 g/L

 HCC: hepatocellular carcinoma- liver cancer

 HCC-CC:  hepatocellular carcinoma and cholangiocarcinoma combined

 HCV: hepatitis C virus- may mean chronic hepatitis C

 HCV-RNA: hepatitis C virus ribonucleic acid- number of viral particles

 HepC: another way of saying chronic hepatitis C

 HIV: human immunodeficiency virus

 Holkira Pak: DAA manufactured by AbbVie Corporation (Canada)(also see Viekira Pak)

 HVL: high viral load- > 800,000 i.u.

 Hx: history

 Inter. or IFN: interferon- may be alpha 2a or 2b

 IR: insulin resistance-common in HCV- may indicate diabetes

 I.U.: international unit- in viral load, 1 i.u.= 2.5 viral particles

 IV: intravenous

 Led: Ledipasvir, component of Harvoni

 LDH: lactate dehydrogenase- a liver function test. normal range 120-250 U/L

 LFT: liver function test

 LiPA: Line Probe Assay, a type of sensitive HCV Genotype test

 LLQ: lower limit of quantification (also see 'QUANT')

 LLN: lower limit of normal

 Log.: a method of expressing viral load, where log1= 1million i.u.

 LVL: low viral load-<400,000 i.u.

 Mav: Mavyret/Maviret DAA manufactured by AbbVie

 MCV: mean corpuscular volume- size of red blood cells. normal range 80-100 fL

 ME: myalgic encephalomyelitis- similar to CFS

 MELD: model for end-stage liver disease - indicator of overall liver health

 MI: myocardial infarction

 MS: multiple sclerosis- an auto immune inflammatory disease of nerve sheaths .

 MRI: magnetic resonance imaging

 NAFLD or NASH: nonalcoholic fatty liver disease- fatty liver

 Neup: neupogen- stimulates white blood cell production

 Neut: neutrophils-white blood cells that fight infection. normal range 1.5-6.5 10^9/L

 NS-3 and NS-5: Nonstructural sites on the HCV genome, which can be blocked by a DAA. . NS-3 contains a protease, and NS-5B contains a polymerase. NS-5A is the regulatory complex.

 Omb: Ombitasvir. Component of Viekira Pak

 PCR: polymerase chain reaction- may mean viral load test

 PEG: polyethylene glycol- 'pegylation'- . Often refers to pegylated interferon (one injection/ week)

 PegIFN: pegylated interferon- alpha 2a or 2b, or gamma.

 PI: protease inhibitor

 Plat: platelets-required for blood clotting. normal range 150-400 10^9/L

 PSA: prostate specific antigen- blood tumour marker for prostate cancer- normal range 0-4.5 ug/L

 QUAL: qualitative- refers to a PCR test for HCV RNA, that may be +ve or -ve.

 QUANT: quantitative- refers to a HCV RNA test that gives a number of viral particles (down to the limit of quantification)

 RAV: Resistance-Associated Variant. Drug resistant mutation of HCV to a class of DAA's.

 RBC or RCC: red blood cell count. normal range 4.2-6.5 10^12/L

 RIBA: recombinant immunoblot assay- accurate test for HCV antibodies

 Riba or RVN: ribavirin

 RGT: response guided therapy- treatment based on viral load results

 RNA: ribonucleic acid- the genetic makeup of the HCV

 RVR: rapid virological response- undetected virus at 4 weeks.

 eRVR or sRVR: extended or sustained RVR- undetected virus at 12 or 24 weeks

 Rx: treatment- may mean prescription

 Sc or SC: subcutaneous - eg where interferon is injected

 SNP: single nucleotide polymorphism. Refers to protein complexes near genes.

 SOC: standard of care

 Sof: Sofosbuvir (Sovaldi), DAA manufactured by Gilead

 SOT: start of treatment

 Sov: see Sof

 Sc or SC: subcutaneous- where interferon is injected

 SVR: sustained virological response- undetected virus 12 - 24 weeks post treatment

 Sx: side effects or symptoms

Tech: Technivie, DAA manufactured by Abbvie 

 TID or TDS: three times a day

 TMA: transcription mediated amplication- a sensitive viral load test

 TSH: throid stimulating hormone (thyrotropin)- regulates thyroid gland.  normal range 0.3-4.0 mU/L

 TVR or Telap: telaprevir = incivek

 Tx: treatment- may mean therapy

 Undet. or UND: undetected, as in viral load

 ULN: upper limit of normal

 US: ultrasound

 WBC or WCC: white blood cell count- range 3.5-10 10^9/L

 Vel: Velpatasvir. Component of Epclusa

 Viekira Pak/Holkira Pak: DAA Tx manufactured by AbbVie pharmaceuticals

 VL: viral load- 1 i.u./ml= 2.5 viral particles/ml

 Vosevi: DAA manufactured by Gilead

 Vox: Voxilaprevir, component of Vosevi manufactured by Gilead

 VR: virological response- to treatment

 Zep: Zepatier. DAA manufactured by Merck pharmaceuticals

 

*N.B. Where normal ranges are given, these may vary between the sexes, and from lab. to lab. Check which units your lab. uses. 

 -- Updated by wmlj1960 on Saturday 7th of October 2017 01:53:25 AM



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm

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