Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> On Treatment -> ? about non-interferon treatment in trials
Post Info TOPIC: ? about non-interferon treatment in trials
Biggyb


Guru

Status: Offline
Posts: 820
Date:
RE: ? about non-interferon treatment in trials
Permalink  
 

Hi Marilyn thanks, that petition has gone around on here before but it's always good to bring it up again for the new people.




__________________

58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~
Marilyn


Member

Status: Offline
Posts: 7
Date:
Permalink  
 

Hi,

I am new here and I found this site to help all hep c patients.  I belong to an organization that is trying to get the new human treatment to treat Hep c released now.  Here is the site to sign the petition www.hepc-cured.com    The story is this Bristol-Myers Squibbs has a drug called datclatasvir and Gilead Science has it's GS-7977 now called sofosbuvir.  When only these 2 drugs are used they get 100% cure in 12 weeks.  No Interferon and no Ribavirin!!!!!! It works on all genotypes.  Gilead is refusing to work with BMS because it wants to corner the market for themself and want to try and make a generic and use it with Ribavirin the results are poor and harmful to the patients. BMS is willing to work with Gilead.  I have hep c and found this information out this Dec. because my blood work is bad.  I started looking around at treatments again and ran across this treatment information and the head organizer for the release of this new treatment for all hep c patients now before more of us die.  There is no place for corporate greed when it comes to such a deadly disease.  Please help.  Sign the petition, spread the word, tell everyone, we have flyers, poster, wristbands that we can get to you and you can duplicate and display where ever you can.  I put a 8" by 11" poster in dry cleaners, Chinese restaurants, pet stores, pizza shops, laudramates, bowling lanes, supermarket bill boards, etc.  Please email me back and I will get the poster to you.  maleisz@aol.com

Best

 



__________________
Marilyn A. Leisz
DJ


Senior Member

Status: Offline
Posts: 306
Date:
Permalink  
 

And couldn't you go with the usual treatment for the genotype 3 and if it didn't work, then see when this becomes available if it would be an option? I do hope something new that works well for genotype 3 comes out, but the odds are good for our genotype and it is worth a try to get rid of the virus.



__________________

Genotype 3.  Treatment started on 1/11/2013 with Ribavirin and Pegatron.  Week 4 UND.  Week 12 UND.  Ended treatment on 6/28/2013.  Six months post treatment 12/04/2013 SVR.
mallani


Guru

Status: Offline
Posts: 3398
Date:
Permalink  
 

Hi Jeri,

You're probably referring to the first Phase 3 trial released by Gilead. It refers to a trial of Geno 2's and 3's treated with sofosbuvir and ribavirin.

The results for Geno 2 were quite good, but the SVR rates for Geno 3's was disappointing at 61%. There will be other Phase 3 trials coming. The treatment duration was 12 weeks, compared to the usual 24 weeks of SOC. However, the dose of Ribavirin was higher and weight-related.

Would you rather have a 12 week regime of sofosbuvir with a high dose of Riba, for an SVR chance of 61%, or would you rather have 24 weeks of Rx using Peg. and a lower dose of Riba, with an SVR rate of >80%. Maybe a better drug combo. will become available. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
DJ


Senior Member

Status: Offline
Posts: 306
Date:
Permalink  
 

Is it for Genotype 3?  That is also my genotype, and it seems like everything coming out is for genotype 1 only.  So that is something to consider.

I do hope they come out with something that will work with genotype 3 if regular treatments do not work.  I am starting treatment on Friday, and of course hoping it works and I am done, but I would sure feel better if I knew something new and better was coming out soon for genotype 3 to try just in case this treatment doesn't work.



__________________

Genotype 3.  Treatment started on 1/11/2013 with Ribavirin and Pegatron.  Week 4 UND.  Week 12 UND.  Ended treatment on 6/28/2013.  Six months post treatment 12/04/2013 SVR.
GodsGrl


Senior Member

Status: Offline
Posts: 113
Date:
Permalink  
 

I was looking online last night and say that in 2014 a new non interferon treatment will be available here in the USA, been in trials with good results. Way less or no side effects. I'm stage one chirrosis  I'm considering waiting, was scheduled to start treatment this next week. Thoughts????



__________________

Geno Type 3A  Double TX 1-30-13 2 1/2 week labs VL >43 Lab error on 12 week VL no result

 
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> On Treatment -> ? about non-interferon treatment in trials
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.