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Post Info TOPIC: Hi


Guru

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Welcome aboard

You certainly found the right place for answers to pretty much any question you have. Most protocols have been take and discussed so in particular the search button at the top of the page would be great benefit if you want to find something in particular.

Now that you have started Harvoni, you may want to peek at this thread dedicated to that. Once again welcome and wishing you luck on your 24 weeks

http://hepcfriends.activeboard.com/t58762824/all-aboard-for-the-harvoni-treatment-train-enjoy-the-ride-fo/



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65 yo, GT1A, , Cirrhosis, F-Scan F4 33.5, TX Naive Harvoni 12 wks

SOT 2/9/16 / ALT 187 AST 114 VL 2.3M.    POSTS

EOT 5/2/16  ALT 35/ AST/25  platlets 126 C/B VL UND

EOT +12 7/26/16  ALT 25 /AST 22/ ALP 83  platlets 129 C/B VL UND

EOT + 24 10/18/16 ALT 27/ AST 20/ ALP 71 platlets 153 C UND

 * SVR *



Guru

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Hi Hangerd,

it must have been really disappointed after such regime to find that the virus was still there with you.

everyone says that Harvoni has a very high success rate and hopefully you will hardly know you are on treatment compared to last year.

i am up to week 14 of Daclinza, Sofisbuvir. I also took Ribaviron for 12 weeks but couldn't keep going on it. I hope it won't effect the outcome. 

Good luck, 

this forum makes you feel, not only that you are not alone, but also that there are so many people in far worse situations who can be positive, inspire others, support family members and still retain a great sense of humour. It's very humbling.

Syd



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Contracted Hep C 1969. Genome Type 2, treatment naive. Began 12 week RIBA/sof/Dac on 12/11/15. Cirrhosis. VL before treatment 4m. Treatment extended another 12 weeks without Riba. No virus detected at 9 weeks.



Guru

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Hi and welcome.

Hopefully the 24 weeks of Harvoni will be successful for you.

The Viral Load during treatment is never 0. It may be Undetected but the Undetected level depends on your Lab.

Also, residual virus doesn't only hide-out in the liver. It may be in virtually any tissue, but particularly in lymph and blood monocytes.

Best of luck. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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hangerd wrote:

Hello guys! Glad to be a part from this community! Hope to be helpful! :)


 

hangerd wrote:

With genotype 1 Hep C, I took the Sovaldi/Ribavirin/Pegylated Interferon for 12 weeks this past summer. There was 0 viral load after 4 weeks. 0 after 12 weeks, after I had finished taking the drugs for all 12 weeks. After 9 months, the viral load returned at 1,496,000. I engaged in absolutely no behavior that causes Hep C - no needles at all, no sex at all, no drugs at all; I did not drink any alcohol. My doctors' only answer is that the cirrhosis of the liver was so bad (compensated cirrhosis) that not all of the virus was cleansed out of the dead parts of the liver with just 12 weeks of Sovaldi.

I am now on the Harvoni for 24 weeks, hoping that the longer regimen of the two drugs - Sovaldi and Ledipasvir - will totally clean out the virus from the liver.


Hi Thom and welcome from me as well. Your doctor is likely right about cirrhosis being the reason 12 weeks did not produce a sustained viral response last time. From what I've seen 24 weeks of Harvoni should do the trick for you. I am also cirrhotic and failed Sov / ribavirin Tx in 2014 then re-treated with 24 weeks Harvoni this past year. I won't have a final EOT+12 weeks viral load test until April 7, but all indications right now point toward Harvoni being my silver bullet cure. It can happen for you too, just be sure to help the medicine fight by taking care of your body while on treatment. Stay adequately hydrated with 3-4 liters of good water daily, eat reasonably healthy, get some exercise but don't overdo it, and rest your body well. The side effects of Harvoni were very tolerable for me and will likely be so for you.

 So good luck with your 2nd and final battle and keep us up to date on how everything is going for you. smile



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60 yo, geno 1a, Dx 1994 HCV-HIV co-inf, Dx 2013 decompensated cirrhosis
Tx #1 - 24wks Sov+Riba /SOT 7-24-2014/UND@EOT/DETECTED@EOT+16 wks
Tx #2 - 24wks Harvoni /SOT 7-25-2015/UND@EOT,+12,+24,+52 = SVR

Mike

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Hi Thom,

Welcome, nice to have ya here!

Lots of great information and wonderful folks here, you'll be glad you landed here ... this site is a blessing and has helped us all, from pre-treatment through treatment (Tx), re-treatment as may be the case as well as post Tx. Very helpful bunch here.

Make yourself at home, tell us about yourself and as already noted, ask any questions you may have or hit the Search button (top center).

 

Welcome,

Dave

 



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63yy,HCV,2b,F3-A1, Sof/Riba,12wks Tx   SOT: 1/20/16, HCV-RNA 9,816,581, ALT 56, Hb 14.6

4wk: HCV-RNA <15 Detected, ALT 15, AST 17, Hb 13.6 EOT: 4/12/16, ALT 18 , Hb 12.9176a2f85d05d9c965eafe199f2ba9ba5.jpg SVR Achieved 7/8/16

 



Guru

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Welcome to the forum Thom!     Sorry to hear about your relapse.  The 12 week treatment SOD-RIBA-PEG is tough to get through.  Sounds lke you and your team have a plan forward. I see your a type 1   Do you know if the sub is A or B.  Tell us a little more about your self and we can be more helpful.  There are lots of new drug combos on the market and coming to market soon. This is a good time to get treated for hepc.  Any questions you have just ask away and someone on the forum will be along to help answer them.  RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   



Guru

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HI Thom, welcome!

Could you tell us a bit about your situation, please, regarding your Hep C and whether or not you are currently on treatment?  A few details would enable us to reply to your introduction here.

Let us know if we can help with anything.  Note that we have a `Search` box at the top of the page if you`re looking for any particular information, or just ask!  smile 

 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



Newbie

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Hello guys! Glad to be a part from this community! Hope to be helpful! :)



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