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Post Info TOPIC: Question about new tx


Guru

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RE: Question about new tx
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Iris Dragonfly wrote:
heck...I can't seem to figure out how to make it so you just click on the..confuse


Hi Iris, if you want to know how to make you links `clickable`, have a read of the reply I gave to Neil a while back...

http://hepcfriends.activeboard.com/t52321823/creating-hyperlink/

Hope that helps! smile



__________________

Jill

(69 yo, lives in UK)

Was Gen 3a,

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT,

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.



Guru

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Hi there King, yes Gilead Sciences are filing for regulatory approval for Sofosbuvir (previously called GS - 7977) this year. Based on the results of their phase 3 clinical trials it looks like it will an all-oral treatment with ribavirin for genotypes 2 and 3, but for genotype 1`s they will need to add ribavirin and peg interferon to make it more effective until they can get approval for their new drug GS - 5885, an NS5A inhibitor.

If you have a browse through the Clinical Trials section you`ll see that we post regular updates on new drugs and also have some `sticky` threads for members who are on various clinical trials, including ones from Abbott who also have some promising looking new drugs in the pipeline

The future`s looking good for much easier and more effective treatment regimes! ~ Jill



__________________

Jill

(69 yo, lives in UK)

Was Gen 3a,

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT,

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.



Senior Member

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Forgot to mention, that the course will take 12 weeks or maybe even less.



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58 yo male, HCV since 1981. Gen 1B (IL28B, CT). Diagnosed1999, VLbefore tx 100'000.Biopsy A2, F3fibrosis. Naive, SOT (with Incivek)Oct 26, 2012. UND @ week 4, 12, 18, 24, UND 12 and 24 weeks post-RX



Senior Member

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Yes, its about Sofobuvir, which might be available towards the end of the year. Interferon free treatment, oral meds ony, combo with another Gilead drug

(dont remember its name/number). My liver doctor recommends his GT 1 non-cirrhotic patients to wait.



__________________

58 yo male, HCV since 1981. Gen 1B (IL28B, CT). Diagnosed1999, VLbefore tx 100'000.Biopsy A2, F3fibrosis. Naive, SOT (with Incivek)Oct 26, 2012. UND @ week 4, 12, 18, 24, UND 12 and 24 weeks post-RX



Guru

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Hi King

I'm hearing the same and I won't do Inf / riba again. i just finished my 3rd treatment since 2009 I felt compelled to get treated cause I have some symptoms that can be really uncomfortable and didn't really do enough research. I don't seem to last UND with interferon and riba alone. I did a trial the was stopped by the FDA, being UND at the time tried to finish with Inf/ riba but didn't hold out. 3rd time 12 weeks Inciveck which did bring me UND but when just inf & riba it broke through again My theory and its just what I think (I have nothing to back it up.) my virus or my body don't hold with just inf So I'm waiting on the 2014 new drugs ( I hope ) I'll stick with the virus till it does come out. I hope you do well whatever. There are a lot of people clearing and some failure and it's a tough ride. Good luck

BillS

And yes thats the one Dragonfly or a combo with that 7977



-- Edited by Bills on Sunday 3rd of March 2013 04:10:00 AM

__________________

Bills

Harvoni started 12-12-14 for 24 wks PrevTX Geno 1 stage 3 cirrhosis - non resp Int/ ribv. Started Trial in Aug 2011 -July 2012 into Incivek relapsed Feb 2013 Had 72 weeks on interferon & Riba.



Guru

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Hi...it's me...I'm hoping the one that cured Jim (forum member) will be available to all very soon. I have recently been referred to USC ....I wonder what they'll offer. Looking for that one....(I would also like to add, it's your choice...not the Dr...just my.twocents.gif)

Jim had quite a journey, hope he doesn't mind...here's the thread

http://hepcfriends.activeboard.com/t48295757/7977-journal/

heck...I can't seem to figure out how to make it so you just click on the..confuseok...find it this way, go to the clinical trials...then look for 7977 journal by... JIme

I'm feeling really computer lame tonite....evileye

Good luck ...and have a great weekend smile Iris



-- Edited by Iris Dragonfly on Sunday 3rd of March 2013 04:04:43 AM



-- Edited by Iris Dragonfly on Sunday 3rd of March 2013 04:13:53 AM

__________________

in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment nave....UNTIL 7-01-18 !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)



Senior Member

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I also waited until my doctors told me a couldn't put off treatment any longer . I would leave it up to your Dr. I waited over 27 yrs. just because the first Hep. Dr. Told me the longer i wait the better the Rx.

Yes there are better Rx on the horizon. I wish I didn't have to take the Teleparvar. But I'm also non detectable. I'm going for my 24 wk. Next week.



__________________

25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24



Veteran Member

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Hello, King here. Thanks all of you for your welcomes. very much appreciated. I have a question. Ive read online about some new tx coming in 2014 and that the tx is only like 16 weeks or so, it doesn't make you sick and has like a 85% success. If this is true should I try and habg in there until 2014 and try this new tx. I'm only asking opinions, I know its going to be up to the Doc. I just want to have as much info as possible when I go and see Doc in a month. All opinions welcome.



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