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Post Info TOPIC: non responding to triple tx.


Senior Member

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RE: non responding to triple tx.
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So sorry Tio,

May you respond to better drugs with less side effects!

Keep us posted.

Kate



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wilsondog


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Sorry to hear about that...on the plus side, there's a whole bunch of therapies on the horizon now...compared to 5 years ago. Your doctor should know about trials that you can sign up for.



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Diagnosed Geno 1a, 1992. Relapsed after riba-peg trmt in Aug 08. Oct 22 2011: Incivek 3rx @ 18 million VL.

Day 10: <15. --------------------->>>>>>12 OCT 2012: SVR!!! 



Guru

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So sorry you`ve had to stop tx Tio, you gave it your very best shot. hmm Take some time to rest and recover now, and remember there`ll be other opportunities coming your way at some point in the future.

Hope you`ll be staying around, you`re always a great support to people here. smile

Wishing you all the best, Jill xx



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Hi Tio,

We haven't spoken much but I wanted to add my feelings as well, as many have said you have inspired and encouraged many people with your kind words of support and we share your disapointmment. Take this time to heal your body and get back to your self again even though you didn't finish your tx, what you have done will have really helped your liver tremendously.

Take care and get ready for round 2.

Best Wishes,

Greg



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The mind is like a parachute it works best when it is open. "The Dalai Lama" My blog: http://greghcv.wordpress.com/
Genotype 1a, started tx 1st Feb 2011, for 48 wks. Week 24 PCR 26/07/11 Non-Responder
New TX start date 12th Sept 2016 Harvoni x24 weeks.  VL 7.4 Mil. Week 4 "Undetected"



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sorry to hear!no



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Geno 1 A Started Tx 8-3-11, Viral Load  21.2 Million,  4 Week Lead of Soc ,9-1-11 <43 On Soc alone started victrelis 9-3 ,8 week pcr vL und.Week 12 Vl Und, Did Week 24 PCR Results UND @ Week 24!!! 1-11-12,End Of Tx 2-15-2012 !!



Veteran Member

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Wow - sorry to hear that.



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Type 1B - Unknown for 30 years, diagnosed September 2011, started treatment February 2012

8 weeks Incivik - stopped early due to rash.

Continuing Pegasys and Ribavirin until January 2013 - 48 weeks

Undetectable from week 4 --> present



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Tio,
I'm so sad to hear this. Take care of yourself and keep us posted on what's new with you. Hugs!!!

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Genotype 1a, non responder to Peg/Riba in 2005. Started triple therapy 1-27-12 with Victrelis.  UNDETECTABLE as of 8wk labs (after 4 weeks of Victrelis) 4-3-12. UND at week 8, 12, 16 & 20 of tx. Completed triple therapy Oct 2012. relapsed 10/2012



Guru

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I'm sorry to read this, Tio.  You inspire so many here with your great big heart.  Better days are ahead for you; this is only a temporary set back.  



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.



Guru

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Hey Tio! so sorry it didn't work this time--but I do know there is new stuff being developed. Hang in there and hang around here!
Shep

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Diagnosed 1996 genotype 1b VL alot tx starting 12/23/11 Victrelis UND week 8!!! 28 weeks of tx

Completed tx 7/6/12--still UND!!!!



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Hey jim

 

So they took me off all treatment in week 8 after I went from 5000 to one million.  I have tried interferon 4 times and o for 4.  I am also stage 2 level 2 unchanged from ten years ago - I did a study with BMS7000 last year with interferon and ribravitrin - it didin't work...  let me know how yours goes!!!



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 



Guru

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Tio, man...I'm so sorry, you gave it a real good fight, hey...don't be a stranger anyway ok, we appreciate your input. and like Jim says...something else will be coming. Blessings, Iris



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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)



Guru

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Hey Tio,

Sorry you had to stop but it must mean there is something else coming for you. One doors closes another one opens. Be patient and get as healthy as you can. It took me a while to get back to normal, whatever that is...

Jim



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jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 



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Tio I am so sorry. Please never give up. You are such a good person. I hate this for you wish I could change this outcome.

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Senior Member

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So sorry Tio that it did not work. I hope you are OK. And you do get a break from treatment and new drugs will work for you once they come out. Just get some rest and recuperation. Let us knw how you are doing if yo feel like it. You are much appreciated here. Much love!!!



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Tio


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Disappointed.  lab results show I don't respond to tx.  (no 1/2 log drop in VL which means I don't respond to interferon. Dr. advised I stop. :(  but I will wait for the new nucleotide drugs in the pipeline, or get into a study.  I know several pharmacutical co. are developing new stand alone drugs for treatment.  At least I don't have to do any more tx for a while.



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