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Hep C Discussion Forum -> General Discussion -> First interview for trial
Post Info TOPIC: First interview for trial
Liamc


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RE: First interview for trial
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Hi all,
Thanks for your replies, I asked the doctor to write down the name of the trial so I am just coping that. Sorry have not got any more info than that.

__________________

GT3a Age 61. Clinical trial sovaldi/riba 24 weeks. finished trial 17th April 2015 undetected. EOT+4 weeks undetected.24th July 2015 "SVR"

24 week SVR!!
mallani


Guru

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Hi Liam,

Sorry, can't find your Trial. Have a read of this article on Geno 3 Rx options. It specifically mentions that non-nucleoside NS-5B inhibitors are pretty useless in Geno 3 ( and actually mentions ABT-333).

As we won't see Sovaldi, let alone the other new DAA's until 2015 at the earliest, it may be worth biting the bullet and trying 24 weeks of Peg/Riba. The SVR odds are 60-80%, which is not bad.

http://www.hepatitiscnewdrugresearch.com/hcv-genotype-3-ndash-the-new-treatment-challenge.html



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Matt Chris


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Hey Liam

I have looked for that trial but can not find it, but you should check the drug name again as the 2nd generation Abbvie NS5A is called ABT-530

Abbvie typically will use three or four drugs in their therapy but some of the arms within the study may have less. It can be confusing the first time you hear the names and numbers so I would ask for some clarification on the possible arms that you could be randomized to.

matt 



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
Cinnamon Girl


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Hi Liam, good to hear your news.  I haven`t found anything about this on the clinical trials website so it probably hasn`t been listed yet. Good to know that Abbvie are including genotype 3`s anyway. 

Best of luck!  And do keep us posted when you have some more information. 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Liamc


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Hi, went for an interview today for an Abbvie trial coming up, its called Abt 333/Abt267 2nd generation n55a inhibitor plus rbv has any one any knowledge of this treatment?

thanks

 



__________________

GT3a Age 61. Clinical trial sovaldi/riba 24 weeks. finished trial 17th April 2015 undetected. EOT+4 weeks undetected.24th July 2015 "SVR"

24 week SVR!!
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