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Post Info TOPIC: is grapefruit and juice compatible with 3x therapy Vict


Guru

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RE: is grapefruit and juice compatible with 3x therapy Vict
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Hi Bill,

Although grapefruit juice is supposed to be good for the liver, there are some problems with the protease inhibitors. It's hard to make sense of the waffle, but one of the grapefruit compounds is hard to metabolise when the protease site is blocked.

Metformin is OK. Some Type 2 diabetics here are taking it with triple Rx, but check with your doc.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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I have been told by the Mayo Clinic, where I'm participating in the BMS QUAD Clinical Trial, that grapefruit juice and products containing grapefruit as well as Seville oranges should not be consumed while taking protease inhibitors and/or NS5A protein inhibitors. Joe

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DJ


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I don't know either, but I have heard that grapefruit juice is not good to take with a lot of medicines, so it may be safer to not use it. You should ask your doctor about it to know for sure, or call the drug companies.

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Genotype 3.  Treatment started on 1/11/2013 with Ribavirin and Pegatron.  Week 4 UND.  Week 12 UND.  Ended treatment on 6/28/2013.  Six months post treatment 12/04/2013 SVR.



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I have no idea, hopefully someone knows.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Never got a straight answere on this when taking meds is grapefruit juice or eating a grapefruit ok with medications.  seen news where some medications have a bad time with grapefruit.  Will have to ask also about Meforin to Diabetic Association

Bill and Family



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Geno type 1  rib and peg September 2012 , 5 weeks tripple and viral down to < 15 und april Aug 25 finished stay at peg 3 rib and eprex + blood transfussion finished treatment Aug 25 2013

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