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Post Info TOPIC: The new drug Sofosbuvir


Guru

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RE: The new drug Sofosbuvir
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All being well I will be on Sofosbuvir in march. Cure rates for GT3 are only good with 24 weeks. On the new generation DDAs GT3 is now the hardest to treat. 

I will still have to do 6 months, but at least i dodge the interferon bullet. I think can manage that OK, well I hope anyway!

In the Netherlands they cannot refuse us drugs even with high cost if it is of public benefit. The insurance company wont like it but they can't refuse. :D



__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



Senior Member

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I am also 1a and waiting on sofosbuvir. I have an appointment in late January to hopefully get me started on it. 12 to 16 weeks surely beats the alternative 24 to 48...as well as less side effects.

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Type 1a. Had HCV my entire life via blood transfusion. Did peg & riba in 2000, relapsed. Did triple tx with sovaldi in early 2014 & I am now undetected 



Senior Member

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Hi Lonewolf,

Check out the clinical trial thread here and the on treatment thread.  Lots and lots of great information there. 

SuziQ



__________________

Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR



Member

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   My Dr. at the VA wants me to start the latest and whats supposed to be the most effective drug Sofosbuvir shortly after its approved by the FDA. It was endorsed by all 15 members on Oct. 23, 2013 and is all but certain to be approved in early Dec. I am type 1a so I will be taking it in combination with Ribavirin and the dreaded Interferon. Very expensive I hear but that won't be an issue for me. And the treatment will be from 12 to 16 weeks instead of the longer treatment usually required for 1a. There is a lot of in-fighting among the various drug companies concerning patents and stuff since its a goldmine for them but he said I should be able to start it in Jan. of 2014. The VA has first dibs since so many vets are infected with Hep C. Also, there are other drugs sure to be approved very soon which won't include Interferon even for type 1a. I don't profess to be an expert on Hep C, I am just going by what the Infectious Disease specialist at the VA tells me. He tells me these are very exciting times as far as Hep C treatment and that Interferon will soon be just a bad memory. Of course, the cost of these new drugs will be tremendous. So its a matter of money and/or insurance coverage for many people. Just wondering if anyone else is considering these new drugs or taking them once they are approved. I'm told the cure rates could reach almost 100%, especially for Genotypes 2 and 3. We'll see.



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55 yo male-Genotype 1A  Started treatment 3-5-15 Viekira Pak+Ribavirin 12 weeks. Less than stage 1 fibrosis.  Previously treatment naïve. VL- SOT-21.8 million/ml  Log 10IU/ml-7.34, VL-4wks-UND, VL-7wks-UND

Greg

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