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Hep C Discussion Forum -> General Discussion -> End of Treatment Strategy & Recommendations
Post Info TOPIC: End of Treatment Strategy & Recommendations
Gator Man


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RE: End of Treatment Strategy & Recommendations
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I actually considered the prospect of re-infection after vigorous flossing resulted in a minor gum bleed. This was shortly after 4 weeks of Tx and being UND for the first time. I did change my toothbrush and razor, but thought I was being a little paranoid. I will know more after my one month post EOT lab check on Wednesday.

Even if the risk is small, it certainly is an easy item to address during the course of Tx, even if you change these items daily.

Thanks for the information Matt, although regret that you are having to still deal with it. Longer Tx and eliminating contaminated personal hygiene items appear to be in order. Take care.



__________________

Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.
Kellie


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After becoming UND during tx I got new toothbrushes, razors. manicuring tools etc. I even went as far as throwing out lipstick, makeup brushes, eye liner pencils, everything that came into contact with any surfaces of my body. even body brushes and pumice stones went in the trash.

I think I read a post here last year about it and it made sense to me.

thank you Matt for bringing this up

 



__________________

HCV 1A 1980. Dual tx 2003 -UND at wk 11-discontinued due to severe depression

Started Triple 4/16/13 for 24 weeks

UND wk 4,6,8,12,17 & 24

E.O.T. 9/29/13

EOT + 12 weeks=SVR, and EOT +26 weeks=Cured!
Tig


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Hello J,

Remember, if you need a quick reference guide here on the forum, don't forget to use the search function. It's located at the top center of each page. Here is the forum page we have set up on them. Our member Mallani was responsible for this excellent guide.

Tx = treatment

Tig

http://hepcfriends.activeboard.com/t51085702/forum-abbreviations/



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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HR


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Hey Matt

Funny that you mention the reinfected part. The Gilead trial I was on did not say anything about changing your hygiene items either. This time I may change my razor and toothbrush daily.

Also I was sorry I couldn't meet you for lunch the other day but it was nice talking with you. We are going to kick this viruses ass this time.

Take care



__________________

ION-3 Trial- Sofosbuvir/Ledipasvir 12 weeks.. UND 4 weeks, relapsed 12 week EOT. 

3-4 on Ischank scale

 

Retreat ION-3 Trial- Sofosbuvir /Ledipasvir 24 weeks

GT-1 (1-31-14) Week 1 VL 62 -Week 4,8,12,16,20 UND EOT 7-18-14
Milliganus


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Wow!  Never even thought about this.   Thanks for posting.



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Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND
Omnamahshivaya


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I'm on day 3 and just tossed my toothbrush but I'm wondering if I should toss it every three days since I have no idea when the virus will all be cleared? Or is it just best to clear it when they tell me I'm UD? Btw - sorry but what is tx?

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OMJ - started treatment April 25, 2014

Prior to treatment VL 14 million. Liver Levels Abnormal but under 70.

Sovaldi/Olysio

VL: SOT = 14 million.    SOT +2 weeks = 28

AST/ALT: Normal

Week # 7 = UND
jimbob


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Hi Matt.
I was never informed of that as well (reinfecting oneself). It should be something that is discussed before every tx. Didn't even think about it until reading it here. So I disinfected all those items or changed them.

Jimbob

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jimbob: 64 y/o, GT 1A, F1-F2, diagnosed 1996. Since 1970. SOT 3.5 mil VL on 3/10/14 with Sov/Rib/Peg for 12 weeks. Tx naive. UND @ week 4,8,12. EOT 6/2/14.
Tig


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Hi Matt,

This is a very important topic and one that everybody needs to pay attention to. We have discussed this in months past and it's a good idea to bump the subject up every so often. I've taken to the routine of cleaning the hard surfaces in the house and soaking items like nail clippers in a bleach solution. There are a number of items that can be purchased that have a bleach component to them. You can also mix your own home sanitizer with household bleach and water.

Tig

 

 Here's another one of our threads that got a lot of attention:

Hep C Friends Thread

 



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Matt Chris


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Hello All

I am bringing this thread up now because I finally was informed via email from Abbvie / Turquoise II Trial doctor that my relapse was not caused from Rav's / Virus mutations. This is significant because I was UND at treatments end and for 2 or 3 weeks after (proved by blood tests) but on week 4 post EOT a small amount of virus was detected again it being the normal wild virus type.  There could be only two possible reasons why this could happen.

(A) A very small amount of the virus was still in my liver / Hepatocytes and my immune system could not control and vanquish and I required longer duration of treatment.

(B) I Re-Infected myself with a personal hygiene item ( nail clippers, tooth brush, etc.)

It has been established by Yale University article that the Hep-C virus can remain infectious for up to six weeks on surfaces at room temperature. Link to article -http://blog.aids.gov/2014/01/scientists-discover-hepatitis-c-virus-can-remain-infectious-outside-of-the-body-for-up-to-6-weeks.html

Unfortunately I never was made aware of this possibility by my trial nurse or doctor and was not aware of the it being talked about on our forum. So its critical that all members have a strategy or plan to either disinfect or discard personal hygiene items that could cause re-Infection. The other strategy I would recommend is keeping your immune system in top shape when you come off treatment.

Please read this link / thread from our forum regarding this topic its very enlightening     

http://hepcfriends.activeboard.com/t44673475/change-your-toothbrush-and-razors/

matt      



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
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