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Hep C Discussion Forum -> Clinical Trial Participants -> Metformin
Post Info TOPIC: Metformin
JimmyK


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RE: Metformin
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Ok then make it a LARGE Diet Coke!

By the way what is up with that? no



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Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

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wmlj1960


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Nope. A 2% cow would be an insult to those Cinnabon's, kinda like a double cheeseburger with the works, large fry, blueberry turnover and a 'DIET' Coke. biggrin



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60 yo, geno 1a, Dx 1994 HCV-HIV co-inf, Dx 2013 decompensated cirrhosis
Tx #1 - 24wks Sov+Riba /SOT 7-24-2014/UND@EOT/DETECTED@EOT+16 wks
Tx #2 - 24wks Harvoni /SOT 7-25-2015/UND@EOT,+12,+24,+52 = SVR

Mike

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Linuxter


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Hey Mike,

That's not one of those "Skinny Cows" is it ... that just wouldn't be right with Cinnabons confuse

... that one there's a down right friendly looking cow, gotta admit. smile



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63yy,HCV,2b,F3-A1, Sof/Riba,12wks Tx   SOT: 1/20/16, HCV-RNA 9,816,581, ALT 56, Hb 14.6

4wk: HCV-RNA <15 Detected, ALT 15, AST 17, Hb 13.6 EOT: 4/12/16, ALT 18 , Hb 12.9176a2f85d05d9c965eafe199f2ba9ba5.jpg SVR Achieved 7/8/16

 
JimmyK


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robertsamx wrote:

I'm sending out a S.O.S.   I need a CINNABON    SEND HELP!!   Ragdoll is starving me . I'm withering away to my formal self. I thing this foot surgery thing was her idea to get my blood sugars and weigh down, I'm stuck in my recliner, HELP!!   Send snacks please!!   RC

 Brother I think I have just the thing.

FreeToes!

 

The no



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Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."
wmlj1960


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How about a cow too to get you through the week. biggrin

Milk cow.jpg



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60 yo, geno 1a, Dx 1994 HCV-HIV co-inf, Dx 2013 decompensated cirrhosis
Tx #1 - 24wks Sov+Riba /SOT 7-24-2014/UND@EOT/DETECTED@EOT+16 wks
Tx #2 - 24wks Harvoni /SOT 7-25-2015/UND@EOT,+12,+24,+52 = SVR

Mike

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robertsamx


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OOOO YES!  That was what I needed! Just the right amount of frosting too. Honey can I get a glass of milk to go with that??  RC



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Tig


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Here ya go Brother, don't let Ragdoll know and our secret is safe!

image.jpeg



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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I'm sending out a S.O.S.   I need a CINNABON    SEND HELP!!   Ragdoll is starving me . I'm withering away to my formal self. I thing this foot surgery thing was her idea to get my blood sugars and weigh down, I'm stuck in my recliner, HELP!!   Send snacks please!!   RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
RAGDOLL


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Great information,  RC has the IR thing going on and got much worse during last round of treatment which was expected.  We will defiinitely file this info and watch. May ask Dr, about all this on Monday during screening.  Everything back in control right now with insulin and strict diet.  Since foot operation I am in control of the menu! Lol



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F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years, 2022 7 years!
Shadowfax


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Hi Canuck,

Interesting post to be sure. I was told in 2001 that I was diabetic and started watching my diet. I monitored my sugars and went to the hospital to learn about it all. Before the end of one week, the hospital said, We don't know why your Dr. said this, your values post meal are perfect, your A1C is perfect. It seems that I am really as they said glucose intolerant.

That being said, I was always aware and would randomly check myself after going through 6 months of checking 4 times a day and writing down absolutely everything I ate.  Of course year physicals would check as well. I knew that stress would raise your blood sugar just like it does your blood pressure.

Last April, my doctor now said I might consider taking Metformin based on being higher in levels but still not over them. I still have the prescription and never took them because my home results are still fine. In April we will see my new results and I have changed my diet.

 

 



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65 yo, GT1A, , Cirrhosis, F-Scan F4 33.5, TX Naive Harvoni 12 wks

SOT 2/9/16 / ALT 187 AST 114 VL 2.3M.    POSTS

EOT 5/2/16  ALT 35/ AST/25  platlets 126 C/B VL UND

EOT +12 7/26/16  ALT 25 /AST 22/ ALP 83  platlets 129 C/B VL UND

EOT + 24 10/18/16 ALT 27/ AST 20/ ALP 71 platlets 153 C UND

 * SVR *
Linuxter


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Hi Canuck,

I too was Dx as "pre diabetic" so this is quite interesting.

I did see that with my 4 week lab results, for the first time in years my glucose level was within range.

I won't be too quick to jump to conclusions since the Sov/ Riba may have some direct effect on glucose levels.

'Twood be nice to see that glucose level remain within range after SVR as well and know, in the back of my mind that drugs are being studied now that may help stay in range if need be.

Always like to try to control what's within my power via nutrition, exercise etc but it's reassuring having a backup plan if necessary.

 

Thanks,

Dave 



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63yy,HCV,2b,F3-A1, Sof/Riba,12wks Tx   SOT: 1/20/16, HCV-RNA 9,816,581, ALT 56, Hb 14.6

4wk: HCV-RNA <15 Detected, ALT 15, AST 17, Hb 13.6 EOT: 4/12/16, ALT 18 , Hb 12.9176a2f85d05d9c965eafe199f2ba9ba5.jpg SVR Achieved 7/8/16

 
Tig


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This is interesting Canuck. I was pre diabetic at one point and fortunately my glucose levels have returned to normal since SVR. I'm sure there's a connection between HCV and insulin/ glucose levels, so these studies can be quite useful and informative. Thanks!



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Canuck


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Just in passing, found this a little interesting about them exploring metformin.

https://clinicaltrials.gov/ct2/show/NCT02306070?term=hepatitis+C+AND+Canada&recr=Open&no_unk=Y&rank=30

Canuck

 



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

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