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Post Info TOPIC: Risk Factors of Sexual Contact and HCV.


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Risk Factors of Sexual Contact and HCV.
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Sexual contact

 

The risk of sexual transmission of hepatitis C is considered very low. However, this risk increases for sexual activities where there is potential exposure to blood. This includes vaginal sex during menstruation or anal sex with the associated risk of bleeding. Sex toys used during these activities are also potential source of infection.

Oral sex in the absence of blood is considered to be a low risk activity. In addition, the presence of certain sexually transmitted infections may increase the risk. Unprotected sex, even once, with someone who is co-infected with HIV and HCV poses a significant risk. The risk of hepatitis C transmission is much higher in the presence of HIV. Read the results of a 10 year study into sexual transmission below:

Sexual transmission - European study

No Evidence of Sexual Transmission of Hepatitis C among Monogamous Couples: Results of a 10-Year Prospective Study

The risk of sexual transmission of hepatitis C virus (HCV) infection was evaluated among 895 monogamous heterosexual partners of HCV chronically infected individuals in a long-term prospective study, which provided a follow-up period of 8,060 person-years. Seven hundred and seventy-six (86.7%) spouses were followed for 10 yr, corresponding to 7,760 person-years of observation.

One hundred and nineteen (13.3%) spouses (69 whose infected partners cleared the virus following treatment and 50 who ended their relationship or were lost at follow-up) contributed an additional 300 person-years.

All couples denied practicing anal intercourse or sex during menstruation, as well as condom use. The average weekly rate of sexual intercourse was 1.8.

Three HCV infections were observed during follow-up corresponding to an incidence rate of 0.37 per 1,000 person-years. However, the infecting HCV genotype in one spouse (2a) was different from that of the partner (1b), clearly excluding sexual transmission.

The remaining two couples had concordant genotypes, but sequence analysis of the NS5b region of the HCV genome, coupled with phylogenetic analysis showed that the corresponding partners carried different viral isolates, again excluding the possibility of intra-spousal transmission of HCV.

The authors conclude, Our data indicate that the risk of sexual transmission of HCV within heterosexual monogamous couples is extremely low or even null. No general recommendations for condom use seem required for individuals in monogamous partnerships with HCV-infected partners.

Reference
Carmen Vandelli and others. Lack of Evidence of Sexual Transmission of Hepatitis C among Monogamous Couples: Results of a 10-Year Prospective Follow-Up Study. American Journal of Gastroenterology 99(6): 855-859. May 2004.

With thanks to the Hepatitis C Trust.

http://www.hepctrust.org.uk/Hepatitis_C_Info/Risk+Factors/What+are+the+risk+factors/Sexual+contact#.TyfZrS8IacQ.facebook



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