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Post Info TOPIC: constant WBC drops treatment halt/nupogena?


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RE: constant WBC drops treatment halt/nupogena?
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blood stats (i guess Malcolm will enjoy em?)

i am still amazed by the jump i have made in 7 days, just with my-doc-not-beliving-in-it supplement (ImmunoMAX AHCC)...next goal, bring WBC and neutrophiles to week 2 of tx levels!

best



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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will you do FibroScan too?

FibroTest could be option (it's just 50EUR for mathematical automatic formula, smart french money leeches), ask your doc?

i am always for all possible noninvasive tests ;-D

 



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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I think you will make it buddy, everything is inching up, so take a deep breath! :D

I have an appointment with the liver goddess next week. She expects to see no damage or she'll eat her shoes, This could get interesting! :D

 



__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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Lisa, yeah! i was reallly really anxious last nite...as i said, i never would ever dream i could fight to stay on interferon ;-D but seems i will make it...if it were 5th month of tx, i would be more relaxed, but 3rd month sounded really like damn, i am gonna loose at least 30% of svr change if i lower interferon dosage or skip few doses ;/

hope this supplements ain't giving me placebo fx ! ;-D (which lasts 2 weeks or so?)

when are your biopsy results due?

cheers!



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




Guru

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That is great news, Keep at it, it will be 6 months before you know it! :D



__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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popcorn, liver( Veal has less Cholesterol than pork) and green tea are almost my daily diet.
Great infromation! thanks Zlikster.
 
Zlikster wrote:

to be honest, i only had one day liver (veal liver only! everything else is no no)

re diet tips for WBC i have received:

- popcorn (no microwave, no flavor)
- beet juice
- liver (veal)
- green tea

supplements:

- folic acid
- Echinacea
- immunomax AHCC

all consumed daily


 



__________________

 1b, start triple treatment(incivek) on Feb 5, 2013.  UND@ 4,12,24 wks. EOT Aug 6, 2013



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to be honest, i only had one day liver (veal liver only! everything else is no no)

re diet tips for WBC i have received:

- popcorn (no microwave, no flavor)
- beet juice
- liver (veal)
- green tea

supplements:

- folic acid
- Echinacea
- immunomax AHCC

all consumed daily



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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Hello Zlikster. great news, your WBC is up!.  I see your MD doctor also recommended to eat more liver as nutrition.
I am very happy for this infromaion because in my daily diet, I usually eat pork liver. Maybe it is helpful to me. But Pork liver have very high Cholesterol. My Cholesterol level is normal.
 
 
Zlikster wrote:

after only a week of supplements, my WBC is bit up! This is first raise in WBC since start of the therapy

only 2 things i have added to my supplements: folacin tablet x 1, 3 x 2 Immunomax AHCC and nutrition wise i have included lots of popcorn. Popcorn and AHCC is recommendation from friend who went with interferon therapy for lymphnode cancer and had WBC problem too (advice from his oncologist). Folacin and Echinacea (which i plan to add from today) is advice from one MD doctor with experience in hematology, he also recommended to eat more liver as nutrition. I only took one B12 im shot (i was supposed to do it daily, but it was really painfull). I am not sure did these supplements/nutrition did this and what exactly raised it, but i suspect AHCC was the main thing. My doc on other hand was really skeptical round AHCC, instead to be happy if it is the thing that influenced raise of my WBC (well i guess docs can be stubborn about unconfirmed supplements too!), I am too skeptical tho about it's antiviral marketing, but maybe it can raise WBC a bit just nuff so i do not get reduced dose of interferon FIGHT IS ON!

WBC              2.1 > 3.5!!!
lymphocytes 1.3 > 2.0
neutrophiles 0.7 > 1.1!!!

RBC              3.76 > 4.10!!!
HGB              112 > 127!
       

in 2 weeks it's next blood check, i will continue to use AHCC (3x2), (from today) Echinacea 3x1, Folic acid x 1, 2 x 500 B12 (which did nothing previously!)


hope this information helps someone?

cheers!


 



__________________

 1b, start triple treatment(incivek) on Feb 5, 2013.  UND@ 4,12,24 wks. EOT Aug 6, 2013



Guru

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after only a week of supplements, my WBC is bit up! This is first raise in WBC since start of the therapy

only 2 things i have added to my supplements: folacin tablet x 1, 3 x 2 Immunomax AHCC and nutrition wise i have included lots of popcorn. Popcorn and AHCC is recommendation from friend who went with interferon therapy for lymphnode cancer and had WBC problem too (advice from his oncologist). Folacin and Echinacea (which i plan to add from today) is advice from one MD doctor with experience in hematology, he also recommended to eat more liver as nutrition. I only took one B12 im shot (i was supposed to do it daily, but it was really painfull). I am not sure did these supplements/nutrition did this and what exactly raised it, but i suspect AHCC was the main thing. My doc on other hand was really skeptical round AHCC, instead to be happy if it is the thing that influenced raise of my WBC (well i guess docs can be stubborn about unconfirmed supplements too!), I am too skeptical tho about it's antiviral marketing, but maybe it can raise WBC a bit just nuff so i do not get reduced dose of interferon FIGHT IS ON!

WBC              2.1 > 3.5!!!
lymphocytes 1.3 > 2.0
neutrophiles 0.7 > 1.1!!!

RBC              3.76 > 4.10!!!
HGB              112 > 127!
       

in 2 weeks it's next blood check, i will continue to use AHCC (3x2), (from today) Echinacea 3x1, Folic acid x 1, 2 x 500 B12 (which did nothing previously!)


hope this information helps someone?

cheers!



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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here are my blood tests sorted in timeline...(sorry some labels are in bosnian)

i talked with a doctor (MD) who had publications regarding treating blood problems with mild radioactive water (he helped my gradnma a lot in just 2 weeks, tho with RBC/Hg levels)...he said nutrition wise to eat more liver? add folic acid and echinacea? i am not sure about his advice...anyone had any experince with nutritional/supplements and WBC raise?

thanks!



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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thanks Bouba, but i presume u live in a country with normal health care ;D

i will prolly have to buy Nupogen injection on my own seems so...my doc also doesn't wants to lower dosage of interferon, but i am not sure how to help her. Opt in for Vit B12 injections (daily), try to get Nupogena? i think i will try to get advice from some good immunologist first, i just don't like timeframe/deadline (lower dosage of interferon from this Sat and 2-3 weeks max to bring back levels or else)...

thanks!

__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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I did Neupogen for the last 10 weeks of treatment after my neutrophils level dropped sub 0.75.

My doc did not want to compromise on Interferon dose.

It was a weekly injection, no big deal, but it had an immediate effect, increasing leucocits/neutrohils 10 times.

good luck! 



__________________

58 yo male, HCV since 1981. Gen 1B (IL28B, CT). Diagnosed 1999,  VL before tx 100'000. Biopsy A2, F3 fibrosis. Naive, SOT (with Incivek) Oct 26, 2012. UND @ week 4, 12, 18, 24, UND 12 and 24 weeks post-RX



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my granlucytes are at 0.7, WBC 2.1...tomorrow i am doing blood test again for proper neutrophil count (last one was 0.9)...doc said it's time to lower interferon dosage, maybe from 120mg to 100mg. I got 2-3 weeks max to rebounce WBC otherwise they might halt therapy completly. She said Nupogena is a last resort, but i have to pass a lot of blood checks and comission before it and she is not that keen on using it. Other option is daily Vit B12 injections (since obviously B12 in pill form ain't doing job) ;/

RBC (3.76) and Hb (112) are doing fine on other hand

i am bit anxious now, shall i try some more supplements before resorting to B12 injections or Nupogena? Doc said i can try whatever OTC meds i think might help and if i want i can go to immunologists for consultations...i don't have much time, i would like to go thru this therapy fully, i am half way there ;(

PCR results are now late almost a week...

this waiting game sucks...




__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!


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