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Hep C Discussion Forum -> New Members Area -> Is anybody post transplant and on triple therapy?
Post Info TOPIC: Is anybody post transplant and on triple therapy?
mallani


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RE: Is anybody post transplant and on triple therapy?
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Hi Will, I haven't been fishing for 42 weeks, which is the period I've been on triple Rx! Can't wait to get back out on my boat.

Thanks for the info about the use of antiproteases post transplant. I hadn't seen anything published. It makes sense to try to get the VL down and hopefully the newer drugs being trialled can be used post transplant. I presume you're on Ciclosporin, and wonder how that will interact with the PI's. Good luck and please keep us informed of your progress. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Will


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Found out I had C in 1997. Transplant in 2007

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mallani


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Hi Iris and Will, the protease inhibitors are not approved for post-transplant HCV. All patients with circulating Hep C virus become reinfected after transplant. Treatment with Peg and Riba can be used, but side effects are often severe.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Will


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Malcomb you are right triple is not approved yet, however has been used at several medical institutions for about a year, I will be Guinea Pig starting in about one month, Have to change from Prograf to Cyclospoem. By the way Malcomb, like the fish, are you still fishing?

-- Edited by Will on Friday 4th of January 2013 12:54:50 PM

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Iris Dragonfly


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Hi  Will, gee you have had a tuff time of it, there is lots of info here and many new treatments are on the way. Malcolm...will he be eligible to do treatment post transplant? I wish you all the best Will, Blessings...Iris



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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)
JoAnneh


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So u didn't beat disease before transplant!
Wow, u have been thru the ringer.
How long have u had Hep C?
Have you had a liver biopsy?
I am 53 w cirrhosis, hoping for SVR!
Hope we all find a cure:)

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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!
Will


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i've had interferon treatment and peg with ribiviron pre transplant. Now C is sneaking up on me again 5 years post transplant.

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