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Post Info TOPIC: Post Tx aches and pains


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RE: Post Tx aches and pains
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I'm not much of a fan of supplements etc.

However, my Rheumatologist said he takes fish oil. I thought that was good enough for me, and I've been taking it ever since. Perhaps it helps. You do need a decent dose, ~3000mg of Omega-3 per day.

I've also started taking a Magnesium supplement, when I'm playing golf on a hot day. It's said to reduce muscle cramps and spasms. It seems to work.

Pilates is also said to be the best way to stretch ligaments, muscles and tendons. All my golfing mates do it 3 times a week. I'm not that desperate yet. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm



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I just got a "reply-to" email notice regarding this thread, which is still relevant in my life as I'm still pursuing strategies for minimizing the myalgia and maximizing a re-constructive exercise regimen.

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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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Hi all,

We are aware that HCV is associated with a variety of annoying problems. Arthralgia (pain in the joints), myalgia (pain in muscles) and fibromyalgia (pain in joint capsules and tendons) are all common. Whether this is autoimmune or due to direct action of the virus doesn't matter. We are stuck with it. The important thing to eliminate is Rheumatoid Arthritis. If you go all the way back to my original post on this thread, I list the various blood tests necessary for this.

Interferon also causes 'reactive' arthritis, which causes very similar symptoms to RA. These problems ease with time, but in my case, it took a year.

The good news is that SVR brings an improvement in the various joint and soft tissue problems, but again this takes time. Exercise helps greatly. Occasional use of low dose NSAIDs like Meloxican also helps.

Remember we're all getting older, and our joints and muscles are too. We are also more aware of any body changes after treatment, and tend to worry more about things like 'arthritis'.

If you're really concerned, get a referral to a Rheumatologist. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm



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I completed 24 wks of treatment with Sovaldi and Riba on Oct 18. On some days I feel as though I'm 80 years old. My joints and muscles ache so bad. My bedroom is on the 2nd floor and my knees now hate steps. Even my ankles hurt. I am now living in NC, and have to purposely exercise, different than NY where just living is exercise. So now, on most days, I walk between 4 and 5 miles. Today is a good day. No aches...no pains. I read in one of the threads that if you don't use it you will lose it. So I guess that means I must remain active, drink much water  and eat as healthy as possible.



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DJ...dx 2005...geno 4c...twice interferon/riba failure....completed 24 weeks Sovaldi & Riba on 10/18/14....SOT VL 600,000 after 16 days VL <43. Day 45 <43 again. Day 59...8 weeks UNDETECTED.

Happy and grateful to God for new life....



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As I read all the posts, I don't feel so all alone in my pain. What is different is that I actually got a diagnosis. Fibromyalgia, which is chronic, very manageable and is common with Hep C patients.



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I have your exact problem but tested negative for thyroid, rheumatoid arthritis and inflammatory disease. I was diagnosed with Fibromyalgia, which studies have linked to Hep-C. I have gotten great relief with a small dose of Elavil and exercise with yoga.

I treated successfully in 2012

congrats and I hope you are feeling better 



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Hey All!  It's been ages since I've been in here and 2 years since I started treatment!  I finished in July 0f 2012.

My joint pain was severe and has been addressed by way of thyroid treatment.  I have hypo-thyroid, which is very common among us post-treatment folks and though it's not always advertised, low-thyroid can cause joint pain and plantar fasciitis, which is foot pain that is worst at the end of the day after you've been on your feet, then sit for a bit and get up and walk...ouch!  It's also painful first thing in the morning.  

I am currently on Armour thyroid, which is a naturally -dissected pig thyroid that my endocrinologist isn't crazy about because it's inconsistent in it's potency, but it has worked better for me than synthroid did.  (synthetic version)

I do still get joint pain, especially in my knees.  But NOTHING like it was about 1 year post treatment.

The plantar faciitis is still an issue, being addressed with custom orthotics and the thyroid meds, but that's a slow one to heal (no pun intended)!

Remember this is a tough treatment to recover from and it's slow.  Healthy diet, exercise, and addressing those issues as they come up will help you see the light.  You will get fluffed off from time to time, but be persistent!  



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wilsondog


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I need joint pain relief too.
Had it before treatment but it was not
Constant. My right hip, elbow and feet hurt
Daily. I made SVR.
I like being active!
Best wishes to all.

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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!



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Thanks hrsrtrdr. I have achieved SVR and am blessed from it. Never would have dreamed of having these aches and pains although All I can get out of my Doc is that I have osteoarthritis. My GI will not see me but by email only and does not feel any of this is caused by the treatment. I have a visit with the orthopedic doc on Thursday. What should I expect or ask? l

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Hi drtminor, welcome to the forum. Whether or not these muscle & joint pain and stiffness problems are permanent or will go away- it's hard to say. I am 16 months post tx and still struggle with these issues daily, but I have hopes that "in time" these matters will resolve. Maybe not 100%, but hopefully; no one knows(or could know) for sure.

I try to relieve the pain with minimal poses of OTC meds such as Tylenol and Ibuprofen; heating pads work really well. I try to keep fit with muscle toning exercise, as far as I can, without aggravating existing joint & muscle discomfort.

Good luck, I hope your post tx recovery goes well.

Q: Have you attained SVR?

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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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I am new to the forum and have been off Hep C triple therapy for close to 10 months.  I am experiencing severe pain in my left hip, left thigh and lower back.  The worse pain is that sharp pain in the middle of my left thigh. The doc says it is arthritis in my hip.  I went to physical therapy and that helps some. My daily stretching is helpful but requires a lot of discipline--without any long term impact (for most days I have this severe pain). Some days are worst then others but never to the point where I can't function.  I do office work so I sit all day. However, I am very active and will not allow this to keep me down. I have been on Tramadol which works, but I am very concerned about the hepatic side effects (purported) and the possibility of addiction. I alternate days with Advil and Tylenol with some relief.  I have read in the forum that this pain may pass or go away after 12 to 18 months post treatment.  Any truth to that or I will I have this condition forever?



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hope you are doing better Teddy, I experience the same but my breath has come back but sweats etc do come back, I guess they were right and it will take time to recover, joint pain is getting better I use a herbal and it took a while to kick in but seems to be getting better, message me and I will give you the name, good health to all

bill and the girls



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Geno type 1  rib and peg September 2012 , 5 weeks tripple and viral down to < 15 und april Aug 25 finished stay at peg 3 rib and eprex + blood transfussion finished treatment Aug 25 2013



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All of my joints have really been very painful this last week. I was really feeling quite good about myself and  how well things where returning to normal. I have gotten really realty cold here this lasts week -38 C >  with the wind chill and we have had 12" of snow in two days. I shoveled out the porches and the sidewalks 3 times during the storm and felt really good about how I managed to complete the job and didn't hurt and had no problem breathing and suffered little fatigue. Then this Tuesday I had insomnia and it got worse from there. Then my world crashed and burned. 3 days ago I had the Feds come on Thursday and do a census interview on my living standard over the last year at 1 PM and it took until 3:30 PM to complete. It had really caused me to grow weaken with intense brain frogs and to suffer waves of fatigue to come upon me near the end of the interview. The workers battery on her notebook died and the Federal program didn't have a auto save and she lost all the data. We decided to re due the interview by phone the following day. That evening a dear friend took me out to watch the Olympic Canadian Curling trials. The weather had turned really ugly with -45 C with gusting winds. I dressed for it and only had to walk 2 city blocks to the arena but I was overcome by the weather and stared to recede back to the treatment SX days. I watched the event and made it back to the car and home. I relapsed back to the how I felt two months ago. I spent the rest of evening in bed and slept 20 hrs. I had to change mt night clothes twice as they were very wet, I couldn't breath and wheezed all night. My mouth returned to being very dry and my  flem  dried  in my throat and mouth and I had a bit of a panic attack as my puffers didn't help much. Every breath I take is a wheeze and hasn't let up. I fell so miserable and I guess a bit frighten That my lungs won't clear and  I'll have to carry a Oxygen bottle strapped to my back and  my life will be worse off than before this hellish 48 weeks of treatment. I can't sleep because I'm wheezing so loud with every breath. I just feel like I'm right back in treatment SX I feel so miserable and depressed and I'm sorry to lay this on you all.     



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Lady, great to see you on the forum! You were my inspiration

that a woman could survive 48 weeks of treatment.  

Now we are both SVR! So grateful!

I am having joint pains etc... Worse

than ever as in I don't want to exercise by walking. 

Hope we improve soon! 

 



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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!



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Terry, you know that is funny. I also used to get fever blister occasionally, a lot of times it was associated with stress, and I cant remember the last time I had one, its been years. Would be just one little added benefit. Haha. I guess this stuff is all anti-viral so maybe we are all getting benefits we don't even know about. Good luck, hope it cures all that ails ya!!
You would have to be a heck of a salesman to market this stuff as a herpes cure though.

-- Edited by newmex on Wednesday 4th of December 2013 02:21:45 AM

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John


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Funny all of you should be mentioning the disappearing ailments because I used to see a chiropractor every month or two and also have had a mild case of herpes that for anyone that has had it usually shows up when you are run down or very stressed. And I have been both but since I started treatment I haven't been to my chiropractor or seen the herpes since. And you can't get more stressed then during treatment so is it possible that the drugs killed that virus at the same time ?

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Geno Type 1a stage 4 cirrhosis EOT 52 weeks SVR !!



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Tig56 wrote:

I had real problems with gout too. I never attributed it to HCV though. I am convinced or was, that it was due to my lifestyle and diet. It got so bad I couldn't walk at times. I also got relief from Indomethicin and ultimately was prescribed Allopurinol for it. Once I started HCV treatment I was getting quite ill from the various meds I was taking, so I stopped taking most of them and the nausea stopped. I haven't taken anything for gout since June and haven't had a bad flare up since. It would be nice to think that the triple therapy has stopped or improved some of my other ailments as well.


Cant comment on end of treatment yet, have only been on peg/riba for a month, but have had pain in hands and finger especially for years. Since I have been on the meds pain and swelling  has been reduced by probably at least 75%. Don't know for sure if its from meds,  slowing down on work or combination of the two. I'm hoping that its a symptom of the hep and as I eliminate it a lot of problems will go with it. So far so good

 



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John
Tig


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I had real problems with gout too. I never attributed it to HCV though. I am convinced or was, that it was due to my lifestyle and diet. It got so bad I couldn't walk at times. I also got relief from Indomethicin and ultimately was prescribed Allopurinol for it. Once I started HCV treatment I was getting quite ill from the various meds I was taking, so I stopped taking most of them and the nausea stopped. I haven't taken anything for gout since June and haven't had a bad flare up since. It would be nice to think that the triple therapy has stopped or improved some of my other ailments as well.



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Tig

61 yo GT1A - 5 Mil - A2/F3 - (1996) Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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Malcolm et al,

Thanks for this thread.  I had gout attacks a few years ago, prior to tx, but did not had any during the 48 weeks, except for the last week of tx. I had a gout flare-up and took course of Indomethicin which I had from previous treatments and felt relief from pain and swelling.....flared up again last night, started another course of Indomethicin and will be seeing GP and gastro in next week or so.

Finished  48 weeks of tx last Friday (Nov 29) and wondered of this was a sx from the treatment - will continue to monitor it all and see where we go from here.  Thanks for the info on other NSAID's and I will be asking about the best course of tx for the gout and possible dietary contributing factors.

Any information along these lines would be appreciated.  Thanks for all your expertise with this and your willingness to share.

Bill



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1a, 35+ years; liver cancer survivor 7-2012 surgery; triple therapy 12-2012 (Interferon, riba, victrelis) - end 48-week treatment Nov. 29, 2013 - post tx 24 weeks undetected - SVR.



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Malcolm,

Thanks to you (& everybody) for the warm welcome, this thread is exactly what I've been looking for. I've just turned 44 (have not gone through 'the change') no history of RA or osteoporosis. I have another appt. with my orthopedic surgeon on Friday, then the endocrinologist on 12 December, I have noted down all the above to ask if they will be checking for that in addition to measuring bone density. It's just so strange, fortunately, I was never acute with HCV, just chronic, never sick (even though PCR's prior to treatment showed HCV active in my liver).

The side effects of the treatment at the time (living in Ireland) were ****e (if you'll pardon the vernacular) but again, was fortunate that I could still work (did my weekly injection on a Friday after work, so would be *really* sick all weekend, then just *normal* sick (but able to cope) taking the copegus ribavirin capsules daily. I experienced no bone symptoms at the time, & cannot recall being advised at the time that might be an issue. The main concern Prof. Hegarty & the team at St. Vincent's had was depression, as one person being treated at the Liver Unit there committed suicide. I was in my mid 30's when I started the combined therapy, started Jan 2004 & completed in Feb 2005 (EU approval in 2002).

It's only been over the years, I'd get these mad flare ups of pain in my back (lumbar region), knees, hips, neck (cervical), wrists, etc. They'd come and go....then I moved to the US had my two children (daughter, turned 5 in November & son turned 3 at the end of October). And starting at the end of last year, my bone pain just got worse & worse, I thought it was just me, from gaining so much weight during the pregnancies (11 days after my daughter self-weaned, I got pregnant with my son) & I was an "old" mum. But I lost the weight after my daughter, but found it harder & harder after my son, but did lose most of the weight & am continuing to do so....so I went to the OMM (for osteo treatment) chiropractor, regular GP etc....and when it would go away in the past it just didn't this time...culminating in two events -  Halloween this year we walked for about 2 hours (in the rain) but my 3 year old was really into it this year, but by the end I could barely walk.

The next day Friday, 01 November, I was in the baby aisle in Walmart, hubby was in the car park with the children, all I had to get was 5 things (the next day was our daughter's first 'real' birthday party with friends from pre-school), I turned (full body) picked up a box of baby wipes (didn't have to bend, it wasn't too heavy), turned to go walk to get rubbish bin liners when there was this 'pop' (which was my pelvis fracturing) it was quite audible actually, no initial pain - for about 5-10 seconds, very surreal...then I thought I'd throw up the pain was so bad & I couldn't walk, couldn't move at all. Thank goodness I had a mobile phone on me to ring hubby to come to the rescue...& we went to the ER (after ringing GP & chiropractor).

And it seems like things are accelerating quite rapidly - bone / pain wise. The morning & evenings are the worst, but it's pretty much constant pain, and you can hear me coming (all the popping / cracking) & everything hurts now, all the time. Obviously the pelvis (right side), my lumbar & cervical regions of spine, knees, hips, elbows, wrists, ankles, feet, fingers....and to top it all off, I'm allergic to aspirin & all NSAIDS...so they have me on 5mg of oxycodone & I supplement with Paracetamol (Tylenol)....it doesn't even take the edge off, but I don't want to be on pain meds forever....and other forums I just browsed (but didn't join) had quite a few people complaining of post Rx bone pain that would accelerate quite rapidly even after a lengthy time after treatment....It wouldn't be so bad if it was just me...but trying to take care of a 5 & 3 year old (I'm in New England & have no family here)...is a bit difficult...not only am I the oldest mum at the school gates, but now I hobble about with a walker...sorry for the long rant, thank you again for the above, best wishes & good health to all. Jenny



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The gout is 98% gone. I thought for sure it would take a week as it was well swollen and turning that ugly rosy red. Back in 99-01 I suffered increasable amounts of pain and had it for weeks on end. I remember going to the emergency at our little hick hospital and was in almost non stop screaming for 3 hours waiting for the doctor to get there and give me a shot of extra large dose demurral. I was on that 3 times a week shot treatment and was told I could not take drugs to alter my gout while I was on the experiment trials. Living 500 miles north of Winnipeg didn't help at all and the Doctor that started me on it disappeared to practice in the states so I had no one to monitor any of my levels  during the treatment, I was  lucky I didn't kill myself.

What an huge change 13 years has made in medicine and treatment knowledge. These new drugs that has come to market since that time sure has made a difference in all of our lives and health out comes. Cheers every one.    



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Tig


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Thanks Malcolm, I don't take it regularly and actually haven't had to for awhile now. It does the job very well though, but as usual the products that work are the harshest on our systems! What we won't do to play another round, lol! I'll definitely keep your advice in mind. I appreciate your help!



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Tig

61 yo GT1A - 5 Mil - A2/F3 - (1996) Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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Hi Tig,

Indomethicin is one of the oldest NSAIDs and can be pretty toxic to the stomach lining. You should always take it with food, and try not to take it regularly. I'm sure it's effective, but I prefer Mobic, a second generation NSAID.  I still take one when I am playing golf two days in a row. They are all metabolised in the liver, so I'm very cautious in using them. Although I'm slowly improving, I still get some stiffness and knee pains after a lot of exertion. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm

Tig


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When I was having gout flare ups, my doc prescribed Indomethicin 50mg 3 x day and it was golden for that type of pain and it also gave me great relief for joint pain in general. It's in the same class as Naproxen but gave me better results when I used it. I ended up taking Allopurinol for the gout on a daily basis, which worked very well. I stopped taking that after I noticed it was making me nauseous when I started the current HCV triple therapy. So far my uric acid levels haven't re-elevated since quitting the Allopurinol. You might mention the Indomethicin to your doctor for that occasional joint pain. It works very well for me when needed!



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Tig

61 yo GT1A - 5 Mil - A2/F3 - (1996) Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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Yes thanks for the post. I have had a great deal of problems, not just pain, since my first treatment in 99. It took many years to find a good physician that has actually taken the time to help me through my aches and pains. I have a 6 different specialists now keeping my body parts working. I am hoping this last treatment has me on the mend and many of my side effects from the decease and or the treatments disappear. You all know I'm just dreaming LOL. I will be happy just to gain a few more years with my wife in my life. Right now I am using 200 mil every 12hrs of Hydroxychlorquine  for reducing my joint pain and 9 mil of Hydromoriphone controlled release twice a day and it has made my life for the most part with out my arthritic joint and muscle pain for 4 years. 5 years ago I gutted and refurbished my small peacetime house and built a small 8x24 addition. I have had a torn router cuff for about 25-30 years that flared up on me and will need orthoscopic surgery after I recover from treatment. I was scheduled  for surgery but it was canceled due to this treatment. I am so looking forward to getting my self on the mend and regaining some of my life back. I occasionally get gout flare ups and I think or blame it on post treatment sx . Like yesterdays flair up and I used some Naproxen, it greatly helped with the gout but I still feel my joint pain for some reason. Oh well time to take some more drugs.  



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Thanks for starting the thread!
I will be seeing a Rhuemetologist (Spelling?) at somepoint in the future (had to reschedule because of gas money)
They want to test me for psoratic arthritis. (I have Psoraisis) (UGH) I was diagnosed with plain ol Arthritis when I was 26. And that was a mild concern for my doc before I started treatment.
I have noticed after TX that my aches and pains seem to be much worse... it sux.

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Genotype 1A, Genotype (from parents) CC, Viral Load=7,514,000 (as of 12/6/11) Started Triple Therapy TX: 12/17/2011.UND @ 4-48 Wks Taken Off Incivek @ 6 wks due to Rash Response. Finished TX 11/17/12. SVR year 1



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My father is 81 years old. He never has joint or body pain
when he wakes up nor during the day.
I thought all my pain was from aging (54)
But doesn't seem the case.


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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!



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Thanks for this Malcolm,

http://en.wikipedia.org/wiki/Meloxicam

I will ask the Dr. for this, recently he gave me Tramadol, which I am afraid to take, siting hepatic failure as a side effectcry as well as addictioncry

Blessings, Iris

 



-- Edited by Iris Dragonfly on Sunday 8th of September 2013 10:11:19 PM

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Thanks for details Malcolm. Glad it's not RA! Any ideas what is the cause of your arthritis issues?

My hip, knee and ankle joints still ache and i have urge to pull em apart (stiffness). I do not take any NSAIDs tho, since i can manage pain. I had a light stiffness joints feel for years (HCV induced?), but post treatment it just got worse. Would like to blame usual suspect (interferon), but seems things are much more complex.

Hope you get back to normal and off NSAID meds (i bet Meloxicam ain't that great to take for a longer period)

best



 



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GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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Hi Malcolm, I`m so pleased the tests showed you don`t have RA or similar, and at least you`re getting some relief from your aches and pains, even if temporarily.  Let`s hope that they will ease up, or better still clear up altogether as time goes by and you get your full strength back.  You live an active lifestyle and that`s got to be better for your muscles and joints than sitting around all day!

My post tx experience has actually been quite the opposite.  After years of being in almost constant pain with aching muscles and joints (while being severely affected with M.E./ C.F.S.) going through tx and clearing the virus has made a significant difference and at last I`m virtually pain free.  I don`t want to crow about this when others are suffering, but I`d just like to point out to everyone that interferon tx doesn`t necessarily lead to these sort of problems, we are all different and how we respond post tx varies quite a lot.

Thanks for giving the test details and so much more helpful information, this is a very useful thread and I`m making it a `sticky`. 

Cheers, Jill



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(68 yo, lives in UK)

Was Gen 3a, 

24wks Peg/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Malcolm,

Thanks for starting this thread, I shall bookmark it for reference, as "pain and stiffness" are a constant companion for me, these days. Mostly in various parts of the back, mostly upper region. I've stopped any kind of weight training at the gym, just doing cardio on the elliptical. I'm going for a 3 day fishing trip out of San Diego next week, but when I get back I think I'll speak to my GP about some kind of pain relief. Tylenol just doesn't work for me, but I won't take ibuprofen unless my gastro doc approves it. However, I feel a bit sheepish about asking my gastroenterologist for permission to use ibuprofen, almost like asking him if I can start drinking alcohol and using intravenous street drugs.  gen068.gif

My primary care physican is big on prescribing SSRI & SNRI drugs for all sorts of conditions, unrelated to the original purpose that the FDA approved them for.    some might actually work , the Nortriptyline he prescribed for cramps in feet & later in toes did work nicely. 



__________________

"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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I, too am having much pain in my joints....
Wrist, ankle, elbow, hip and feet.
It's awful! My feet are in bad shape.
I have has to take my bracelet off as weight
Of it bothered my wrist.
I had even thought maybe Hep C is back.
After reading posts, I see this is common.
I will ask my doctor to do blood tests you
Had Malcolm.
My right knee bothered me going down stairs.
It has stopped lately. My right hip is still hurting.
It's great being off medicine.
I am glad there is medicine to take that's easy
On the liver.

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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!



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Hi Matt,

It's pretty common to blame Interferon for all our post-Rx muscle and joint aches and pains. That may be true.  After my 3 previous courses of interferon, I never had any problems, but I was younger then, and was not basicly housebound for 48 weeks.

The NSAIDs don't cure any conditions, just provide relief.  All of them can cause gastric problems and other Sx, and there are a range of drug interactions.  They should only be used with medical guidance. The newer NSAIDs are more effective, but should not be used for lengthy periods . Mobic and Naproxen are much more effective than Ibuprofen, and my doc and my chemist agree that Mobic has the least Sx. It is mostly used for pain and stiffness from Rheumatoid and Osteoarthtitis, but is also effective in non-specific disorders of joints, muscles and tendons. With summer coming over here, I hope that golf, sailing and fishing will strengthen my muscles and stretch the offending tendons and joint capsules. As I said, the pain and stiffness have gone, virtually overnight, but I don't want to rely on drugs for this. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm



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Glad you brought this up. I am about 9 weeks post tx and i have been getting some really weird pains. Like arthritis in my joints, which i never had before tx. I dismissed it to age also. But maybe i will see about a blood test too.



__________________

58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Hey Malcolm

Glad to hear you have found some relief from the joint and muscle pains.  (Hit a birdie for me when you Golf)

This NSAID or Non-steroidal anti-inflammatory drug, is it for some other application as well as post SOC treatment?

Malcolm do you think these joint and muscle issues were due to the cumulative amount of Interferon (3 Interferon go-arounds) or do most HCV patients that used Interferon typically have this issue on 24 or 48 weeks of treatment whether they have one treatment or multiples ?

Again thanks for the detailed info on the tests. We really have to appreciate the forums format of being able to access archived  information that gives important insight, and can answer questions on topics that may come up in the future for our members benefit.

The search engine feature is under utilize by some of our members because it can answer questions and give great insight into hundreds topics of interest.

Of course I realize their is nothing more stimulating than a good exciting thread to join in on but sometimes we need answers immediately and the search feature can really help.

Matt



-- Edited by Matt Chris on Saturday 7th of September 2013 09:22:55 PM

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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



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Hi all,

Since EOT, I developed some new joint and muscle pains, particularly in the knees, wrists and hands.  I dismissed it as being age related and due to my 48 weeks of inactivity.  As it didn't improve and I was overseas, I emailed my doc, who gave me a list of blood tests to have when I returned to Australia.  He also recommended a NSAID called Mobic, which I didn't get until 2 weeks ago.  I had been taking Nurofen with only slight relief.

Mobic is Meloxicam, one of the new generation NSAID's.  It has little effect on the liver and does not cause gastric irritation, and it lasts 24 hours. Usual dose is 15 mg/day.  It has caused a dramatic improvement to the extent that I can now work on my boat, and play golf without pain and swelling in the hands and wrists.  I only intend taking it for a month.  Hopefully my 'arthritis' will have settled down. That's only my experience, so I'm not trying to sell it!

The blood tests were reassuring in that I definitely don't have Rheumatoid arthritis or any other autoimmune problems. I had previously done the Rheumatoid Factor which was negative. The tests were:

CRP: C Reactive Protein, which is a non-specific measure of inflammation in the body.

antiCCP: AntiCyclic Citrullinated Peptide antibodies. This is very specific for Rheumatoid Arthritis.

ANA and ENA: AntiNuclear Antibody and Extractable Nuclear Antigen antibodies. Both are positive in any autoimmune disease, specifically from HCV or Tx.

ESR:  Non-specific test for inflammation, but always raised in Rheumatoid Arthritis.

Sorry to be longwinded and technical, but I have seen many posts where Members complained of post Rx aches and pains. These tests are a good way of seeing whether you have developed an autoimmune problem from Rx (including thyroid problems), or from HCV itself.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 74 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +4 years

Malcolm

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