Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> General Discussion -> ten years from now
Post Info TOPIC: ten years from now
Phil G


Senior Member

Status: Offline
Posts: 303
Date:
RE: ten years from now
Permalink  
 

The same can be said for cancer treatment and survival rates, minimally invasive surgeries (orthoscopic), and other medical advances. Unfortunately, with better meds and proceedures, there is going to be higher costs and insurance headaches. I don't think Hep C will ever get the noteriety as other illnesses.



__________________

Geno 1A, VL 1.9 mm, SOT 12/2/11 - Pegintron/Ribavirin/Victrelis, UND since wk 8, EOT 6/15/12 (28 wks), SVR 11/30/12
JoAnneh


Guru

Status: Offline
Posts: 1077
Date:
Permalink  
 

Yes, this drugs are barbaric but they
Have a change to save us! I have cirrhosis
And thankful med is working. I can't wait to feel better.
I do hope future generations have easier time.
JoAnne

__________________

JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!
mallani


Guru

Status: Offline
Posts: 3398
Date:
Permalink  
 

Hi Mark, in 10 years we can look at the early protease inhibitors as 'the beginning of the end' for HCV. Incivek and Victrelis are remarkable advances, being the first DAA's. To be able to block an enzyme site on a virus that can't be cultured is a remarkable feat. It is just unfortunate that both drugs have bad Sx. This is because both drugs don't just block the HCV protease- they block other protease sites thoughout the body. The next generation protease inhibitors will be more selective in their action, and should be fairly free of Sx. Interferon has always had Sx as it is produced by the body and has a wide range of actions. To get rid of it, a combination of new DAA's will be needed to reduce the risk of RAV's. Riba may still be around in 10 years for certain groups of patients- although it's antiviral action is fairly weak ( and still not well understood).     In 10 years, the drugs will be consolidated into one or two pills/ day. The high pill burden we currently suffer could have been reduced eg the 4 Vict. caps could have been compacted into 1. The Rx time will also be compressed into 6, 12 or maybe 24 weeks.(or even less).

Looking back in 10 years time, patients will shake their heads in wonder at what we put up with. I can't wait 10 years, so I'm happy to be on these 'barbaric' drugs.

    



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Bills


Guru

Status: Offline
Posts: 648
Date:
Permalink  
 

I like what your saying
I guess this is like one of those necessary evils we have to deal with I'm at week 16 of this second round this time Inciveck I didn't do week 16 VL yet but I think I'm ok UND last one @ 12
If & When I clear SVR I don't want to see anymore Drs and hope I can hold my tongue about drug companies
Well Have a nice Thanksgiving
Bill S



__________________

Bills

Harvoni started 12-12-14 for 24 wks PrevTX Geno 1 stage 3 cirrhosis - non resp Int/ ribv. Started Trial  in Aug 2011 -July 2012 into Incivek relapsed  Feb 2013 Had 72 weeks on interferon & Riba.

marktrux


Senior Member

Status: Offline
Posts: 168
Date:
Permalink  
 

I was just wondering how members and the  medical community will look  back on the current SOC's. Will we look back on them as the lifesavers they appear to be or will we look back on them as some form of barbaric medieval torture that was rushed into production to satisfy the stockholders of Big Pharma? Personally I'm glad to have had the oppertunity to rid myself of the evil inside, though sometimes it dosen't feel like it.



__________________

KCCO

 

 
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> General Discussion -> ten years from now
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.