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Post Info TOPIC: VIRAL LOAD - CONVERSION TO "LOG"
Tig


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VIRAL LOAD - CONVERSION TO "LOG"
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Good info Canuck! Here is a link to a calculator one of our members provided us. Once there, be sure to clear the fields as mentioned in my post. For some reason his numbers remain, just erase them. 

Log Calculator thread

Shortcut to his calculator



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

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VIRAL LOAD - "LOG" CONVERSION

 

When the lowest limit of detection used is <12 IU/mL = 1.08 log 

 

When the lowest limit of detection used is <15 IU/mL = 1.18 log  (as described below, 15 to 100 million)

This assay has a result range of 15 to 100,000,000 IU/mL (1.18 log to 8.00 log IU/mL) for quantification of hepatitis C virus (HCV) RNA in serum.

An "Undetected" result indicates that the HCV is absent in the patient's serum specimen.

A result of "<15 IU/mL (<1.18 log IU/mL)" indicates that HCV RNA is detected, but the HCV RNA level present cannot be quantified accurately below this lower limit of quantification of this assay. When clinically indicated, follow-up testing with this assay is recommended in 1 to 2 months. To assess response-guided therapy eligibility, an "Undetected" result is required, and a result of "<15 IU/mL mL (<1.18 log IU/mL)" should not be considered equivalent to an "Undetected" result. 

A quantitative result expressed in IU/mL and log IU/mL indicates the degree of active HCV viral replication in the patient. Monitoring HCV RNA levels over time is important to assess disease progression and/or monitoring a patient's response to anti-HCV therapy. 

A result of ">100,000,000 IU/mL (>8.00 log IU/mL)" indicates the presence of active HCV viral replication, and the HCV RNA level present cannot be quantified accurately above this upper limit of quantification of this assay.

 

Example conversions: IU/mL to log

 

http://www.hepatitiscentral.com/hcv/hepatitis/loadchart/



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

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