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Post Info TOPIC: The Amazing new off Label Combo Olysio & Sovaldi


Guru

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RE: The Amazing new off Label Combo Olysio & Sovaldi
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Absolutely, Matt, and I think we`ve all been very surprised to see how many new members are having this drug combo approved.

Unfortunately, it looks like some people are now running into problems with their insurance companies, so it seems like it`s still early days as far as getting it fully accepted as a treatment option is concerned.  It seems a shame that the Cosmos trials only went to Phase 2 and that Phase 3 trials weren`t done, which would have provided much stronger data for insurance purposes.

Wishing everyone on the Olysio/ Sovaldi combo all the best of luck! 

 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



Guru

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Its quite amazing and great news that this combo (Olysio & Sovaldi) is being prescribed and then approved by insurance companies since its off label from FDA. I guess that the medical machine has more power and influence with the insurance that we thought.

With all the patients being prescribed this combo in first half of 2014 its like having another phase IV trial but with real world variables and a lot more individuals with advanced liver disease being in the mix we should have no doubt about whether it will be effective or not.

This will really help indicate to us how well this combo will work and set a standard for an all oral treatments. It could also raise the price tag for insurance companies to moderate the HCV market, they might be more willing to pay out if it sustains a high cure rate.

matt



-- Edited by Matt Chris on Friday 21st of February 2014 09:00:57 PM

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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 

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