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Hep C Discussion Forum -> General Discussion -> Sofosbuvir + GS-5816
Post Info TOPIC: Sofosbuvir + GS-5816
robertsamx


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RE: Sofosbuvir + GS-5816
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Thanks tig, gs5816 looks like my only option W/solv-most likley W/riba.  Cant wait to go down the riba road again. (not really)   RC



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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
Tig


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Hey RC,

No name that I've seen discussed yet. As long as it remains in trials, the name is kept secret for marketing and patent rights.

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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I wish I could get into this trial  NCT02201953  but its randomized and one arm is W/O gs5816  Does GS5816 have a drug name yet?   I cant find any info on it??  Thanks all  RC



-- Edited by robertsamx on Sunday 14th of December 2014 05:56:17 AM



-- Edited by robertsamx on Sunday 14th of December 2014 06:03:56 AM

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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
mallani


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Hi Tig,

Good article and it gives hope to the Rx-failed Geno 3 cirrhotics.

I guess Gilead will co-formulate Sovaldi and GS-5816 into a single pill, so that will be another interesting pricing decision.

At last we're starting to hear about RAV's at the NS-5A site. More to come I hope. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Tig


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Interesting article on the newest pan-genotypic protocol in development. Is this the answer? For those interested, there is a link at the bottom (of artiicle) to the Clinical trials website with info on the current "Astral 3" study underway. We have discussed this before but the new articles provide insight and hope!

http://mobile.aidsmap.com/Sofosbuvir-GS-5816-for-12-weeks-shows-high-HCV-cure-rates-but-8-weeks-is-less-effective-for-some-patients/page/2923542

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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