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Post Info TOPIC: Newbie here, 2nd dose of Interferon and I'm already tired of popping pills all day. Any advice?


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RE: Newbie here, 2nd dose of Interferon and I'm already tired of popping pills all day. Any advice?
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Thanks soooo much everyone for all the advice. The past couple days I've felt almost "normal", with the exception of the oh-so-lovely anal discomfort from the Incivek. I've actually been unusually hungry, so it hasn't been as hard to down the fat. Of course, it's time for shot #3 tomorrow, so I'll be back to feeling icky again. Gotta love how that works.

I had called my doctors office a couple days ago to vent my frustration with nausea, and I was basically told I just gotta tough it out. She could prescribe Zofran, however I'm without insurance, and it would cost me nearly $100, so I'll pass on that. I was also told that as long as I'm not vomiting after every dose of Incivek, I'm good. And *knock on wood* so far I haven't had any more vomiting spells. 

I've considered using cannabis to cope with the side effects, however my boyfriend and I live together and he is a bit of a prude when it comes to that kind of stuff, even though I explained to him I wanted to use it to help ease the side effects, not to feel stoned. He still didn't budge on his opinion and he so kindly told me if I did, he would show me the door. Little does he know that after my first shot of Interferon, while I was in the floor crying, I called up a friend after he went to work and told her I felt like I was dying, and to bring over some "stuff" because i was so desperate. It helped me long enough so I could fall asleep. But being as my bf is so against it, it's not worth the risk of having to constantly sneak-n-smoke. 



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Amanda

25 years old. Genotype 1a, diagnosed in 2008. Started triple therapy May 17th, 2013 - Incivek, Ribavirin, and Interferon.



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Hi Amanda,

If I told you how the shots effected me you'd just be mad. It was the day after the shot or the next day, or sometimes the next...

Have you tried eating something after you take your pills or while you take them? I used to eat something fatty before and after-during taking the pills. I used to forget them, take them later, wish I could forget them... I used to take them and try to forget them. Maybe if you spaced them one and then one 30 mins of so later. You know it says every 8 hours but you have between 7 to 9 hours to take them. I never took them exactly on time. But I made it though them with UND's



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GT 1a Started triple tx with Incivek, Pegasys, and Riba 2-6-2013. UND at 4,6,12,23,& 24 wks EOT 7-26-2013. Probably had Hep C for 20-30 years. Don't really know when I got it.



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When I logged on here for the first time, gosh I was sick. You've already gotten great advice from the veterans. My nausea was pretty bad. I used every trick in the book, and just had to survive the weeks that it was the worst during Incivik.

Sounds like you're staying hydrated. Watch for nutrition. If you can get a protein shake in a flavor you enjoy, that will help you keep your strength up.

This will pass and be a distant memory some day. Seems like some are hit harder by it than others. Hang tight. xo Karen:)



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Diag 8-10. 1st VL 600,000. Gen 1a. Grade 4 Stage 4 cirrhosis w/ Esophogeal varices level 2. Viral load 1,750,000 7/12/10. Triple Therapy w/ Telaprevir began 7-15-11


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Hi Amanda,

i had similar experience for first shot (administred round 13h, round 19h worst fever in my life ever), round 5th shot i got used to and moved administering it to Fri (then Sat) night round 18-20h, so i force myself to sleep rite before first sx arrive and try to have deep sleep and oversleep most of the next day.

what helped me re interferon sx:

headache - lavander oil as scent, shortterm headache relief
nausea - ginger+lemon/lime+honey homemade drink and plain or with probiotics yogurt (it felt like icecream to me)
bath - sometimes it help, sometimes it made it worse

eat well days before shot. First few shots i couldn't eat properly for 1-2 days after shot...

i am not taking any painkillers or other meds except vitamin supplements...i did inhaled vaporised cannabis few times, just to induce munchies (helps in that area) since i have lost a lot of weight.






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GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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Hi Amanda

 

Im relatively new on here too and empathise entirely how you are feeling. Im seven weeks in and stll hate giving myself the injection. Remember it will get better as time progresses.The important thing for me is that if Im feeling ill, then the drugs are doing their job. It is horrible, but Id rather this than have to keep looking over my shoulder for the rest of my life wondering when or if this bloody virus is going to strike me down. Keep the faith and hang in there. Everyone is rooting for you. And listen to the vets and experts by experience on here. You wont go far wrong if you do

 



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Amanda, I was thinking about how to give you the best support I could about your sides, and then saw Lee's post. Don't know if you saw it, but here are some insights he shared which I think apply to all our experiences.

 

Anyways, that's enough about me. If there is anyone new reading my post and anxious about starting triple therapy, my advice is:

  • try not to read too much into side effects, the more think about them,  the more they will manifest themselves;
  • don't get hung up about compare yourselves to others, we are different and will experience different side effects;
  • set reminders to take your pills, I am on 20 tablets a day, so I have reminders in my calendar on my iphone and download a drug reminder app with handy sound effects. I am pretty strict on adherence and would recommend sticking to a good regime with your tablets. Even with all these reminders, I  have been about 2-4 hours late with a couple of tablets so far;
  • keep a log of your treatment and cross out the weeks you have gone through, highlighting weeks off the calendar, just shows visually how far you've come! I am half way through my treatment and when I first started, 48 weeks seemed like a lifetime;
  • try and maintain a balanced diet and exercise if you can - I find weights in the gym and light cardio really helps mentally, yes I can't lift the weights I once did and I have lost muscle mass, but I have adapted to lighter weights and leaner muscle;
  • it's okay to pig out when you feel down after interferon, if eating fatty unhealthy foods, makes you feel better, do it;
  • try and live as normal a lifestyle as you did before, yes you will probably be fatigued a far bityawn.gif, but try and do things that make you happy, exercise, go out for food, buy new clothes, go to the movies/, socialise with friends, read, listen to music, walk the dog or whatever you feel like doing, etc.
  • its okay to feel like ****, for a long while I was angry that I felt awful and tired all the time. After a while I just went with it and I the times I feel like **** are getting less and less, I don't know if that anything to do with my subconscious or not, but things have got easier.


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Genotype 1a, IL 28 = CT  Interferon and riba 48 wks in 99, Daily Peg and Riba 18 months in 2007, Started Incivek, Peg, Riba 6/21/12. 4th stage cirrhosis. Last Dart will be May 23 2013.



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Welcome Amanda, my side effects have been different from the peg all through treatment so far. Gotta just deal with it any way you can. This forum has been a blessing. Keep fighting onward...Good Luck



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Hi Amanda, welcome from me too!  Well done for starting treatment, it`s never an easy decision to make but from what you wrote in another of your posts it sounds like this will be the perfect time for you to get on with it.

Yes, I had pretty similar experience with my first shot.  I was expecting to have `flu like` symptoms but not as severe as they were!  But the rest of my shots weren`t anywhere near that bad.  A lot of people find their first shot is the worse, although it`s different for everyone really and some people get away with very light side effects.

The nausea is very unpleasant but with any luck it will ease off as your body adjusts to the med a bit more.  I didn`t do the triple therapy, just peg and ribavirin, but I had quite a lot of nausea during the first few weeks.  For me sipping fizzy drinks were very helpful, especially ginger ale, and I kept a packet of plain biscuits handy to nibble on, but it`s best to eat and drink whatever you feel like as our tastes tend to change when on treatment.  Things should certainly get easier for you once you`ve finished the incivek.

`Panadol` is the same as `paracetamol` or `tylenol` by the way, and it`s widely available over the counter.

Feel free to ask any questions, someone will always be along to try and help or give you a few words of encouragement.

Best of luck!  ~ Jill

 

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Thank you for the input! :) I've always got my water bottle by my side, I've been adding in the ginger ale and coke, so I think I'm staying hydrated enough. And the added flavor is helping with the overall icky taste in my mouth. I've noticed the nausea really kicks in after I've taken Incivek....maybe an hour or two after I have a dose. I'm going to call my doctor tomorrow and mention it, as I have thrown up a couple times not long after having a dose and Im worried about not absorbing it. Today I took my Incivek with pork fried rice, and so far that's been the only thing I've eaten that hasn't made me cringe....so I think it may be my new favorite fatty food lol. I had been drinking a couple glasses of whole milk and eating a few mini candy bars with the medicine, but now that I've throw up milk....I don't want to see any for a long time :(

And is panadol something I can get over the counter? I haven't heard of it before -- but definitely willing to give it a try! This nauseousness is something unlike I've ever experienced....almost like a motion sickness feeling, or the overall queasy feeling you have when you're pregnant (don't worry - I'm definitely not at the moment! lol that was the first thing my mom thought of when I talked with her today).

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Amanda

25 years old. Genotype 1a, diagnosed in 2008. Started triple therapy May 17th, 2013 - Incivek, Ribavirin, and Interferon.



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I drank ginger tea, green tea and FLAT ginger ale. Saltine crackers seemed to help also. But the general disgust of food never went away until the Invicek was complete. It really sucked to have to force feed myself every 8 hours. The 20+ grams of fat also help with nausea and other issues. If it continues, you may want to see your Dr about a Rx, the vomiting could affect the dose absorption. Good luck and keep fighting!



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KCCO

 

 



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Hi Amanda,

People have different reactions to the Peg injection. I had no problems at all and did 48 weeks. Try taking a panadol 2 hours before the injection, and if you do it on Friday night, wait until you're ready for bed.

Fizzy drinks like coke and ginger-ale made me feel nauseous and I stopped all the carbonated drinks. Make sure you drink enough water ( at least 2 litres a day) to keep yourself hydrated. Your food tastes may change so try to eat bland foods.  At least you've only got 12 weeks of Incivek- try 48 weeks of Victrelis!  Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Howdy all, I'm new here. I just started treatment May 17th (I'm a member of the friday night darts club too) and I will never forget how awful I felt after that first shot. A few hours after leaving the doctors office, I started to feel tired and achey....and then what started out as flu-like aches turned into a feeling I hope I never have to experience again. It literally felt like my bones were on fire, and like someone was taking a match to the bottom of my spine. No matter how I sat, laid, walked, etc....the pain was unreal. Then the low grade fever came on. Fun stuff lol. Once I was finally able to fall asleep (after a few benadryl and my "usual" night time meds), I woke up the next day feeling pretty darn good. All was well until a couple days before my last shot, I've been feeling nauseous and had a few spells of vomiting. My dr prescribed phenergan, but so far that isn't doing much good. Friday night I tried my best to prepare for my 2nd shot, and it wasn't NEARLY as bad as the first poopy shot. I had some minor aches and a little bit of nausea, but that was it. Now 3 days later, I would give ANYTHING to shake this nauseous feeling and heartburn. My dr said the first shot would be the worst, but I was wondering if anyone else had such a drastic difference from their first to second shot? Also, any advice for dealing with the nausea? I dread everytime my alarm goes off for me to take the Incivek....the thought and smell of food makes me want to hurl. And I'm already hating the color purple because of those darn pills lol. I've had about 4 different spells of vomiting the past 2 weeks, but I honestly thing I'd rather throw up than just FEEL like I'm going to throw up. I've been drinking ginger ale, coke, taking phenergan (but that seems to be a joke right now)...I can't seem to get a bit of relief :( I'm sorry for sounding whiney, but just venting in this paragraph has given me a little relief. I greatly appreciate any input! :)



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Amanda

25 years old. Genotype 1a, diagnosed in 2008. Started triple therapy May 17th, 2013 - Incivek, Ribavirin, and Interferon.

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