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Hep C Discussion Forum -> Knowledge/Info Section -> About becoming UND slowly
Post Info TOPIC: About becoming UND slowly
Lindsmatt52


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RE: About becoming UND slowly
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Tig-Thank you for explaining that again.  No many how many times I hear that it's okay if you don't get UND in the 4 or 8 week blood draw, I always appreciate having it repeated.  Eventually, it will sink in!!biggrin



__________________

64 y/o female, no idea how HEP C contracted

diag. 6/2017, GT 1a, VL 7.64 mil

Fibrotest-.41 (F1-F2) ; Actitest/Metavir 0.18; Apri: 0.266

Mutations detected: Q30H/Y, H58Q

Alt-33;  Ast-28

4 week:  VL<15; ALT-7 AST-11: 8 week: VL-UND, ALT-9, AST- 9

 Epclusa SOT 8-31-17; EOT 11-22-17

Lindsay
Tig


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I have seen this slow roll out to SVR occur in members here. It has to be difficult to see others reach the big ZERO in 4-6 weeks and you be either quantified or <15 but detected. The truth is, it happens more than you’re aware. This is one reason why some doctors won’t do a viral load until 12 weeks post treatment. If the CMP/LFT’s fall back into a normal range and stay there, in addition to a downward spiraling viral load, you’re in good shape. It’s not an easy realization to accept, but it’s true. I think it’s good to know and not something many are aware of. We always hear about the 4 week (some even 2) wonders, but rarely do we hear about people celebrating this scenario. If this happens to you, the reader, remember it and don’t despair. 



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Canuck


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Recent article (and studies) about having a detectable load at EOT, or being "slow to become undetectable" during DAA treatment - that it does not equate to mean the patient will not reach SVR. Most do go on to being SVR.  (Article draws from a couple good reference studies - the subjects analyzed had done a variety of DAA therapies, sof-based, such as sof/ledi, etc.)

 

http://www.practiceupdate.com/c/58783/2/9/?elsca1=emc_enews_daily-digest&elsca2=email&elsca3=practiceupdate_gastro&elsca4=gastroenterology&elsca5=newsletter&rid=MjQyNzU0MDE2NjM3S0&lid=10332481

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

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