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Post Info TOPIC: Week 24 - UND


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RE: Week 24 - UND
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Wow - 3.5 weeks to go!  You must be longing for that day?  How wonderful that you've navigated your treatment in such a positive way and I'm so sure that you've been an inspiration to so many people here, along with you being a fountain of knowledge as well.

Thanks for the link, I had not heard of this.  My husband is classified cirrhotic (I think). It's very hard to get a solid response to that question from any specialist.  They say there are so many variables, that it is impossible to be sure unless a biopsy is done again.  My husband had a biopsy initially years ago when he was first diagnosed, and has had a couple of fibroscans since, the latest being in June last year. 

We are glad to be over the half way mark, although I see my husband tiring more.  He still works full time (fortunately a desk job), but it's a tough mental job which I think can sometimes be more draining than actually being more active.  He has a really good attitude though and is a very determined man, so I am thankful for that.



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My husband had genotype 1a, 46yo, started triple therapy (peg/rib/vic) 23rd July 2012, VL prior to treatment 14 million, UNDET 12, 24 weeks, EOT 24th June 2013, EOT +1.5 weeks UNDET, EOT +12 weeks & EOT +27 weeks UNDET; SVR January 2014



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Hi Caroline,

I've got 3.5 weeks to go.

RGT is Response Guided Therapy. It's where treatment length is tailored to VL results. It uses the VL at 8 weeks, 12 weeks and 24 weeks. I've posted a link . Normally 48 weeks are only done for cirrhotics or those who have a late Undet, response. Cheers.

 

http://www.natap.org/2011/EASL/EASL_92.htm



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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I just posted a reply but cannot yet see the post, which is why I'm adding another post rather than editing.

I forgot to tell you Malcolm that my husband is doing 48 weeks.  How many weeks have you got left - you must be nearly finished?



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My husband had genotype 1a, 46yo, started triple therapy (peg/rib/vic) 23rd July 2012, VL prior to treatment 14 million, UNDET 12, 24 weeks, EOT 24th June 2013, EOT +1.5 weeks UNDET, EOT +12 weeks & EOT +27 weeks UNDET; SVR January 2014



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Thanks everyone for your wonderful encouragement.

Malcolm, what is RGT?



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My husband had genotype 1a, 46yo, started triple therapy (peg/rib/vic) 23rd July 2012, VL prior to treatment 14 million, UNDET 12, 24 weeks, EOT 24th June 2013, EOT +1.5 weeks UNDET, EOT +12 weeks & EOT +27 weeks UNDET; SVR January 2014



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Excellent news, Caroline, congrats to your hubby!  thumbsup.gif  So good to hear this, what a boost for you both!  ~ Jill



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Hi Caroline,

Great result. How many weeks is hubby doing? I know you didn't get a 4 or 8 week VL, but is he eligible for RGT? Cheers



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Whoot-Whoot Caroline...Awesome ... I think we're on a roll .. thanks for sharing..all the best to you and your hubby MJ



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Do not go where the path may lead, go instead where there is no path and leave a trail.Ralph Waldo Emerson

1a - VL 22 million  F2- IL28B- CT / Inck-Riba- Peg triple therapy 9/15/12 UND 4/8/14  8 wks BT ..3/1/2013 done! 3wks Post UND



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Congratz. Awesome, that's a string of us, 3 or 4 who had UND at week 24 in the past week and a half.

At this rate we'll get 100% cure rates soon enough.



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58 yrs, cirrhotic, Genotype 1b 48 weeks Victrelis triple, SOT 7/13/12 victrelis started week 5. Starting VL 4,000,000  Wk 8 33 copies  Wk 24 UND, EOT UND 6 months post Tx DET. The battle goes on.



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Fantastic, there is no news that is better. Hope you both keep getting great results.



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Genotype 1a, IL 28 = CT  Interferon and riba 48 wks in 99, Daily Peg and Riba 18 months in 2007, Started Incivek, Peg, Riba 6/21/12. 4th stage cirrhosis. Last Dart will be May 23 2013.



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Hubby got the VL results last week for Week 24 - Undetected. Very happy to go into the New Year with a great result.



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My husband had genotype 1a, 46yo, started triple therapy (peg/rib/vic) 23rd July 2012, VL prior to treatment 14 million, UNDET 12, 24 weeks, EOT 24th June 2013, EOT +1.5 weeks UNDET, EOT +12 weeks & EOT +27 weeks UNDET; SVR January 2014

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