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Hep C Discussion Forum -> General Discussion -> Does your viral load go up, if you are a non-responder to treatment???
Post Info TOPIC: Does your viral load go up, if you are a non-responder to treatment???
mallani


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RE: Does your viral load go up, if you are a non-responder to treatment???
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Hi Nancy, we've discussed all this before, most recently on JoAnne's thread 'Did my doctor make a mistake on treatment duration?' in this section. If you become undetected while on Rx, the cycle of inflammation and liver damage stops. If you rebound or relapse, the cycle starts again. There is little correlation with VL. The longer you are Undet., the longer your liver has a chance to start to heal itself.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
JoAnneh


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According to Malcomb and others on forum YES the liver gets a break by time to repair some of the damage. Viral loads fluctuate but normally go up if you still have Hep C

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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!
52baddog


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Need to know if your liver gets a rest from the virus attack, while you are on treatment. If you don't respond to treatment, then does your viral load go up??



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Geno type 1b, F1 vl 640,000 enrolled in Gilead's sofosbuvir/ledipasvir -week 1 66, week 2 <25
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