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Hep C Discussion Forum -> General Discussion -> Boceprevir
Post Info TOPIC: Boceprevir
DGiga


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RE: Boceprevir
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Hi Ron, I know I am a little late, but welcome to the forum. It is nice to meet you and I wish you the best of luck with your treatment.     Hugs Dee



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Type 1b with cirrhosis. Started treatment April 9, 2010 for 48 wks. Maintained negative PCR from week 11 during tx but now I am detectable again.
                                                                                                           
Ron Gilbert


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Pj is a new member here and it took her a couple of years to get on a trial. I think it would be worth the wait but Im on tx now. This seems to have been my time for tx so lets hope for the best.

Ron.



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Genotype 1a Diagnosed in 1991. Started tx April 27 2011 for 48 wks. VL before tx  1.6 - 4.6 million. RVR-week 4, UND-week 8 

Vitamin D3 suppliments can increase chances of reaching SVR. See Nutrition section for links.
BJ


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Gidday Ron,

Yes, we did have one member on here start on a trial of boceprevir along with the other two standard drugs.  If my memory serves me right she was doing so well that they stopped her tx about 30 weeks into tx.

They stopped her tx because it had been decided that anyone who went UND at week 4** of tx (like she did) and maintained it could stop at week 24.  It was about week 30 for her when the week 24 results came back. and she'd been UND since about week 2  I think so they let her stop tx.

They did give her the option if she wanted to keep going, but if I remember, she was a young Mum with a couple of kids and was having a pretty rough trot on tx, so she decided to stop.  Last we heard she was going great guns and hasn't looked back.

Sadly, we had another member start the same trial in California, and he didn't do very well at tx at all.  He had a really bad trot with all the meds and had tx stopped at about week 18 or something like that.

Cheers,

Brendan.

**Based on results from the trials they'd done on bocep. over a number of years, all around the world, anyone who went UND at week 4, acheved and maintained SVR.



-- Edited by BJ on Saturday 7th of May 2011 05:46:02 PM

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Geno 1b 72wk tx (Sept '09- Feb '11) Tx sucks, Sx's suck, but no one quits on my watch.   Pre-tx VL - 7.6 Million - Wk 4 - 480,000 - Wk 12 - 19,000....Wks 24, 36, 48 and 72 PCRs were all - negative :-))))Achieved SVR August 2011 

Ron Gilbert


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Hi Randy,

Its nice to hear a kind voice. Its going good. Lets of dizziness but I'm staying active and I'm making myself laugh watching dumb nighttime comedy shows. lol. It seems to help a little. Also a nice glass of milk at night seems to help me sleep. I'm trying to avoid other drugs but do take some IBuprofen a few times a week.

Thank, Ron.



__________________

Genotype 1a Diagnosed in 1991. Started tx April 27 2011 for 48 wks. VL before tx  1.6 - 4.6 million. RVR-week 4, UND-week 8 

Vitamin D3 suppliments can increase chances of reaching SVR. See Nutrition section for links.
Hep Me


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Hey Ron, good to have you aboard. Great to hear you started tx and hope all is going well for you so far.

Take care,
Randy



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"Ah but I was so much older then, I'm younger than that now."  Bob Dylan
Ron Gilbert


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Thanks James, Im 2 weeks away from my 4 week VL test so Im hoping the 3rd drug wont matter (to me) because I wont need it. Its nice to know its out there though in case this dosnt work for me!



__________________

Genotype 1a Diagnosed in 1991. Started tx April 27 2011 for 48 wks. VL before tx  1.6 - 4.6 million. RVR-week 4, UND-week 8 

Vitamin D3 suppliments can increase chances of reaching SVR. See Nutrition section for links.
James10500


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Yes you add it. Another drug is Telaprevir which is added also. SVR rates for geno 1 are about 70%, for 2 about 85%, and it doesn't as well for 3's, and I think 4s are the same as 1s. This from memory so correct me if I'm wrong guys. James

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Diagnosed 4/13/10; Started Tx 8/13/10; SVR 7/27/11
Ron Gilbert


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"Peginterferon (injection) and ribavirin (pill) have been the standard treatment for more than 10 years, which Barr said achieved success only 35 percent to 40 percent of the time and required 48 weeks. Boceprevir is designed to work in combination with those two other drugs. Barr said that Merck's studies showed that among patients who were never treated before, boceprevir was successful more than 60 percent of the time in only 24 weeks."

http://articles.philly.com/2011-04-26/business/29474900_1_hepatitis-c-virus-fda-approval-fda-advisory-committee

According to this they are just adding a third drug to the mix. Has anyone taken it yet??



__________________

Genotype 1a Diagnosed in 1991. Started tx April 27 2011 for 48 wks. VL before tx  1.6 - 4.6 million. RVR-week 4, UND-week 8 

Vitamin D3 suppliments can increase chances of reaching SVR. See Nutrition section for links.
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