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Post Info TOPIC: Boceprevir vs Teleprevir


Guru

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RE: Boceprevir vs Teleprevir
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What i have read victrelis(boceprevir) is way more tolerable. I am on my 38th week. Still  Teleprevir is only 12 weeks. Same SVr rates.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



Guru

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Hi Bob,

This has been discussed many times before. Do a Search and just type in 'Victrelis'. I have done 2 posts on Incivek vs Victrelis, in General Discussion, on 24 July 2012, and 17 Feb 2013. In general, Victrelis is regarded as the 'kinder' drug, although the anaemia may be more severe.  Good luck.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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I have been doing triple therapy for 5+ weeks and have had VL go to near undetectable for three straight weeks (non-linear range so no number).  That is greater than a four log drop.  But with this, my side effects have been intolerable.  Fatigue to the point of not being able to get out of bed, not helped by more rest.  So after discussion we have stopped ribavirin and teleprevir.  No ifn planned until next friday.  After talking to my doc, we discussed substituting boceprevir for teleprevir.  Obviously very few people have done both.  Wondering if anyone has insights into the differences between the two drugs vis a vis side effects.

Thanks :)



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