Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Post Info TOPIC: Mavyret.2


Member

Status: Offline
Posts: 16
Date:
RE: Mavyret.2
Permalink  
 


Hey there, checking in here on Day 6 on Mavyret. I feel pretty good. Canuck, i did read NRA4ever's posts and was so happy to see he checked in to let us know that he continues to be undetected after 1 year, that leaves me feeling very hopeful... I have not had any side effects, except, right after i take it, i feel a little jittery, emotional and spacey for the 1st 30 minutes-1 hour. It's my 1st day back to work today since I started Mavyret. I work 2:30-11 PM. I'm thinking that I will be fine at work. I was so worried about being able to work on tx, because, of course, i have not shared with anyone at work that i have HCV, as I am sure many of you can relate to the stigma... Happy New Year to all of you!! There's a cure now after waiting many many years!! Yay for us!



__________________

62 y.o female HCV since 1977, (40 years). Genotype 1B, Dec 2017: ALT 53, AST 48, PCR 70,500. Fibroscan, very little scaring. Treatment naive. Mavyret: 8 weeks SOT 12/27/17, EOT 2/20/2018. EOT PCR Undetected!!! ALT 10 AST 17



Guru

Status: Offline
Posts: 2394
Date:
Permalink  
 

Hi mpls,

Can I suggest something like this for a signature line for you? Sig. lines just make it easier to recall important details at a glance, and helps in conversations. Sig. lines can always be changed and/or added to as you go along.

... Age, Sex, GT 1b, HCV aprox. 40 years, diagnosed (date). Pre-treatment labs: (Date) ALT/AST both aprox. <50, VL† _____ aprox. "low", (Date) fibroscan shows F score _____ aprox. "little scarring". TN. Mavyret 8 weeks - SOT Dec 27, 2017, EOT Feb ____, 2018 ...

If you have any trouble figuring out how to do a sig. line, see the link for it, below Tigs own sig line.

Good you confirmed your planned course of Mav is 8 weeks versus 12.

So, that is great that you have not felt anything bad from being on Mav so far. Do drink lots of water! What time of day did you decide to take your medication? Are you consuming it with some food?

How have you felt, how has your health been, all in all, in the past decades leading up to your now treatment?†

I do hope we can rustle up some other long-cured Mav-doer names for ya - Skimily has not posted back for a long time, and NRA4ever has subsequently, periodically returned to say he is still doing just great. If you managed to slog through bits of his thread, you will see with what GREAT trepidation he approached the drugs in his trial, only to be competely surprized that NOTHING bad happened, only good. Skimily and NRA4ever are 2 success stories.†smile†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 62 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Moderator

Status: Offline
Posts: 861
Date:
Permalink  
 

Hi MPLS, Your LFT?s are all low considering 40 years of the virus. And it also sounds like your liver is in good shape. 1b responds really well to treatment! Abbvie finished up the phase 3 trials on Mavyret in 2016 . I was offered a spot in that trial and was also offered a spot on Gileads Polaris trials, and I chose Gilead Polaris- and it gets really complicated from there on. I couldent beleave that I had two trial offers at the same time. TIG may post the links to the trials on Mavyret in this thread. 8 weeks wil go by so fast, your not going to beleave how fast it went by when you get to EOT. Stay in touch- RC



__________________

†M-61 (3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017) On my way to SVR. † †SVR-12.†3-13-18



Member

Status: Offline
Posts: 16
Date:
Permalink  
 

Good to hear from everybody. Thanks for the tips and links. I've been searching the web looking for anyone else who has started Mayvret. †Norwegian Waffle, it's nice to meet you. We can compare notes. I will be on Mavyret for 8 weeks, apparently my virus levels are low, and the fibroscan indicated very little to no scaring, my ALT and AST were both <50. I have had HCV for 40 years. †I work part time and have health insurance. I'm hoping I have no side effects so i can keep working. Since this medication is different than Harvoni, i have been looking for information on the people †(probably from the clinical trials) who have been cleared of HCV after a year after Mavyret treatment. Thank you all for your support.



__________________

62 y.o female HCV since 1977, (40 years). Genotype 1B, Dec 2017: ALT 53, AST 48, PCR 70,500. Fibroscan, very little scaring. Treatment naive. Mavyret: 8 weeks SOT 12/27/17, EOT 2/20/2018. EOT PCR Undetected!!! ALT 10 AST 17



Member

Status: Offline
Posts: 16
Date:
Permalink  
 

I had an ultrasound...i want to say they said it was a 3....or really good which was another reason they were not keen on epclusa. I just threw all my papers away (life changes) but they should be calling me to make sure all is well and I will jot the info. down and put it in my bio.†



-- Edited by NorwegianWaffle on Saturday 30th of December 2017 02:55:44 PM

__________________

†30 yo f, geno 3a, diagnosed 2007, AST 55, ALT 106, 5.8 million†

@4weeks Mavyret Not detected AST 17 ALT 12



Guru

Status: Offline
Posts: 2394
Date:
Permalink  
 

Hey NW!

Congrats on your start! First pill past the lips, and on to the cure! Don't be nervous. Drink lots of water. Nice you reply here where another (mpls) started her "On Treatment" thread. You too are officially "On Treatment" now!†smile Nice you and mpls will be able to compare notes! Both of your starts so close together!

I guess we will all find out from your 4 week blood draw whether you end up being on Mav for 8 weeks or 12 eh? Did you ever answer about where your liver fibrosis is at? Whether you ever had an abd. ultrasound, what your most recent blood "fibrotest" result was, or if you ever had a "fibroSCAN" to indicate your degree of fibrosis? Do you know your Fscore?†

This will be my new years toast to both you and mpls!†biggrin†C.

Image result for one gallon jugs of water



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 62 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Guru

Status: Offline
Posts: 2394
Date:
RE: Mavyret
Permalink  
 


Hey there mpls,

Welcome here. Nice to meet you. Glad you've got your Mavyret start underway!†biggrin†Yes, we have had others on Mav, and about to start, and/or are waiting to find out when they might be able to start.

Great Tig has directed you to another new member (Norwegian Waffle) who is about to start her Mav (she also started a thread with the same title as yours!)

If you put "Mavyret" in the search box†(above) you should be able to pull up various MAV related info and threads.

Quite a while ago we had two people on Mav trials, when Abby was still calling their Mav product "ABT493/530", they were "Skimily" and "NRA4ever", they were posting in this other long thread back then -††Abbvie ABT 493- ABT 530†.

There is also some Mav history here -†Abby's - Pan 8 week Glec/Pib†- the beginning of this thread spells out the evolution of Mav coming to market.

Is your length of treatment 12 weeks then? How have you and your liver been doing up to arriving at treatment?† Like Tig advised, drink lots of water! and fire away if you have any questions.†smile†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 62 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Member

Status: Offline
Posts: 16
Date:
Permalink  
 

Took my first dose about 30 minutes ago!



__________________

†30 yo f, geno 3a, diagnosed 2007, AST 55, ALT 106, 5.8 million†

@4weeks Mavyret Not detected AST 17 ALT 12

Tig


Admin

Status: Offline
Posts: 7950
Date:
Permalink  
 

Hello and welcome to the forum! Glad youíre here and really happy to hear you have started treatment. Youíre going to do great, this is one of the newest blockbusters available and it is very effective.†

We have some members either just starting or getting ready to start Mavyret. Iíll include a link to the other thread. >>HERE<<

Remember to drink at least a gallon of water everyday, WITHOUT FAIL! Your body will thank you for it. Itís a very important part of treatment with these new DAAís. They dehydrate you without even knowing it. If you have any questions, donít hesitate to ask. Others will be along soon to say hi. Good luck to you!†smile



__________________

Tig

61 yo GT1A - 5 Mil - A2/F3 - (1996) Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ

Signature Line Set Up/Abbreviations† †Payment Assistance



Member

Status: Offline
Posts: 16
Date:
Mavyret.2
Permalink  
 


I started Mavyret 3 days ago. I've had hep c for 40 years, treatment naive, Genotype 1b. †So far so good, not one side effect. Is there anyone else out there who is on it and/or completed it?



__________________

62 y.o female HCV since 1977, (40 years). Genotype 1B, Dec 2017: ALT 53, AST 48, PCR 70,500. Fibroscan, very little scaring. Treatment naive. Mavyret: 8 weeks SOT 12/27/17, EOT 2/20/2018. EOT PCR Undetected!!! ALT 10 AST 17

«First  <  1 2 | Page of 2  sorted by
 
Quick Reply

Please log in to post quick replies.

Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.