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Hep C Discussion Forum -> General Discussion -> HCV and teeth
Post Info TOPIC: HCV and teeth
Huey


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RE: HCV and teeth
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mallani wrote:

Hi all,

Every 6 months I do a post about the effect of HCV on teeth. Chronic HepC causes decreased, acidic saliva. This promotes tooth decay. For those patients who are put on Interferon, the problem gets worse. Interferon has a direct effect on tooth enamel, and further reduces saliva production.  Add the decreased neutrophils, and dental decay is a real problem. Back in the 1990's, this effect of Interferon was not mentioned. I lost 3 significant teeth from that experience. During my last 48 weeks of treatment, I still ended up losing 2 more teeth. This was despite a dental check prior to treatment, and 3 monthly checks during treatment ( although I missed the last one, as I was too ill). This will become less of a problem as Interferon disappears, and treatment times get shorter. However, get your teeth checked before treatment, use a mouth wash, and brush your teeth at least twice a day. I still have a dry mouth, so the damage to my salivary glands is probably permanent.

I have just had my final titanium screw inserted for another dental implant. I've researched implant types and cost and I'll do a post in 'Off Topic'.  Cheers.

 Does your teeth get sensitive to hot and cold too?



__________________

  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
jimbob


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Several years prior to tx, I had 4-5 teeth chip too Duane. I'm sure they're weakened by having had the virus for so long.

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jimbob: 64 y/o, GT 1A, F1-F2, diagnosed 1996. Since 1970. SOT 3.5 mil VL on 3/10/14 with Sov/Rib/Peg for 12 weeks. Tx naive. UND @ week 4,8,12. EOT 6/2/14.
TazKat


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I sure did mallani. I got dentures on top. I hate them. I finally had the roof of them cut out which makes it easier. will get retainer later for bottom for the back. it does do a number.



__________________

TazKat Genotype 1A null responder x 3 riba & iterferon twice, relapsed from Incivek 2012 with only 12 weeks left to do. stage 4 mild cirrhosis 4/25/2014/ started sovaldi riba & interferon.. finished treatment 7/17/14  results 7/25  cleared..

 

 
mallani


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Hi Duane,

I don't know anyone who's taken Interferon who hasn't had dental issues.

My tour of several dental labs has led me to the same conclusion. For the implant screws use Ti 6Al-4V ( that's 6% aluminium and 4% Vanadium) grade 5, or ELI (Grade 23). These are non ferromagnetic so I can still have my MRI. I agree that HA coating (HydroxyApatite) improves the integration of the implant into bone. Mine had the coating, and I also had some HA chips along one surface, as I have lost so much bone. Happy days.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Dzdayscomin


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What a coincidence that you would post this now, since I started and now finished my 12 week treatment of S/O I have broken 4 molars ....

At 1st I thought, well anyone can break a tooth, but after 4.... I'm thinking there has to be something to it, and having had the virus for some 30 yrs why now? So I asked the hepatologist today and he said nearly verbatum to what malcom said "dry mouth issues" and something about poor liver function and neutrophils.

Also found out at the dentist Tuesday getting the last two patched up , that I have what I think he said is a necrotic bone chip on the lower left lingual side gum by my last molar but it appears to be above the jaw bone structure and about a 1/4 " down from the gum line? You cannot see it on the xray but I can feel it and it is sharp enough to irritate and just a bit sore when I first noticed it poking thru the gum and sore I thought it was some filling material or part of my gold crown or something....so I grabbed my little diamond file boiled it and filed the sharp part off in about three strokes... (I make med devices for business so I know some stuff about that) then just did a good listerene mouth wash and shazamm no more pointy thing and the gum grew back over it. But I still had the dentist look at it and he refered me to the oral surgeon to take care of it.

Good topic and timing..I bet there are a lot more people that have dental Issues as a result of HCV and the resulting liver damage that have wondered why they were either breaking teeth or seeing more decay problems.

fyi implant screw material you are looking for is 6AL4V ELI titanium make sure its not from a chinese mill, it probably should also have an anodic treatment, and for best bone adhesion an HA coating that stimulates bone growth. If you ask your Implant surgeon those questions and he can answer them off the cuff he's good and knowledgeable about the product he is implanting. If he knows the Ti isn't from china he really knows his stuff because the only way you can actually know that is to have the original mill certification with melt lot....and that would only be in the implant OEM's and the supplier like "me" 's possession in the device history record.

 

Well better BRUSH MY TEETH and biggrin get some sleep 6 hrs till three month transplant labs and MRI...



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
jimbob


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I had a checkup 2nd month of tx. After reading this forum I also purchased Spry toothpaste and mouth wash at local health food store (per dental assistant's request) and ACT lozenges for dry mouth. Durung tx, I'd place one of these lozenges between cheek and gum and leave it there overnite. Haven't had a checkup since but I think it worked fairly well. CAUTION: I suppose there may be a chance of choking during sleep: however, I personally didn't have any problems, and didn't feel I would at bedtime. I was somehow always aware of it there, and it never moved.

Good luck.

__________________

jimbob: 64 y/o, GT 1A, F1-F2, diagnosed 1996. Since 1970. SOT 3.5 mil VL on 3/10/14 with Sov/Rib/Peg for 12 weeks. Tx naive. UND @ week 4,8,12. EOT 6/2/14.
JLynch30


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Yes, terrible dry mouth and gums bleeding.  I made sure i got a deep cleaning before treatment.



__________________

John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 
mallani


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Posts: 3398
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Permalink  
 

Hi all,

Every 6 months I do a post about the effect of HCV on teeth. Chronic HepC causes decreased, acidic saliva. This promotes tooth decay. For those patients who are put on Interferon, the problem gets worse. Interferon has a direct effect on tooth enamel, and further reduces saliva production.  Add the decreased neutrophils, and dental decay is a real problem. Back in the 1990's, this effect of Interferon was not mentioned. I lost 3 significant teeth from that experience. During my last 48 weeks of treatment, I still ended up losing 2 more teeth. This was despite a dental check prior to treatment, and 3 monthly checks during treatment ( although I missed the last one, as I was too ill). This will become less of a problem as Interferon disappears, and treatment times get shorter. However, get your teeth checked before treatment, use a mouth wash, and brush your teeth at least twice a day. I still have a dry mouth, so the damage to my salivary glands is probably permanent.

I have just had my final titanium screw inserted for another dental implant. I've researched implant types and cost and I'll do a post in 'Off Topic'.  Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
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