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Post Info TOPIC: Biopsy yesterday for 7977.


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RE: Biopsy yesterday for 7977.
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Man, you got a lot to be happy about. Fine looking folks. Hope you're feeling OK and kicking some virus butt. Virus butt kicking is a popular sport these days.

Alan



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Geno 1A  Started Pegasys/Ribavirin/Incivek Nov. 20, 2011 .  Completed July 28, 2012 (36 weeks). For a treatment history, see:  https://jshare.johnshopkins.edu/xythoswfs/webview/_xy-9921874_1

SVR on January 14, 2013!!



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lol........I wish.......I'm old, those are my kids........lol



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jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 



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Hey, Jim

One dumb question....in the picture, which one are you?

Alan



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Geno 1A  Started Pegasys/Ribavirin/Incivek Nov. 20, 2011 .  Completed July 28, 2012 (36 weeks). For a treatment history, see:  https://jshare.johnshopkins.edu/xythoswfs/webview/_xy-9921874_1

SVR on January 14, 2013!!



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Good luck man we are all rooting for ya!



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Geno 1 A Started Tx 8-3-11, Viral Load  21.2 Million,  4 Week Lead of Soc ,9-1-11 <43 On Soc alone started victrelis 9-3 ,8 week pcr vL und.Week 12 Vl Und, Did Week 24 PCR Results UND @ Week 24!!! 1-11-12,End Of Tx 2-15-2012 !!



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Wow Jim! This is so exciting!! I can't wait to hear about this new tx and am cheering you on! Starting tomorrow?! So cool
Shep

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Diagnosed 1996 genotype 1b VL alot tx starting 12/23/11 Victrelis UND week 8!!! 28 weeks of tx

Completed tx 7/6/12--still UND!!!!



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Hey jim

 

So they took me off all treatment in week 8 after I went from 5000 to one million.  I have tried interferon 4 times and o for 4.  I am also stage 2 level 2 unchanged from ten years ago - I did a study with BMS7000 last year with interferon and ribravitrin - it didin't work...  let me know how yours goes!!!



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 



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Good luck and keep us posted.

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Good Luck and kick viraassss



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1a,incivek- 24 months,und 24 months on 01/2012



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Hey Jim,

WOW Fantastic news mate, as Jill said your a pioneer. I wish you all the very best and as you know everyone here will be in your corner.

Slay the Dragon.

Greg



-- Edited by Greg on Thursday 15th of March 2012 08:52:43 PM

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The mind is like a parachute it works best when it is open. "The Dalai Lama" My blog: http://greghcv.wordpress.com/
Genotype 1a, started tx 1st Feb 2011, for 48 wks. Week 24 PCR 26/07/11 Non-Responder
New TX start date 12th Sept 2016 Harvoni x24 weeks.  VL 7.4 Mil. Week 4 "Undetected"



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Thanks everybody!!!!!!

Tomorrow is what they call Day -1. Bloodwork, ekg, a complete physical and once over.  I start the meds on Friday. I'm excited and ready to go. I will need to do some creative scheduling for work for the next 2 weeks. After that it's only once a week then once every 2 weeks. The weather here has been great this week. I hope it keeps up. 



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jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 



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Jim, I'm so happy you stayed at Stage 2/Level 2 for past years and are now able to do this trial!  Certainly sounds like it was meant to be.  I don't know anything about the newer drugs so very much looking forward to updates from you.  You have a wonderful outlook.

Hugs,

Judy



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Geno 1a; VL 4.7 million in Feb 2012. Started PegIntron & Ribavirin 3-9-12. Added Victrelis 4-6-12. UND since Week 8. Stopped tx Wk 23. UND 4 Wks post-tx. Relapsed 12-weeks-post.

52 y/o F, started Epclusa 11-10-19, F0/F1.  EOT 2-1-2020. UND. All liver function tests normal.



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Jim, that's great news! So happy for you!

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Genotype 1a, non responder to Peg/Riba in 2005. Started triple therapy 1-27-12 with Victrelis.  UNDETECTABLE as of 8wk labs (after 4 weeks of Victrelis) 4-3-12. UND at week 8, 12, 16 & 20 of tx. Completed triple therapy Oct 2012. relapsed 10/2012



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Yes! Great news Jim, so pleased for you!  biggrin  The time you spent on tx will have helped your liver too, it wasn`t all in vain!

Fantastic that your doctor is so supportive, and also your trial doctor, sounds like she`s going to be such a huge help along the way.  You`re a pioneer Jim!

Looking forward to following your progress and hearing all about it, we`ll all be here with you every step of the way!

Good luck!  Jill xx



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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This is so great!  It could not be better unless of course it was happening to me.  Just kidding.

I want to hear everything about this.  Would it be too much to ask that you keep a daily journal noting all things great and small, and then, at the end of each day share every single detail with us?  Just kidding again.  Please do keep us updated though.  

Btw, well done taking such good care of your liver for the past 10 years.  You must have been doing some healthy living. 

Sincerely,

Person of Earth 



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.



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Yeaaaa, awesome news!

And I know what you mean about things happening that were "supposed" to.  I can't explain it, but I sure see it in my life a lot.  I notice you stayed on the forum, even when you had to stop TX, and you mention "the next go round" on your earlier posts.  I guess it just happened sooner than you thought. Wonderful!

Brad



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(Geno 1a, Incivek Triple Tx, 6 month post TX - 9/20/2012 = SVR!!!)



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Cooooool JIm, Please keep us updated, wishing you the bestbiggrin, Iris



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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)

ty


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That is fantastic news Jim!  I am so happy for you.  I agree with the doc you are one of the heros in this battle!  Take care tysmile



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Genotype 2 - 24 week Tx - Start 10-8-2010 - 4 week PCR test UND, 12 week PCR test UND, 24 week PCR UND,  SVR Oct. 11 



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I'm in!!!!!!!!   Stage 2 Level 2. Same a s 10 Years ago.  Amazing to me. Brad you were right!!!!!!!

So many things have happened in the last 10 days to allow this to happen I can't help but believe I am supposed to be on this trial.  No matter what happens in the end I am very grateful to all my Dr.'s, my family, and my friends who have given me way more than I could ever give back to them.

I ran into my Gastro Dr. in the hospital right after I got the results and he said it was good that I was doing it because it would help people in the future who are battling this disease.  It gave me goosebumps.......he's a great guy and has no ego.  He supports me 100% and encourages me every time I see him.

My Dr for the trial is also an amazing, giving person who is the sole reason I'm able to try this tx. I would not be given this oppurtunity without her.

And not a day goes by without me thinking of all the good people on here who got me started back in September and who are always encouraging and supporting everybody on tx.  You guys are the best of the best.

Thank you all.  Round 2 is about to begin.............



-- Edited by JIme on Wednesday 14th of March 2012 12:26:05 AM

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jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 



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Hey Jim
Hope all goes well--let us know!

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Diagnosed 1996 genotype 1b VL alot tx starting 12/23/11 Victrelis UND week 8!!! 28 weeks of tx

Completed tx 7/6/12--still UND!!!!



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Thanks everybody I will keep you posted.

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jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 



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Hi JIme, wishing you all the best with your biopsy results, so you can get on that trial smile

Keep us updated!

Love Steff xx



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Geno 3a. 24 wks tx 20/10/05 - 06/04/06. Achieved SVR.



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This is very good news, Jim.  confuse  I am hoping everything goes really well for you.



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.



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All the best of luck Jim, keep us posted!  thumbsup.gif

Jill xx



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Hi JIme,

You were 2/2 a few years ago, so I'm betting your in!

Good luck!

Brad



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(Geno 1a, Incivek Triple Tx, 6 month post TX - 9/20/2012 = SVR!!!)



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Good luck, got my fingers crossed for ya!


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Genotype 1a, non responder to Peg/Riba in 2005. Started triple therapy 1-27-12 with Victrelis.  UNDETECTABLE as of 8wk labs (after 4 weeks of Victrelis) 4-3-12. UND at week 8, 12, 16 & 20 of tx. Completed triple therapy Oct 2012. relapsed 10/2012



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I had a biopsy yesterday in hopes of being Stage 3 or less so I can go on a trial for 7977 and the BMS drug ( forgot # ) and maybe riba.  Several people are starting it or have started this week.  If I am above stage 3 I am not elligible for this trial.  I will look for something else then.

I was on Triple Tx w/telaprivir for 8 wks and had to stop due to rising VL.

It went from 11.2m to 430 by week 4, then at week 8 it was 20,000. Dr said it mutated and got around the medicine, smart virus heh?

I am GT 1a, null responder and will find out next week what the dilly-o is.

Hope everyone is doing well.



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jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 

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