Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> On Treatment -> UNDETECTED AFTER ONLY 6 DAYS ON SOVALDI AND OLYSIO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Post Info TOPIC: UNDETECTED AFTER ONLY 6 DAYS ON SOVALDI AND OLYSIO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Jeanno


Member

Status: Offline
Posts: 18
Date:
RE: UNDETECTED AFTER ONLY 6 DAYS ON SOVALDI AND OLYSIO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Permalink  
 

OMGosh!  I am so glad for you and this gives me so such hope. I am feeling mentally so much better. Can you tell me if you had increased upper right quadrant pain after you started your treatment?

I am so heartened by your progress. I am on day 7 and have my first labs on 10/15 and if they are anything like yours I will be elated.

Congrats Skewed.  What a blessing.  Keep being good to you.

God Bless and Namaste!!!

 

 

 



__________________

Walking in Faith, 58 yr old female with genotype 1 diagnosed 12/2006, infect. 1984 from blood transfusions, no previous treatments, no cirrhosis, recently developed lyphodema from chronic hcv inf. diag with CFIDS 1993

 
Dzdayscomin


Senior Member

Status: Offline
Posts: 471
Date:
Permalink  
 

skewedButNotBroken wrote:

I don't know why the liver panel test took so long to post to the Epic electronic medical record system, but I just checked and my liver panel results were there. So in addition to the virus being non-detected in 6 days my ALT and AST were well within the normal range for the first time in over 20+ years. However, my bilirubin direct test was 0.1 point over the normal range, but the total bilirubin was within a normal range. It seems to me that I remember reading that with the sovaldi/olysio treatment this is normal and that one should keep an eye on the bilirubin numbers. Is this correct?

One other note, it appears that my sleeping habits are back to normal and I'm not having any side effects whatsoever--knock on wood :)



-- Edited by skewedButNotBroken on Tuesday 16th of September 2014 02:01:34 PM



-- Edited by skewedButNotBroken on Tuesday 16th of September 2014 09:11:05 PM

 The sleeping thing is huge......I wish I had as good of luck with that...but I'm kind of a train wreck to hard to pin any problem on one thing.

Happy for you though!



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

I don't know why the liver panel test took so long to post to the Epic electronic medical record system, but I just checked and my liver panel results were there. So in addition to the virus being non-detected in 6 days my ALT and AST were well within the normal range for the first time in over 20+ years. However, my bilirubin direct test was 0.1 point over the normal range, but the total bilirubin was within a normal range. It seems to me that I remember reading that with the sovaldi/olysio treatment this is normal and that one should keep an eye on the bilirubin numbers. Is this correct?

One other note, it appears that my sleeping habits are back to normal and I'm not having any side effects whatsoever--knock on wood :)



-- Edited by skewedButNotBroken on Tuesday 16th of September 2014 02:01:34 PM



-- Edited by skewedButNotBroken on Tuesday 16th of September 2014 09:11:05 PM

__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Groupergetter


Guru

Status: Offline
Posts: 796
Date:
RE: UNDETECTED AFTER ONLY 6 DAYS ON SOVALDI AND OLYSIO!!!!!!!!!!!!!!!!!!
Permalink  
 

Hey skewed, sounds like things are looking up.  Really happy for you.  Being UND so early is a good sign.  Glad to hear you're having some increased energy and getting back to a more normal life.  I have the insomnia as well.  I hate to take sleeping meds.  Most leave me groggy in the morning and I have to get up and be alert for work.  I will take half an Ativan occasionally.  Would like to take Alleve but not so good for the liver.  I'm about a month away from finding out if my insurance will cover another round.  Hoping and praying it works out.  Be safe riding that rocket.



__________________

1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
Cinnamon Girl


Guru

Status: Offline
Posts: 5629
Date:
RE: UNDETECTED AFTER ONLY 6 DAYS ON SOVALDI AND OLYSIO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Permalink  
 

How fantastic, Skewed, congrats on such an excellent result!  Sounds like you`re feeling like a new man already..what a huge boost!! 

Onwards and upwards!!  smile



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

I'm feeling great! I feel like the clock has been rolled back 20 years. I slept pretty good last night with no sleeping aid.



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Gator Man


Senior Member

Status: Offline
Posts: 442
Date:
Permalink  
 

skewedButNotBroken wrote:
RonH wrote:

 Freaking awesome!!.


--It is freaking awesome! My only sx is insomnia. I don't have a problem going to sleep--I usually go to sleep between 10 and 11 pm, but since I started therapy, I wake up between 1:30am and 2:30 am and I can't go back to sleep. I've tried melatonin but that is not helping. I guess being sleepy everyday is a small price to pay considering the way I used to fe

Freaking awesome indeed! I have a similar sleep/insomnia schedule which hasn't changed in six months post tx. I take a 5 mg. timed release melatonin which helps a little. I do have a script for generic Ambien (zolpidem tartrate) and will halve a 5 mg. if I wake up before 2 am and have a tough day ahead. I never have any grogginess but still try to limit the frequency of use.



-- Edited by Gator Man on Monday 15th of September 2014 07:59:17 PM

__________________

Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.
Tig


Admin

Status: Offline
Posts: 9270
Date:
Permalink  
 

I've had tinnitus for years too. Some of it medication induced after being OD'd on Gentamycin antibiotics while in the service and I'm sure some as a result of gunfire exposure. But when I started the Victrelis while on Tx, it just exploded in volume. It seemed almost overnight I started noticing what sounded like rushing water. More than once I had to get out of bed and check the faucets to be sure nothing was overflowing or if I had left the sprinklers on. If memory serves me, it was Zlickster that told me to try Melatonin. I took 300 MCG once daily at bedtime. It took several weeks but I did notice a significant drop in the volume. I continued it through Tx but quit after SVR. But it's returning, so I'm going to go back on it and hope for the same results! I recommend it, providing it doesn't cause additional problems. I'm sure these drugs and various illnesses are responsible for many of the hearing complaints we all seem to share.

Tig

Tim: 300 mcg = .3 mg (point 3)



__________________

Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

Hep C FAQ   Lab Ref. Ranges  HCV Resistance

Signature Line Set Up/Abbreviations   Payment Assistance

 
Fireman Rob


Senior Member

Status: Offline
Posts: 334
Date:
Permalink  
 

Now that's truly impressive. I hope SVR follows! Congrats.

-Rob



__________________

Age 33, Male. GT-1 for ten years. Diagnosed in March, 2014.

Treated with Sovaldi/Olysio: SVR 24 on February 16, 2015!
hrsetrdr


Guru

Status: Offline
Posts: 940
Date:
Permalink  
 

Melatonin may help tinnitus? I'm interested, have had tinnitus for as long as I can recall. For a while during tx I had used Melatonin but discontinued because I could not determine the correct dose. The Melatonin I bought(iherb.com) came in 3mg caps; I would dump 1/3 to 1/2 out, not wanting to take too large a dose.

I'm going to revisit the use of Melatonin and see if I can get either better sleep, or better tinnitus control.



__________________

"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

Hi Tig,

I've had tinnitus for many years. I've always believed it was from the hep c. It is no better or worse now. I took 15 milligrams of melatonin -- the stuff makes me feel sort of weird. I don't think I'll take it again. I had a good day today. I wrote some html and javascript code, I took a ride on my 202 rwhp beast (My Kawasaki Ninja ZX-14R). I worked in the garage, etc.



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Tig


Admin

Status: Offline
Posts: 9270
Date:
Permalink  
 

Hi Testiva,

I'm glad to hear you slept through the night! It gives you something to smile about when you wake up and realize what you've accomplished! I'm curious about your use of Melatonin though. How much did you take, when did you take it and for how long? The first time I tried it it didn't do much for me either. But I tried again and after several weeks I started to notice a good improvement in both amount of sleep and the quality of it. I also noticed a huge improvement in the amount of tinnitus I was suffering with. I stopped talking it after SVR but the problems with sleep and tinnitus both are returning. So I'm probably going to start again and hope for a repeat performance! Good luck...

Tig



__________________

Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

Hep C FAQ   Lab Ref. Ranges  HCV Resistance

Signature Line Set Up/Abbreviations   Payment Assistance

 
hrsetrdr


Guru

Status: Offline
Posts: 940
Date:
Permalink  
 

Truly amazing Skewed, when I started tx I never thought that this would be feasible, for quite some time at least.

__________________

"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

I slept 7 hours last night without any sleeping aid! I truly feel like a new man now :)



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
TazKat


Senior Member

Status: Offline
Posts: 479
Date:
Permalink  
 

How awesome... That is a stress reliever for sure!!!! smile



__________________

TazKat Genotype 1A null responder x 3 riba & iterferon twice, relapsed from Incivek 2012 with only 12 weeks left to do. stage 4 mild cirrhosis 4/25/2014/ started sovaldi riba & interferon.. finished treatment 7/17/14  results 7/25  cleared..

 

 
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

RonH wrote:

 Freaking awesome!!.


--It is freaking awesome! My only sx is insomnia. I don't have a problem going to sleep--I usually go to sleep between 10 and 11 pm, but since I started therapy, I wake up between 1:30am and 2:30 am and I can't go back to sleep. I've tried melatonin but that is not helping. I guess being sleepy everyday is a small price to pay considering the way I used to feel.



-- Edited by skewedButNotBroken on Sunday 14th of September 2014 12:37:49 AM

__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
RonH


Veteran Member

Status: Offline
Posts: 73
Date:
Permalink  
 

Freaking awesome!!

 



__________________

Genotype 2, VL 10,000,000

Sovaldi 400milligram 1x daily Ribavirin 400 milligram 2x daily. Started treatment 8-19-14, UND 9-30-14 UND 11-12-14!
Dzdayscomin


Senior Member

Status: Offline
Posts: 471
Date:
Permalink  
 

That really answers a lot of questions that many of us had doing this tx and why we felt that euphoric feeling after just a few days.

Nobody was doing a VL test that soon and the fact you stepped up and paid for it to see is cool for all of us that did the tx, and those that still may do that tx. Thanks SBNB

Duane



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
Groupergetter


Guru

Status: Offline
Posts: 796
Date:
Permalink  
 

GREAT NEWS.  I took my first dose at 3:30 pm.  That night as I lay in bed I could positively feel the virus being killed.  Wish it would have lasted.  Hoping and praying you get SVR.  Be well.



__________________

1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
Isiscat2011


Guru

Status: Offline
Posts: 1724
Date:
Permalink  
 

Excellent news, skewed!  smile



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

A couple of days ago I asked Dr. Paul Martin's nurse (Nabiha Sanchez) to ask the doctor if he would order a viral load test for me because I feel so much better. She said that he probably would not order it because BCBS had authorized a 4 week viral load test and they would not pay for it. I told her that since my wife works at Lee Memorial Hospital in Fort Myers, FL that I get a discount for all services and that I would pay for the test myself. He ordered the test and early yesterday morning I had the test performed. Today at 4:00 pm Nabiha called me and said that I am undetected. I asked her 4 times, "are you sure?" She kept saying yes I'm sure. This is absolutely amazing to me. I thank the good Lord for this gift. I'm still in a state of shock.



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> On Treatment -> UNDETECTED AFTER ONLY 6 DAYS ON SOVALDI AND OLYSIO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.