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Hep C Discussion Forum -> General Discussion -> Plant derived dietary components that impede HCV replication
Post Info TOPIC: Plant derived dietary components that impede HCV replication
wmlj1960


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RE: Plant derived dietary components that impede HCV replication
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Isiscat2011 wrote:

Hey Mike:  

Do you like oatmeal?  Very good for you and easy to prepare.  I eat it for breakfast almost daily and add blueberries or banana with some walnuts. Then I sprinkle on a couple teaspoons of Splenda brown sugar.  Add milk (You can use lactose free or sugar free coconut milk if you prefer).  

Get the old fashioned oats that you boil, or prepare in a small rice cooker, not the instant ones that contain lots of unnecessary sugar.  

I love me some nice hot oatmeal for breakfast!  

 

 Great idea. I know what your talking about because my mother made that for me when I was a kid. Quaker Oats. I liked it with butter, whole milk and lots of sugar as a kid but I can do it with nannas, bberrys, 1% milk, and I can use Lactulose for sweetening. (Believe it or not Lactulose is a great sweetener as long as you don't get it real hot such as boiling, broiling toast etc). Thanks for the idea Isis!!! smile



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Josh Haynie


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that seems accurate to me ... i take a half spoon of Turmeric a day and am proably going to order turmeric root so i can juice it to a better concentrated form .... though per say they arent as strong as DAA they certainly dont hurt..... I find herbs to be benificial ... they more or less hold it at bay untill you can get DAA so I deffinetly say go for it.. thats why my biopsy on monday will be very telling 

 

 



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Huey


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I agree, I like Aloe Vera  however this is the same science



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Isiscat2011


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Hey Mike:  

Do you like oatmeal?  Very good for you and easy to prepare.  I eat it for breakfast almost daily and add blueberries or banana with some walnuts. Then I sprinkle on a couple teaspoons of Splenda brown sugar.  Add milk (You can use lactose free or sugar free coconut milk if you prefer).  

Get the old fashioned oats that you boil, or prepare in a small rice cooker, not the instant ones that contain lots of unnecessary sugar.  

I love me some nice hot oatmeal for breakfast!  

 



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wmlj1960


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 That's valuable information for me, since recent changes have placed me 'only' in charge of preparing meals for myself. And I have very little kitchen experience. I eat a lot of grapes or some fresh blueberry's every morning on raisin bran flakes cereal, and have been drinking ~ 1 1/2 gallons of decaf green tea daily since last January.

 You stated,

I would hypothesize that including them in our diet before treatment and after treatment could be beneficial. Curcumin (turmeric) has many other health benefits as well.

I agree with 'before and after Tx', but is there a reason you did not include 'during Tx', at least for grapes, blueberry's and green tea.

Thanks for the helpful post Matt Chris! smile

 



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60 yo, geno 1a, Dx 1994 HCV-HIV co-inf, Dx 2013 decompensated cirrhosis
Tx #1 - 24wks Sov+Riba /SOT 7-24-2014/UND@EOT/DETECTED@EOT+16 wks
Tx #2 - 24wks Harvoni /SOT 7-25-2015/UND@EOT,+12,+24,+52 = SVR

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Matt Chris


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Hey all

Ran across a small article from the Hepatitis Central web site on Pomegranates, which caused me to dig deeper to find the authors of this study from India and the paper that was published in the Nature.com web site.

Here is a small excerpt from the article and to link below to the full article

A vast majority of natural components or dietary components are capable of modulating mitogenic signals, cell cycle regulation, angiogenesis, apoptosis and metastasis4. Few of the plant derived dietary components have been explored for their abilities to interfere with all possible stages of HCV life cycle via different mechanisms and proved valuable to HCV therapy. Recently, naringenin (grapes) has been shown to inhibit apolipoprotein B-dependent secretion of HCV particles5. Proanthocyanidin (blueberry) suppresses HCV replication, possibly by interacting with hnRNP A2/B6. Curcumin (turmeric) inhibits HCV replication via suppressing the AKT SREBP-1 pathway7 and entry of all HCV genotypes into human liver cells8. Epigallocatechin-3-gallate (green tea) inhibits HCV entry9. Also, its phenolic epicatechins (+/) inhibit HCV replication via cyclooxygenase-2 pathway10. Similarly, quercetin has been shown to inhibit HCV by targeting the cellular heat shock proteins, HSPs 40 and 7011. It also abrogates the HCV NS3/4A protease activity in vitro as well as ex vivo

 

Link- http://www.nature.com/srep/2014/140624/srep05411/full/srep05411.html

Its seems obvious to me that the strength of these plant based HCV inhibitors can be appreciated but the in comparison to Sofosbuvir and other DAA's they still lack in power to eradicate the HCV totally. I have tried most of these plant based items (herbs) and found them to help in controlling the high viral count and alleviate a portion of fatigue that can accompany chronic HCV.

I would hypothesize that including them in our diet before treatment and after treatment could be beneficial. Curcumin (turmeric) has many other health benefits as well.

Someday they may discover the really powerful plant based herb or combination of herbs to fight HCV but for now we will have to rely on big Pharma for the big guns.    

matt 

 



-- Edited by Matt Chris on Thursday 7th of August 2014 07:19:15 PM



-- Edited by Matt Chris on Thursday 7th of August 2014 07:22:04 PM

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