Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Post Info TOPIC: Started harvoni 5/1/18-my thread :D


Senior Member

Status: Offline
Posts: 370
Date:
RE: Started harvoni 5/1/18-my thread :D
Permalink  
 


hi tig, i agree ... this confirm of undetected is as good as cured

i look forward to my†SVR12 with confidence since my liver panel a few weeks ago shows my liver is still happy

i hope you are having fun but getting some rest as well with the little ones wearing you out



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hi C, by the time i started tx those ppl had moved on from my work place but they were def in my mind.

one is still there but he also has other non-harvoni related probs. ; but it was good to see him now and then.

the bosses had seen 2 of them during their tx and were aware of the ups and downs.

yes, i continue to have some very nice days , i can now take some antihistamine .. just a bit of dust on my finger and lick really; but it gives my body just enough to help me. Kind of like holistic stuff that you only need a bit of. it's not in my mind cos i notice when i don't get my dust. hahahaha

so, yea... one month after tx things started going in a calmer, better way for me

i still need plenty of rest and off my feet but i am thrilled with my progress

hubs still had other probs that he must see dr's for now. rhumatologist is next cos his aches and pains are pretty much constant†cry†. he's been off tx 7months now and it's not as bad but still daily pain.

i count my blessings and praise my mind for for my positive self talk ; since my last labs showed good liver panel results i too am positive that the virus took the hint and left without much resistance. it was time, the free ride was over†biggrin

5



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

Hey 5,

Nice for your string of good days - you do SO MUCH deserve so many more of those (and they will come, I am sure), good news on your hubby's SVR24, really good. You will be next in the SVR line-up in just a couple months what with your SVR12 date coming up, but we all know, in our guts and hearts, that you have already been sustaining it - I just know it! It's the family plan, the whole dang household deal, everyone cured, no virus left standing.†wink

How is work going? You said some of the folks you work with were familiar with what you were going through, because they too, themselves went trhough treatment? - did they share what their drugs were, or what it was like for them? Did you work with any of them while they were going through treatment? Just curious. I thought that good that you had others around you (aside from your dear hubby) who went through it and to whom you could relate. Did your co-workers experiences help you at all you think?††C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

WOOHOO!! Thatís fantastic news! That is absolute proof that his SVR is strong. He can start breathing again, lol! I remember getting my 6 month VL and was sweating it. Honestly, we sweat them all, but SVR12 is all we need to confirm success, but each one after the fact, is always golden. Itís my favorite word these days, ĒUndetectedĒ...



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

GOOD NEWS ABOUT HUBBY!!† UNDECTECTED biggrinbiggrinbiggrinAT 7 MONTHS POST TX



-- Edited by 5-1-18 on Wednesday 15th of August 2018 09:00:12 AM

__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hooodie†biggrinbiggrinbiggrin. i am def having a string of good days over here. one month PT {post treatment}



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Online
Posts: 112
Date:
Permalink  
 

Awesome! High five, 5!!



__________________

F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1, VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God.†



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

AFP-L3% result is below the detection limit of the assay. RefRange:0.0-9.9

AFP,Serum†1.6†normal:†[ReferenceRange]0.0-8.0†ng/mL



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

thank you hoodie and canuck . i even woke up ok to day too; but taking it easy anyway†biggrinbiggrinbiggrin



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

5,

Go ahead and laugh at me, but I "flunked" sinus lavage (yuck) miserably! Pushed to do it by an allergist I saw not long ago, got all the expensive accutrements of lavaging oneself with saline and steroids, and never got the hang of it. Tried and tried, but it was something akin to water boarding or drowning in your own bathroom. Called her back and she offerred me a nice neat tidy expensive (not as good a method according to her) fancy/pansy simple steroid nasal spray instead! We bargained for middle ground, I devised my own inexpensive saline, used up the expensive steroid concentrate she originally gave me, and used it as a nasal spray (versus) as a "sinus lavage". Together we just had to juggle and adjust how much steroid to mix with the saline (same ingredients) when used in the nasal spray mode instead of the sinus lavage mode.

When I was initially in search of sterile saline, I don;t know how many pharmacies I went to, saline not to be found!, (what?!) and when it was... what highway robbery that was - it's JUST salt water fer kripes sakes, not prohibited, restricted or rare, like oxicodone or gold fer cripes sakes! Why is saline not a cheap/common from-the-shelf item to be found at ANY pharmacy!†

So my remedial course on nasal sprays has now kinda petered out too, I guess I would rather put up with my symptoms, which really are not bad now. We'll see.

†In retrospect ... are you thinking that one-off migraine-like thing had maybe more to do with the sinuses/inner ear thing happening versus than just an out-of-the-blue migraine?

My fingers are crossed for you, that the sinus/inner ear thing will be silenced now. Only nice and quiet, and calm and good should be the things in store for you after all your hard work. Things will get and go better - you'll see. A little time, and things will start to right themsleves. Glad you are better than you were!†smile†C.

Later, C.†



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Online
Posts: 112
Date:
Permalink  
 

Glad youre feeling good 5! Stay well my friend!



__________________

F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1, VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God.†



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

today i actually feel alive and good. left ear sill singing a little song, but the right ear gives me hope that all will be well soon. So either i get to feel good or this is the giddyness before the sinus infection tries to blow up again..... of course i am looking forward to a easier this being a better month than last month.... virus free and feeling good today

i just used the neo up da nose after i quit the AB's to give my sinus something to suck on.hahaha, and it helped the dryness pain

i use the nasal crom which is:

Cromolyn Sodium†is the†sodium†salt form of†cromolyn, a mast cell stabilizer with anti-inflammatory activity.†Cromolyn sodium†probably interferes with the antigen-stimulated†calcium†transport across the mast cell membrane, thereby inhibiting mast cell release of†histamine, leukotrienes, and other substances that cause hypersensitivity reactions.†Cromolyn sodium†also inhibits eosinophil chemotaxis.

so, that is my saline solution every day. also i have used mineral oil up my nose for dryness.† just a dab on a qtip of anything really.

i can't see adding more salt to my system by putting it in my nose so i use the distilled water in this alkalol device [can't use that cos allergies to the stuff]. then put just a little in my nose to flush up, rarely over. Then spray with nasal crom and dab with moisture

i'm not big on this flushing the nose thing....... haha†biggrinbiggrinbiggrin

i'm thankful my work week is over and that the last 3 days went easy on me. wow.

5



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

thanks friends†smile†. i already feel much better today.†

i was taking a dose of probiotics 12 hrs after my dose , i stopped that too when the **** hit the fan........so to speak.hahaha

i now swear it was a virus; i have never had that kind of sickness with AB's before.

so.... now to just stay well and not catch anything else or have weird things going on in my head.hahaha .

today i got my afp back and no flags.... it's hard for me to read that particular lab report but will get another on wednesday and i'll post that...... but i'm happy with "no flags".†

ahhhhhhhhhhhhhhh



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

Agree with Tig, probiotic (yogurt/sourcream, etc., etc., whatever source you prefer to consume/can consume), as long as you are getting enough good bacteria in your gut (or back into your gut as the case may be) - before, during and after systemic antibiotic use. I think it is good idea to do this (just on principal) when on antibiotics, as we always have to keepin mind the destruction of a sizable amount your good bacteria that may happen as well. Maybe you did just unfortunately have the gastric fluey thing the others did, or, maybe it was your antibiotics robbing your gut of balancing bacteria, and thus either (or both), propelling you to spend time doodoo-ing the loo.††

Hydration/flushing of nasal/sinus mucous membranes (if required) should alway be saline, not just tap water, not distilled water. Saline is as close to and as compatible as can be with the bodies cell make-up, saline is best to use directly on mucous membrane. You can google up how to make up your own boiled/sterilized saline supply (if you are flushing your sinuses/nose a lot for some reason) - but the whole idea of mucous membranes is that they produce this wonderful stuff - called mucous, which, when in balance, works great all on it's own for lubicating, hydrating and protecting you from harming substances, and preventing things from traversing your respiratory tracts - wonderful stuff mucous is, when you have just the right amount of it, at the right viscosity and it's doing it's job!† Agree with Hoodie, if one feels they have to use some kind of hydration/moisturizer, soothing barrier or de-dydration preventer ointment up in the nasal mucous membranes because things are out of natural balance/acutely dry - then something like inert vaseline can be used (if necessary) after a flush and re-hydration with a nasal saline lavage, for comfort/relief, a small simple swipe of swipe of plain clean vaseline up the nares might work just fine for you versus using a polysporin antibiotic based ointment (the active ingredients in the polysporin may not really be called for, if all you are after is soothing comfort).

Always best to keep it simple, I think, starting out trying the least intrusive/inert remedies and treatments that provide the relief or effect you are looking for.†

I don't have much experience using coconut oil on mucous membrane in any kind of ongoing fashion, or, at all, so I can't speak to that, have only ever put coconut oil it on my skin, brushed my teeth with it once!, and, I have eaten a fair bit of it!†

Some stewardess gets some credit for this dangerous but effectively soothing trick ... (never a sole treatment) ... for ear popping (OR ear infection, etc., an inner ear problem) - dip a clean washcloth in boiling water and wring out with thongs or squeeze between plates or whatever until NOT dripping, quickly stuff/jam the steaming/boiling hot damp/wet cloth in the bottom of a tall tumbler (use a tumbler large enough to keep the boiling hot cloth stuffed securely in the bottom end of of the tumbler so the hot washcloth never touches you, wring the cloth out enough so that hot water will never drip back/run back on you, tilt the hot end of the cup ever so slightly downward, just in case). Completely encircle/cover over your ear area with the big open end of the cup, keeping the tumbler sideways/horizontal and let the heat/steam transfer across the cup to the ear for at least 10 mins or until you need to re-wet the cloth with boiling water again to make/keep this tumbler a steam chamber. This can aid greatly blocked, poppin ears, perhaps assist in opening eustacian tubes, soften/move wax, and help speed up lymph and blood circulation to assist curing and soothing congested inner ear things (or outer ear things for that matter). A few or several times a day, for 10-15 mins at a time or even† 30 mins, can really feel soothing when you have a ear thing going on.

Alternately, just some nice hot/warm/moist compressing can be done directly to the side of your head/neck/ear area on the affected side,† instead of doing the tumbler steam chamber method. That works good too.

That's all I have in my medicine cabinet repertoire.†wink†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Online
Posts: 112
Date:
Permalink  
 

Hi 5! I used to use Nasal Crom all the time it worked so good for my allergies! Forgot all about that stuff but next spring Im gonna stock up. Thanks for the reminder. I also used a NeilMed squirt bottle irrigator thingie that was easier for me to navigate than the NetiPot. Great minds think alike †

Can you try coconut oil instead of neosporin for a topical nasal moisturizer? Neosporin often causes more harm than good for people who have a sensitivity to it (namely me and many other people). Coconut oil has mild antiviral properties as well. My doc told me to use plain Vaseline on wounds because so many of his patients cannot tolerate neosporin. †Sorry you were struggling so hard with the ABX and stomach flu. †

Glad to hear youre starting to feel better. Personally I love the CVS silver wound healing gel for wounds.†

Off to work, see ya later feel better soon



-- Edited by Hoodietree on Monday 30th of July 2018 11:33:05 AM



-- Edited by Hoodietree on Monday 30th of July 2018 11:33:31 AM

__________________

F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1, VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God.†

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

I hope you get back to 100% soon. Youíve had a rough patch to get through, poor thing! The fires are so hard on respiration, especially for those with some pre existing conditions. Have you tried eating yogurt or adding probiotics when you try the antibiotics? The heartburn is coming from the AB destroying your gut bacteria. I imagine youíve tried just about everything. Iím going to remain hopeful that with SVR, youíll start witnessing improvements in many areas. Iím keeping my fingers crossed! I admire your strength...†



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

i should have my afp's by monday afternoon

and my stomach,liver and galbladder feel so fine now after the stomach virus evacuated my guts.biggrin



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

Hoodietree wrote:

Congrats 5!!†


†oh hoodie, this is my thread i do most of my blogging on about my journey during and after

i'm def feeling much better and am thinking i had a stomach virus... haven't had one of those in decades.



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

canuck, i have a long life history of sinus infections and the last cpl years the ears have jumped on the band wagon. she looks into my ear with her scope and sees something that seems 'contracted'. AND. i have a hissing sound in my ears; normally that never stays around this long [ but ears are viral and can be bacterial too so i'm still hopeful i won't need more meds]. i'll def keep an ear on it

i have always been cured by 2 doses of zpack [azithromycin] , but for some reason she wanted to use this which is more specific to sinus/ear infections...... i could have said "i'm afraid to try something else', but couldn't have imagined this reaction.... i can't take amoxycyllin or tetracycline or doxycycleine† due to dizzyness; but can take some others. some give me bad heartburn.

i was doing good till the stomach thing hit, and like i said it could have been a coincidence but i wasn't gonna gamble on it.† i took 8 out of 14 and maybe that virus took it all down the toilet bowl with it.

i hope that was enough too..... i didn't even see the dr, i'm so sick of that right now. but i seem to be on the good side of the whole ordeal so keeping my fingers crossed.

i had taken a small bit of claritin antihistamine and half a pill of ibuprophen for 2-3 days in a row [normally that's all i can do before my system over loads].† so i thot that was all part of the sickness too.

i just hope that's all behind me now and that my bod can regain health like it wants to.

i use a spray that is chromalym sodium, nasal crom to help with the histamine and rinsing my sinus with the nettie type pot [brand new]. a cpl times i used tap water till i read how that can cause problems so started the distilled. OF COURSE† i thot i gave myself a weird parasite hahaha, but our tap water isn't the worse and it was only a cpl times

i've been using neosporin antbiotic ointment into my nostrils to help with the dryness. that dryness was causing much of the pain..... duh. so, maybe that helped everything out too.

there's lots of fires around here that haven't helped [and those poor ppl right in the thick of it ].

but like i said, i believe i am on the other side of this mess and passed this test well.



-- Edited by 5-1-18 on Monday 30th of July 2018 07:32:09 AM

__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

ok , so here's the update on the antibiotic drama.

i may have had a stomach virus! it's going around work and i have never been that sick on any medication before...... curled up in a ball feeling liver,galbladder stomach discomfort like nothing else ......wow

then the runs for 3 days and feeling like a train hit me.†

finally today i feel the most better than in days and days. my ears are still messed up but the headache is gone and most of the dizzyness.......

but i quit the antibiotics, it's not like that couldn't be addressed again if i don't feel good. i wasn't going to take a chance† at all.

so..... lucky me. a migraine , sinus/ear infection and stomach flu in the month after my harvoni, oh yea† and my complexion was right there raging too.

let us hope that in my second month virus free i more good times and healthy days

and the best news is i have my happy life is good mood back. that virus pretty much knocked that right out of me for a few days. even the migraine wasn't as bad as that.



-- Edited by 5-1-18 on Monday 30th of July 2018 07:30:26 AM

__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

Hey 5,

So this "cindifer" they put you on?, have you taken that particular antibiotic before?, how many days were you supposed to take them, and how many days did you end up taking them? Maybe you managed to get a sufficient number of days of the planned course into you to successfully kill off any organism growing in your sinuses, before you had to quit them? What was it that happened that made you to have to stop taking them?

Did you get to see any doc for suggestions/opinions/advice, about discontinuing your course, or perhaps starting a dif. antibiotic?, or ... what was decided would be the best plan for you now? I was never quite clear on your answer to my prior questions ... when they looked in your ears (prior) did they see red, suspectedly involved/inflammed ear canals, and or ear drums?? If there were any visable signs in your ears before, have they had another look now? Were you having any pain, clicking, popping, muffled noises in your ears before?††

Had any of the sinus/inner ear things (your symptoms) seemed to be improving while you were on the course?

Seems to me the only big stand-out sign and symptoms you were fighting with (just prior to your doc examing you† and saying it was sinus/inner ear related and giving you antibiotics) was that weird "migraine" type headache you had?

If you are prone to "seasonall" type allergy things happening to you about twice per year - what things do you try to do for it, to prevent things from getting the better of you? Did you say previously you do these nasal flushes, or decongestants or anti-histamines??

Let us know how the sinus thing feels now.††confuse† C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Guru

Status: Offline
Posts: 826
Date:
Permalink  
 

TA DAH!!! such good news,

except the sinus thing that always sucks. Hope you will be feeling better and better everyday.

BB, Iris



__________________

in the silence of the woods, you will not be alone- Chief Seattle

59 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naÔve....UNTIL 7-01-18† !!!! started Harvoni 12 weeks. :)



Senior Member

Status: Online
Posts: 112
Date:
Permalink  
 

Congrats 5!!†



__________________

F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1, VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God.†

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

Good news, 5! I expected all to be in nice shape, just as your VL will be. Well done! The liver is an amazing thing, especially when itís working right. Iím amazed that it can function so well, even when we have been so sick. Itís a tough ol piece of meat! Iím hanging on the edge of my seat, just waiting for your undetected VL. Get it quick, I might end up on the floor, lol!

smilewinksmile



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 149
Date:
Permalink  
 

Fantastic news 5 thumbsup.gif You must be thrilled for sure and getting an extra look at the liver function....what a bonus clap.gif



__________________

65/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment

Gen 3a Fibroscan 8.6 Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

liver enzymes still normal†biggrinbiggrinbiggrin

my family dr included them in my recent blood work..... and hey, even my hdl cholesterol is in a good range after years of struggle with it......

my liver is happy and it shows , no viral load but i know the labs would be hinting at something being off....... so yea, i'm feeling groovey

i'm glad she included the liver panel for me; i have the best fam.doc. OH and my b12 is normal too so i'm thinking that was also part of the virus complications.



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hi C and stl,

i get these infections twice a year..... and july is the month for one of them . hopefully my body will be able to beat them back easier as i heal from the liver mess

i got the extra time off from work becos i was still so drained from the harvoni so that is cool. i go back on monday.

it's cindifer 300mg. 2 capsules a day, for sinus and ear and yes there was some puckering in there.hahahaha, she didn't say ear drum so that's good . together or apart. toay i split them up up by† a few hours but tomorrow i will take them both at bedtime with my oatmeal [no vinegar for now].†

oh canuck that is so sad all you went thru at eot . i guess our body has to realign itself after decades of carrying the virus. and also detoxing from the meds.

yea, i can't wait to find out what the doc ordered for me.....normally i check it all out but i was too tired this morning.

it usually takes a week for them to post onto the website but the doctor's nurse always calls me as soon as they get it to let me know if i'm high or low.

now i get to call my boss and let her know i'm on medical again.....but she understands this is a hard time for me.



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 149
Date:
Permalink  
 

Oh 5 you poor thing. cry.gif These irks and quirks are certainly shooting in your direction. So now you have swapped your antis (antivirals - antibiotics) and the little pill box still has a use in life. Rest up, keep hydrated. Hope you are feeling better soon. Your sun.gif will shine again.



__________________

65/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment

Gen 3a Fibroscan 8.6 Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

ah poop. What a bummer that it was a sinus infection, but so good you are on it, and paying good attention to these things. Too bad you have to do a course of antibiotics (I mean - i would have been so much happier if you had just not had ANY sinus trouble period) but that is the correct right call you and your doc made given the long ongoing symptoms. So is the imaging, she is right to consider further investigation just to see if there is anything else she can know to help prevent further troubles in future - ya never know unless you look, think, consider everything thoroughly. I had a spell of irksome things befall me post-cure - wierd skin things, eye and ear things, facial lumps, bumps and yucky growths - I also had to do some antibiotics of various sorts (oral, drops, ointments, gels, sigh) I just kept growing up new boil like things in my ear canals and one nasty one on my forehead, and had to keep getting them lanced. yuck, the ear things were awful painful, the forehead one was the worst, looked the worst anyway, my eye was crooked awful near swollen shut with it as well, they lanced and packed the forehead one for a while with wet daily dressing changes then slowly we drew the edges together with steri-strips to close it - you can hardly see where it was now. It was not a nice time, but not too serious either, I got over it, but it was a wierd stubborn spell i went through for a while just after cure, I think as my overall health improved post-cure, then so did all these irksome events decrease porportionately. Tig was so right ... at one point, he reminded me I was probably not drinking enough water, even though I was post-cure, and he was right, i had slacked off the water. Water intake is STILL important to me. Now, that is not the case, in your case, cuz you have always been so good in the water department. Maybe this tough long haul was just a little too long a haul for you, maybe you did need a wee bit more rest, maybe that might have helped, who knows, maybe some more time off (if it can be managed), would be a good thing to try. Wouldn't be (in my partners case), for a type A stress-boy personality, that would drive him absolutely bonkers being restricted from anything he wished he could do. Lay low, rest up, do all the things you probably already know what to do to help your sinuses, treat yourself extra good and special in some way.†

Good you had lots of bloods drawn and a repeat AFP, always good to keep an eye on everything, and nice when things just like simple labs help confirm what's up and what's not. Let us know when you know what your bloods say, until then, glad to hear you are napping/resting. Just the thing to do. smile†C.†

PS - what kind of antibiotics did you get, how many mg each, how often (1 pill twice per day you said?) and for how long. Had your (inner) ears been "popping, muffled, paining" prior, or at all? Did she say she looked and could see your drums appeared inflammed/involved? Did you discuss anti-histamines or decongestants - hot compressing your neck/ears/eustachian tube areas -increased humidity to breathe? Just nosey.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

i went to my family doctor today and she put me on antibiotics for sinus/ear infection.....and! more time off from work.

i like that i can take it easy and not have to work while my body fights this infection ; work has been way too difficult feeling like this.

after harvoni these meds should be a snap; but i am using my harvoni pill keeper since i have to take these 2 a day together or apart.

she also did lots of blood work, i didn't read it so it will be a surprise but it was 5 vials. also my AFP was done for the liver doc.

the doc says if i have another migraine she wants me to have an mri...... hmmmmmmmm, if it's dye in my veins i doubt it ,†

she's really following how the during and after harvoni stuff goes, she is getting very informed.

ok, nap time for me; looking forward to getting well from this sinus infection

5



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

Itís nice to have a caring and considerate employer. That makes treatment and your job, in general, so much easier. Big +1 for that. Home, a nice invigorating and ultimately relaxing shower and some TV down time! Good for you.

I want to comment on the nsaid fog. Itís entirely possible itís related more to the Hep and the Tx medications. Itís very common and the good news is, after SVR, you should realize great improvements during the first 6 months post Tx. I had moments when it was like a light bulb turned on and I realized I was actually remembering things easier and that odd fuzzy confusion or thought delay had let up. I hope you can enjoy that, I think you will!†smile



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

i made it 5 hours at work and the boss had mercy on me ,also i didn't get any flack for calling in. she marks it down as part of my harvoni tx..... too cool huh? wow

.....and that is why i try so hard for her

so, the nsaid fog is lifting along with the gut pain from it . and my hope is that it was the new b12, but i do have a mild headache akin to previous sinus problems.... it all seems manageable anyway.

but i came home,showered and plopped in front of the tv biggrin, feeling happy to have things managed so well all around me.

5tth



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hi tig, wow..... getting one while driving would def scare me too much.

i hope that's the only one i ever get; sure it's pretty and all...but....,well you know

it sounds so complicated when reading about them, but so many ppl get them. of course i googled celebrities with migraines.hahahaha; figure if the show must go on i should find out who's going on.

i feel well enough today; it feels like seasonal allergies and i haven't been able to control those very much.

for now i'm still focused on recovering from my harvoni and cured from hcv, at least there is something that worked for that!

i guess somewhere in the back of my mind i thot the hcv would get me so i kept working and spending money.†

so now i can revamp to saving cos i am gonna live

ok, off to the insane asylum for a few hours of work....lolol†biggrin



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

Iím glad youíre feeling better every day, 5! You go girl! Iím sorry to hear about the migraines everyone speaks of. I had some doozies of my own, but thankfully have avoided the bad ones for years. Lucky me! I still have all the precursors to them though, which is weird. I get weekly auras and those damned prism effects. They donít do much for your forward vision! Iíve had them hit me while driving, thatís a bit unnerving!

I hope youíre enjoying the time off!



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hi canuck,

i def would have panicked if it was as strong as yours....i'm sure of it!

good for me it was at work so everyone knows and want me to feel better.

funny, i had just told my boss a few hours earlier that i was almost feeling as good as before tx except for the tiredness .hahaha.....right!

and i agree, i felt i did want more time to take it easy and my body said "here ya go......." hahahahaconfuse

i only have to work 2 more days then have 3 days off so should be ok..... i'll go to bed earlier tonite and get some good sleep and wake up refreshed.

we had some stress at work during the week, plus i did over do it at home on my 3 days off..... normally no it wouldn't be too much; but on harvoni rehab time it def was.

my next 3 days off will be much easier and i'll make that so.

so cool that you don't work and that's ok with me; i'll take some of that thinking on for me sooner than later i think

yes, will chk BP and at dr's will have labs for b12, thyroid and blood sugars.

i started taking more b12 the past week so of course that is on the shelf for now ; i'm not taking any chances

just water and thyroid for now.

i hope i feel as good as i did friday, but i really haven't been sleeping well so that must add in to all of it.... i was tired after 3 hours of work, but made it till 1am when the lights wanted my attention.

it is def easier to move thru scary stuff with ppl who have walked the road. again, thankyou 5



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

I am glad you (and the good minders of your well-being - the body police) have decided you must "assume the position" and stay home, be off work and rest. It is too bad you are still struggling with feeling "better" - but I think it will start coming soon. You just need a break, a more "even keel" spell to see that there IS light at the end of the tunnel - just like STL's avatar! Feeling better is coming - it took me quite some time to start feeling better, but it did come!, sometimes huge little things occured which pleased me no end, and other things were just slow and steady and are still getting better! biggrin†This up and down business can unnerve a person, or at least it's very wearing/testing on a body and soul. But just look at what you accomplished!, you worked your way right through treatment. I didn't have to do a gall durn thing, cept get my butt to the doc when he said to, and then I had James do ALL the heavy lifting, NEVER in a million years would I have EVER been able to do what you did and work my way through treatment - you hard workers impress me alright.†

You ask about my area of expertise?? - absolutely nothing, THAT's what I do best!, but for some reason I seem to have very little spare time!, i have always aspired to do as little as possible and up until now i have been very busy and sucessful at it! hahahahah I have tried my hand at a few things, some professionally mostly done very unprofessionally, enjoyed it all, master of none. Love medicine, and still love to read and learn.†

My "migraines" are easy breezy, really, compared to his kind - frequently I get the visual disturbances, but rarely pain, so it's a non-event really - his can get bad, sometimes those 2, 3 day things of wasted down time, until he gets control/rid of it. The first one I ever had was strong tho and scary, lost my balance entirely, double vision so bad I did not know which way was up/true horizon, fell over and could not stand up, mind you it did not last long at all - but hey, YUCK! Glad you tried meds and rest, that was the thing to do. That's a good sign then, an omen, that you found the headache part of it ended up being fairly mild - I bet this IS just a one off, or maybe a sinus influenced thing as you suspect - temporary in nature. If it worries you, don't ignore it, then you should go to the doc, but I think (maybe) you have been pushing yourself just a tiny bit too much with all this working, I know, I know, you felt you could and did and did so carefully, but maybe you did/do need just a little bit more downtime, rest, recoup, relaxing, regenerating time. Consider it still. Maybe that's your bod talking to you saying, "yep, more rest lady, I'm gittin better, on my own timeline, just be patient and treat me even better".

Take your BP for a while (like you did before) just to make sure everything is remaining good on that front. Energy, feeling bagged was a big thing for me, before, during and after treatment - that was the longest thing to resolve. Hang in there and rest, when you feel a wee bit better maaaaybe don't go back to work if you don't have to?, try just booking off for a while and enjoy working on some walks, activities you enjoy, classes of interest, mild exercise programs, stress-free things, good for you/ healthy/ or funner things, which have no big expectations and demands. Possible? Just a thought.†winksmile†C.



-- Edited by Canuck on Sunday 15th of July 2018 03:53:56 AM

__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

thanks canuck, i appreciate your post. i got lucky, even the headache was mild and store bought antiinflamatory worked ok.. advil, took one fourth a pill and it cut it back. as soon as i felt safe enough to see i wasn't having something else i took one half and slept well enough.†

i do hope it's a one time thing too. i do feel tired, drained and kind of sick... so i just stayed in bed today except to eat.

those meds make me feel drained too so hope that's part of it all.

yea, somewhere along the line i learned to think things thru and be more logical than panic too fast........ but i sure was scared

so sorry to hear you and your Mr suffer from these too often.†

i do hope i wake up tomorrow without the fuzzy brain

have a wonderful day, i'm thankful to be at home relaxing and not trying to tough it out a work.

what kind of work do you do?



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

Hey 5!,

Well, that was weird ... about you getting your first and only migraine - I'll say! (understatement) that it must have been (felt) alarming as it came on -† you are a good figurer, or guesser, I suppose that is what i would have ended up guessing too (in the end) migraine perhaps brought on or contributed to by ... some stessors such as ... my, just about anything! But, if i had never had a migraine before, I'm tellin ya, it would have taken me a lot longer (than it did you) to put it all together to come up with a good guess as to what THAT was all about - you did well, to get things thought out and sussed so quickly, a little less mystery, a perhaps leaning to a correct self-diagnosis? ... (long after my first one) I got diagnosed as having migraines without the pain part (lucky eh?!) I just got all the other stuff, aura, visual disturbances/blind spots/growing prisms obscuring field of vision, dizzyness/loss of balance/vertigo. (At least that's what we guess it is that I am doing!) Nowadays, I sometimes do get a headache following the prodromal stuff. My first was quite strong and shocking and profound, and I'll tell you (same as you said) I wouldn't wish for another one like that first one, but all of mine since then I think have been mild if there was anyway to compare to another person's migraine. Just feel very lucky i generally get NO headache with it! My partner gets them bad, his are dif, same prodromal but add nausea, flu-like symptoms, body aches and pains, so ... he always gets optimistically fooled into thinking "maybe" it's NOT a migraine ... (hopeful-like) and then he waits too long to take his meds and often has a longer, harder time to resolve his full out/full blown/well-developed migraine. Sigh. He doesn't get them as often now, as he did in the past tho. The fright of your first migraine you can actually, eventually, become used to (if they persist), once you have recognized what these symptoms might be heralding, and learn how to try to deal with them, they become not so shocking and surprizing - albeit painful, inconvenient and disappointing! For some they are very debilitating, but whether mild or severe we can all learn to deal with them as best we can.

Everybodys' treatment(s) for migraine may be QUITE different - for me, mostly, I do absolutely nothing†(really) - but I will always drink more water if I feel a headache (of any kind) coming on. I might take an OTC tylenol at best, but on occasion, if and when necessary, I will take a stronger scripted prostaglandin-type anti-inflammatory/analgesic drug that we have always had a script for and keep in the house, that just happens to work well for everything from menstrual type cramping pains, to even quite severe post-surgical dental pain, and/or happens to work well for fairly severe migraine pain too (we have found)!†

Docs have tried many dif. remedies for my partner over the decades, he has now refined it down to mostly the scripted prostaglandin-type anti-inflammatory/analgesic drugs which he takes in tandem with another anti-emetic/anti-spasmotic type scripted drug, together they potentiate one another and work fairly well, especially if he takes them early enough to help thwart a fullblown migraine.

I hope this migraine was just a one off for you - maybe you are right about sinuses, and perhaps other influences/contributory factors, and, it IS early days in getting over your HCV cure, things may take time to sort and settle as you become more and more the new and better HCV-less you!†smilewink†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

it's been 14 days since the last pill [well, 15 by now].

i'm happy to report that i'm actually feeling like myself again... nothing weird happening in my bod or mind now.

it took about the full 2 weeks to get here, i guess the half life is 11-14days, and that makes sense why i still had some weird and new sides.

i still have some energy lack that i'm sure will pick up as the days go by.

God bless the daa's. wow. , and ppl who found them.

and the ppl here on the forum that make it feel like the good thing that it is to get treatment..... i feel so blessed that i found this forum†

5



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

thanks canuck, that is a more peaceful explanation; funny they just off hand call it tumor marker round here.hahahaha.

AFP does sound more benign†biggrin

i guess i could never remember afp.... but i will. afp,afp,afp



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

Hey 5,

We hve been talking about AFP's here and here on the site lately ...†

An AFP?? - is a "tumour†marker"!?? ewww, now†THAT just sounds waaay too scary (and maybe too simple an explanation) - I never call an AFP a "tumour marker" (or at least I do not refer to an AFP,†SOLELY†as a tumour marker), because it is NOT (just) that!, it is merely a test, a "rough" guide, a possibly†very helpful one†(when combined with other test results and symptoms), an AFP†can be†a marker of a disease process/disease involvement, an indicator of something awry, an AFP is looked at and made note of, for†other reasons and in other disease states, other than just big ole scary liver cancer!

People can have an temporarily increased AFP (a small blip, or, sometimes marked) simply in response to having hepatitis, and†never†have cancer! I used to think that, that an over-limit AFP meant, .... eww... elevated, then e-gads, i could have cancer!! It is NOT accurate enough to base anything on an AFP†alone†- just remember, some people have liver tumours/lesions/cancer and their AFP was normal or near normal, the next person had NO cancerous liver tissues, ever, and yet their AFP blipped upward†while†they had chronic hep. AFP's are a good a useful tool, when combined with other tests, and repeated over time. It's always a good basic test to have (in my book).†

Lamassu too has twigged onto the careful usefulness in having AFP's done, but still, an elevated result may not necessairyly spell scary-dom. Jes sayin.winksmile†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

thanks tig, that does make sense to me



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

Hello 5,

I thought Iíd provide the information you asked about in Ziggyís thread, here. The A2M is primarily produced in the liver and is an active part in immune function, protease inhibition, and clotting, among others. They even diagnose Alzheimerís or tendency to it in some because a continued deficiency of it may lead to formation of the plaques responsible for it. It can tell of kidney dysfunction, pancreatitis, liver disease, clotting disorders, and a host of other stuff. Itís quite busy! Just know, itís one of dozens of serum components that all combine to tell the bigger story. We have an amazing system!

Alpha-2 Macroglobulin is a serine proteases inhibitor, which inhibits coagulation by inactivating thrombin and Kallikrein, it inhibits fibrinolysis by inactivating plasmin and involved in transport. Alpha-2-Macroglobulin is a large plasma protein, which is produced by the liver, itís composed of 4 identical subunits bound together by -S-S- bonds. A2M is able to inactivate many kinds of proteinases (including serine-, cysteine-, aspartic- and metalloproteinases). A2M has a 35 amino acid "bait" region in its structure. Proteinases bind and cleave the ďbaitĒ region become bound to A2M. Macrophage receptors recognize the proteinase-A2M complex and clear it from the system. A2M binds to and removes MMP-2 and MMP-9 (active forms of the gelatinase) from the circulation using scavenger receptors on the phagocytes. The levels of Alpha-2-macroglobulin are increased in nephrotic syndrome which is a condition where the kidneys start to leak out some of the smaller blood proteins. Due to its large size, A2-macroglobulin is retained in the bloodstream. Increased production of all proteins causes A2-macroglobulin concentration to increase. Chronic renal failure might lead to amyloid by alpha-2-macroglobulin. A2M is raised in cirrhosis, pregnancy and diabetes.



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hey C, casino's are all flashy and lookin fun that's for sure, but the smelly smoke and losing money$$$$$$$$$$$$ are not as fun.[ we have table fans so i love the bosses for bringing them]

and def they have changed thru the times to attract more ppl.

i still have fun where i work, but don't go to any besides work



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hi C, in a way i was expecting to be tested for more VL and liver panel; hubs was but he did 12 weeks not 8 like me.

so maybe they figure since i only did 8 it was ok to wait.... either way is ok with me... and as far as medical teams go they have some lose ends over there. hahahaha blankstare; but they got me the harvoni so the rest is just waiting to know the final score and trusting it remains und and in healing mode now.



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

5,†

HA! Asking Tig about his coffee consumption .... well .... (I have found most addicts, whatever it may be, will tell you the conversation matter is "not on the table" for discussion! heehee), but, I have it on good record, tween you and me, that you may be on to sumpin! Some people near-mainline the stuff, I have heard of others who have even wasted a perfectly good cuppa via enemas and such, of all things! (Let's not go there BTW), but Tig? ... ya I do wonder about his (and Ob's) double, quadruple blotto/blottos. hee hee C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Guru

Status: Offline
Posts: 2626
Date:
Permalink  
 

Hey 5,

Going back over some of the posts here, I am not sure if you were expecting a EOT VL , at the end of your 8 week treatment, or not??

Had your doc clarified for you (ahead of time) what and when your blood tests would occur for you and what they would include??†

He should have, then there are no surprises.

So with your beautiful UND at 4 weeks, and good LFT's, these are the cardinal/important indicators, which will carry you until EOT+12 (SVR12).

BTW - I was never in a Casino until about 10 years ago, I begged my partner to stop so I could look inside - I was shocked, I was expecting to see Frank Sinatra and old fashioned slot machines, like a movie in my mind I guess! I am glad you got a couple extra days off for yourself to celebrate/rest with.

You done it girl! Whew. Nothing now but better health, recovery, regeneration, and a world of knowledge, learning, sharing and all your new friends here!†wink†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

hi tig,

have you checked the obvious suspects for insomnia.

caffeine too late in the day. indigestion. activity or intense tv shows too close to bed. thinking about all the stuff you could be doing or rather be doing instead of sleeping? that last one is a big one for me so i have to remind myself i'm a human being not a human doing.

but the b12 really does help with everything i agree with that.† but i have to take it when i wake up so it doesn't add to insomnia.

if i don't have to work i can usually sleep well enough, unless i have an appointment, that's all i can think aboutcry.

but on work nites the 1mg. valium is a life saver, and i'm no more or less tired than i normally am. i still drink lots of water and have coffee early , and no later than 11pm for a 6am bedtime.

not sleeping is harder on the bod than that little bit of groggy feeling i might have.

so, how about the pot for the preglaucoma? i'm not a fan of the pot but now days they have so many products that don't give you the fuzzy feeling..... but maybe that would help sleep too.

i'm praying sleep will start happening to you easily from now on. 5



-- Edited by 5-1-18 on Wednesday 27th of June 2018 05:33:28 AM

__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.

Tig


Admin

Status: Offline
Posts: 8224
Date:
Permalink  
 

Thanks 5! Iíve been doing some reading since we first spoke and Iím finding a lot of interesting information on the different benefits B12 provides. It looks to actually increase as we age. Iíve got pre glaucoma and my Dad has been plagued with AMD (Macular Degeneration), so Iíve got to be very forward thinking with my eye health in particular. Even though my B levels are adequate, studies show proper supplementation and diet will really make a positive difference. If I could find something to help the insomnia, Iíd be golden!



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



Senior Member

Status: Offline
Posts: 370
Date:
Permalink  
 

tig here is my b12 info

Vitafusion is the one i cut into thirds and quarters for my treatment time. . 2 gummies=1000 mcg/500 apiece

then at wallyworld i found these Spring Valley adult gummy b12 . 2 gummies = 500mcg/250 apiece.

i think it's more tolerable to take low daily doses rather than a shot. it seems to work for my system. and they are fun to eat.

i haven't tried the spring valley one since i have lots of the vitafusion already cut up.†

it really is better on the body to start low and work up, better than how i started high and worked down.

and here is the 100mcg :Solgar - Vitamin B12, 100 mcg, 100 Tablet



__________________

Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=33,00039.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.

1 2 35  >  Last»  | Page of 5  sorted by
 
Quick Reply

Please log in to post quick replies.

Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.