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Post Info TOPIC: Abbott Sapphire phase 3


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RE: Abbott Sapphire phase 3
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Great news Valerie, SVR is always a good news day.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Hi Valerie, good to hear from you..and congratulations on SVR24!  Really pleased for you, thanks for sharing such wonderful news! 

Enjoy being Hep C free!  smile



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Hi Valeri

That is great news that you are free of this. I took a quick look and we are born the same year from the same country and I am pretty sure we took the same drugs so it would be nice to get the same result as well.. lol Take care Terry

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Geno Type 1a stage 4 cirrhosis EOT 52 weeks SVR !!



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Hello Valerie

Congrats on your six months SVR results, enjoy the rest of your life.

matt



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



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Valerie,
Congrats on SVR!!!, am also a "newby" here, just thankful every one is good enough to let me hang around and learn the good, bad, and the ugly of the disease, treatment and recovery. So far I am seeing a lot of good, lots of SVR, and lots of good people. Best wishes on your continuing recovery. Its gonna get bettter every day!!

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John


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Hi Valerie,

Congrats on your SVR24!  Abbott have been fairly quiet, but obviously have a good combo. Enjoy a happy HepC-free life. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Congratulations!!!

Looks like you are officially SVR. 100% SVR at your trial site sounds really good to me. Gilead is going publicity wild, but there are other meds (companies) that are doing really great in trials. I wonder when Abbott goes for FDA approval as yours was a Phase 3 study. Merck, my study, is still in Phase 2. So glad you did not get placebo.

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Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR

Tig


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That's fantastic news! Congratulations and happier days ahead!! Good luck! smile



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Tig

65 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 8+ years!

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Hi All

Just an update from my 6 month post treatment.  Results were undetectable and I feel good.  My study nurse mentioned, that 6 of us were in the trial and were lucky enough to all get the drugs and now 6 months post treatment and everyone doing good.  Good luck to all, and I hope this is soon available to all.



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Thank you Matt, I hope you are right about the anemia.  I am so tired, ha and now only my 2nd week almost finished, and I am just feeling so darn crabby.  I really have to bite my tongue.  Lucky I have only had a few headaches.  I have no idea why I am crabby, work is the same, everything is the same. I have no reason to be crabby and if I got the real drugs, then I should be happy, which I would be.  My chest hurts when I walk at lunch, and I told my friend not to walk so fast.  At least by evening, it is better and I can still do the treadmill... with effort. At least Easter is coming and some days off.  good luck to you too



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Hi and welcome, Valerie, wishing you the best of luck this time round.  s We`re always pleased to hear from people on clinical trials and will be very interested in following your progress.  As you`ve already seen, we have other trial members here you`ll be able to compare notes with.  

I`m moving this thread to the `Clinical Trials` section and making it a `sticky`, which means that it stays at the top of the section along with the other trial threads.   ~ Jill



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Valerie 

I have been on these Meds for almost six week and if your body is like mind,  it will adjust and get used to them with less anemia and less high Billirubin levels.

I suspect that this treatment is whole lot less problems than the current SOC, so be very thankful as I am that you made the cut. I was very stressed to be selected, thinking I would not qualify.

What was strange for me neither the Doctor nor my nurse told me what to expect and how to eat or drink or any tips on how to deal with issues.  Learned a lot more on my own and from the other members of our forum. Most of us on the Abbott Labs Meds agree that it is important to keep hydrated especially during the first two weeks.

Just my opinion , no facts

Matt.  (on the Turquoise II open label version trial study)



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



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Thank you all for your responses. I just started my 2nd week. Unfortunately, I will not know for 12 weeks, as there are 2 arms, but either way I will get the real drugs, I just hope sooner. The nurse told me this morning, that we can guess but that is all. She does not get results for the liver enzymes, or bilirubin. However, I know one drug can raise it and make you yellow, I am ok with that. I know the Riba can make you anemic, etc and I think it is affecting me. I can barely get out of bed, I mentioned that to the nurse and she said they will tell her that. I wanted to see a dr today, because I wanted to ask if Alertec is ok Hopefully a dr is around next week. This is my 2nd trial, the first I got booted from because interferon, caused my white blood cells to go less than 0, so I needed neupogen weekly and after 24 weeks, i was less than 0 and could/should have rolled over into the trial with the real drugs, but they didnt want me having neupogen for another 24 weeks, so i got booted. I was choked, but oh well, at least i kept my hair lol. The liver drs at the clinic all said I was their first patient using that. I think they should have pursued it. So, they thought this Abbott study was must better for me. I will check and see if I can find what the other people say about this study. thank you all

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good luck with clinical trial!

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GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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Welcome Valerie, good luck on your trial.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Hello & Welcome Valerie

The forum can really help you with your journey,  with many members having great insights into the ups and downs of the treatment. So don't be afraid to ask 

I am on one Abbott Labs Trial programs called Turqouise II. The difference is our study is for cirrhotics and is a open label study, which means that we know the drugs are real and get real time results on our progress. You can read about our journeys on our threads

Hope all go's well

Matt



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



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Hi Valerie,

Welcome to the Forum. We have 3 Forum Members doing Abbott Trials. If you check the Section marked Clinical Trials, you will see the names and details. From memory they are 'Matt Chris', 'Luv2ryde' and 'Balagan'. They seem to be doing well, and will probably answer your post. Good luck.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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ok i try here, i am new, and genotype 1b,  started the Abbott sapphire phase 3 5 days ago,  wondering when side effects kick in lol that is about it

 



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