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Post Info TOPIC: Is Jaundice a Side affect of Triple Treatment


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RE: Is Jaundice a Side affect of Triple Treatment
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Hi Roughrider and Tig,

As far as Victrelis and Incivek go except for treatment length and sx the only reason I can see that they might prescribe one instead of the other is Vitrelis seems to work better than Incivek with people who were prior null responders or have relapsed from treatment before. I have read some information on Incivek's fact sheets that said that.

Either way both have a lot better SVR rates than the old dual Peg & Riba treatments.

Good luck with your treatment and keep us informed. Lots of good folks here.



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GT 1a Started triple tx with Incivek, Pegasys, and Riba 2-6-2013. UND at 4,6,12,23,& 24 wks EOT 7-26-2013. Probably had Hep C for 20-30 years. Don't really know when I got it.



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Tig56 wrote:

I'm one here that is on triple therapy too, but it seems almost unusual because I'm on Victrelis instead of Incivek. Do you ever see a higher number of patients here on Vic versus Incivek? 


 Hey Tig, I been on this site about a year now and the Incivek people always seem to outnumber us on Vict. They say SVR results are identical.

I am glad i chose Vict. I think alot of us older folks are getting Vict mainly because of lighter SX. But, and this is a big but, we have to stay on it for 44 weeks, at least most of us do. ~Cheers~



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Hey Tig56,

Oddly enough, the Group of Drs I'm seeing did not ever mention Victrelis as an option.  I did hear about it but it was when the pharmacy was sending my first mailorder. 

I feel ok, but the severe burning is present and rash has already arrived.  It is hard to wear shoes on day 4 of treatment!

I feel full all the time, maybe the fat just lies around inside.  Eating all the time will be hard for me, I found Jif Peanut Butter Chocolate Silk, this is 19 gram individuals and tastes good to me for now.

I have lost 4 lbs eating 20 grams of fat 3 times a day somehow, might be the increase in water for me.  Water isn't my favorite but I do it like the medicine.  One of my meds for BP could be affected by this treatment so I have to keep an eye on that and so far ok.

I feel good and I'm looking forward to the work week to help keep my mind busy. I'll stop back by, have a good week everyone and hang in there!

RR55  

 

 



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Genotype 1A
Tig


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I'm one here that is on triple therapy too, but it seems almost unusual because I'm on Victrelis instead of Incivek. Do you ever see a higher number of patients here on Vic versus Incivek?  I believe after all of the comments here and elsewhere that I might be fortunate to be on it instead, idk. I know that everyone is different but at the same time I've noticed more and more people having miserable side effects from the Incivek. There's always the fact that I'll be on Victrelis far longer than the Incivek but it seems to really have some good tradeoffs. I asked my doctor last week about the decision to use Vic instead. I was unhappy because the Incivek also has it's pluses. The SVR rate in many reports has it's success rate 10-15% higher overall. But the rates of stopping treatment with Incivek is higher because of side effects. That was my doctor's response to my question, it's a hard drug to tolerate for many people and he personally had good success rates with the Victrelis for a variety of reasons, tolerance being a big one. At least I now have a better understanding of why I'm taking one versus the other. I want to mention that the Victrelis does indeed have it's own unpleasant side effects, it's not pleasant any way you look at it. I don't know what future effects will be because of the Vic, I'm only 10 days into it. Time will tell. I pray hard that the treatment for this disease is greatly improved in the near future and some of the studies that people here are currently on show great promise and it sounds like the side effects are being reduced by these new meds. We can hope for something simple in the future and do whatever we can now to tolerate the effects of the treatments currently available. The help from people here make the road to success much easier to follow! 



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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rough rider,

     consider yourself very lucky to only have the rash on your feet! on day 3 i had it on  over 2/3rds of my body. think of treatment  as an adventure in coping/handling side effects.

     finally there are others on this forum who got the rash early on as well. hang in...

sandy,ucbgal



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Hi Cinnamon Girl and Mallani,

 

No particular reason other than I was self consious during last treatment.  I'm glad to hear the details and experience you bring.  I feel ok, I have a rash starting on my feet already, I am just a few days in on medicines..  I was able to work full time during my first 48 week treatment.  I am anxous this time adding the new medicine and am wondering how fast the side affects come.  I know eveyone is different though.  Thanks for the respones



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Hi Roughrider,

Jaundice is not a side effect of Rx. As Jill said, why are you asking? Whether you can continue to work varies from person to person, and is usually related to the degree of anaemia. Good luck.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Hi Roughrider, welcome!  I see you`ve just started the triple tx with incivek, how are you feeling today?  Well done for taking your first shot!

Is there a reason why you`re asking about jaundice, do you have any signs of it yourself, or is it a general question?  It`s certainly not something you`d expect to see while on tx. 

Many people are able to continue working throughout their tx, although it does vary from person to person quite a lot, and depends on how you react to the medicines. 

All the best of luck this time around...Jill



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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I am concerned about the treatment causing Jaundice.  Does any one have experience with this one?  I so hope to continue some level of working and social activity during treatment. 



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