Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> Clinical Trial Participants -> Started Sapphire Phase III Today
Post Info TOPIC: Started Sapphire Phase III Today
Greendream


Member

Status: Offline
Posts: 11
Date:
RE: Started Sapphire Phase III Today
Permalink  
 

Good Morning

Thanks all  for your advice and well wishes smile.

Wish i could have a daily nap Matt, but i can't with the responsibility of being a single parent with 2 children aged 8 and 10. It's the school hols half term week here and i'm also off college so i'm gonna be kind to myself and go with the flow. No alarms for a week yay - nothing beats waking up naturally. I love my sleep, and fortunately i've suffered no sleeplessness on the 'pills'.

I have my Week 4 appt on thurs to stock up on more pills, hope i can get some kind of results/indication of activity of something happening (alt, ast).

Lisa, i feel so lucky compared to many on this site to not have any damage to the liver after 16 years, i must say though - i am sure it has had an impact on the clarity of my mind. Total brain fog episodes. It would be a gift to get my mind back 100% (not to mention being totally free of this lurking dragon).

I wanted to add something about another possible effect of these pills - from my personal experience the last few weeks - i have to limit my chocolate/sugary intake! I love sweets and go a bit mad on them. I'm talking about scoffing bars of chocolate and packets of jelly beans. They ain't agreeing with my health! I get heart palpy and i think it makes the dizzy spells worse. I smoke too unfortunately - but have cut right down. Not in the head space to pack em in completely. Down to about 7 roll ups a day.

I would like to wish you a great sunday, the sun is beaming today smile



__________________

40 yr old female, Genotype 1a. Started Abbott Sapphire Phase III trial on 30 April '13. Hep C diagnosed in '97.

 
Loopy Lisa


Guru

Status: Offline
Posts: 895
Date:
Permalink  
 

Good on you for going with this trial. I see you have had the virus a very long time, so let's hope you get the SVR as a gift at the end. Good luck!



__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 
Matt Chris


Guru

Status: Offline
Posts: 1782
Date:
Permalink  
 

Hey Greendream

Sounds like your body is adapting to the Meds. It was normal for me to be sleepy everyday around 6:00 PM on the same Meds.

I think the best way to handle it is to make a plan for a daily nap or two, because your body is telling you to rest to regain strength.

My whole 12 weeks on the Abbott trial was like that, so go with the flow and let you body take a break. Before you know it you will be done

Other thing I learned, have a EOT (end of treatment) strategy.

Matt   



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
Cinnamon Girl


Guru

Status: Offline
Posts: 5629
Date:
Permalink  
 

Thanks for the update, Susan.  You`re bound to be thinking about side effects, anyone would be in your situation.  Good that your stomach upset symptoms and dizziness settled down quickly.  Take it easy...

...and let`s hope we get some sunshine soon!  

 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Greendream


Member

Status: Offline
Posts: 11
Date:
Sapphire Phase III Participant UK
Permalink  
 

That's me now on my 4th week of pills. I found the 1st week a breeze - then towards the end of the 2nd week, out the blue i had a dizzy turn followed by throwing up and diarrea (scuse the spelling).  Since then it's been on and off light dizziness and headaches (which i take paracetamol for) but no more throwing up. I'm not that concerned and i'm hoping it's just side effects from the pills. (I'd be a robot if it didn't cross my mind!)

Wish the weather wasn't so pants here, i need my sunshine!!!

 



-- Edited by Greendream on Thursday 23rd of May 2013 11:38:10 AM

__________________

40 yr old female, Genotype 1a. Started Abbott Sapphire Phase III trial on 30 April '13. Hep C diagnosed in '97.

 
Greendream


Member

Status: Offline
Posts: 11
Date:
RE: Started Sapphire Phase III Today
Permalink  
 

8 1/2 Stone is 54KG.

You're right Luv, i'm not going to ponder anymore. There's no point. Just had the 2nd dose about an hour ago and feel really chilled out. I'm going to get treated and that's all that matters. I hope the rest of your time on the real deal flies in with little sickness.



__________________

40 yr old female, Genotype 1a. Started Abbott Sapphire Phase III trial on 30 April '13. Hep C diagnosed in '97.

 
LUV2RYDE


Senior Member

Status: Offline
Posts: 161
Date:
Permalink  
 

Greendream how much is 8 1/2 stone???? Don't ponder too much on "am I taking the placebo" just remember the outcome ......UND and SVR!!!!! I totally understand where your coming from with the double blinded study. On May 3rd I will be at my fourth week and am looking forward to the next two months going by quickly and hopefully not being sick. Very happy for you!



__________________

Geno type 1A Started Abbott clinical trial mid Jan 2013. :-)

Viral load when I started this trial 4.75million  Went 12wks on placebo and started real meds on 4/5/13 after 1wk  on real meds 25 after UND @3wks,6wks.w00t: Done trial 6/27/13 and still UND.

 
Greendream


Member

Status: Offline
Posts: 11
Date:
Permalink  
 

Day 1 of Sapphire phase III trial, had my first dose of 'meds'. After bloodwork, ECG, weight and Questionaires, the nurse explained the dosage routine and side effects (which i was mostly aware of). I felt at ease there, they're a friendly lot and my nurse was great in answering any questions i had. Because i'm only 8 and a half stone, i got 1000mg of Riba. I had a cuppa and swallowed them there with the nurse, she asked me how i was feeling, and i felt fine. So, no adverse side effects. It's now about 2 hours since the drugs and i really don't feel any different - can't help but thinking that i would KNOW if anything alien was in my system..so i'm already thinking it's placebo haha. Jeez, i'm not gonna ponder this too much (i hope). Decided to take 2 in the morning and 3 at night, because i sleep so well normally - but if i end up with sleepless nights then i'll know something's up. I suppose it's too early to say after just 1 dose.... i got bit of a metallic taste in my mouth, but that could be anything...

I found out something which struck me as weird. My viral load last october was only 84,000 (that is low!) but the year before it was 380,000 (why? i can't imagine what aggravated it). The nurse said it could be up again, but she can't say as it's blinded results now. 

On with ze day!



__________________

40 yr old female, Genotype 1a. Started Abbott Sapphire Phase III trial on 30 April '13. Hep C diagnosed in '97.

 
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> Clinical Trial Participants -> Started Sapphire Phase III Today
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.