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Hep C Discussion Forum -> On Treatment -> Ribavirin & Sovaldi Side Effects
Post Info TOPIC: Ribavirin & Sovaldi Side Effects
mallani


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RE: Ribavirin & Sovaldi Side Effects
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Guys,

Don't be too keen to drop Riba. Sovaldi is useless by itself. Normal dose for an average male is 1,200mg in 2 divided doses. I know treatment sucks but why take a chance. Just my 2cents.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
longld


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another agreeing with Tig - I am on only 400mg of riba a day - seems like yours could be reduced.  Why are you on only 16 weeks, I thought std treatment for Gen 3 was 24 weeks? - what I am on.



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62 Yrs Old, CHC Geno 3, Cirrhosis, Kidney Transplant (13 yrs), On Sovaldi/Riba Treatment (24 week) since Feb 01,2014

Viral Load 7M on 1/8/2014,  UND at EOT 7/18/2014
Omnamahshivaya


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My doc didn't put me on Ribavarin because he could tell I was already a stressed out mamma! It's probably the Ribavarin. Hang in there. I agree with Tig that you should ask to take less or no ribavarin -- that it's making you irritable and unable to cope well. Lots of light to you. And me. And all of us.



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OMJ - started treatment April 25, 2014

Prior to treatment VL 14 million. Liver Levels Abnormal but under 70.

Sovaldi/Olysio

VL: SOT = 14 million.    SOT +2 weeks = 28

AST/ALT: Normal

Week # 7 = UND
OldenSlow


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Isiscat2011 wrote:

Wow, I hadn't realized this is your last week OldenSlow.   And, you are on the long (16 week) ride; taking the scenic route.  

Well done.   smile

 

 Scenic, indeed.  Sometimes you've just gotta laugh...  wink

https://www.youtube.com/watch?v=X1q3zwYx_R0



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66 y/o male - Geno 1b - F4 cirrhotic dx 2001 - 16 wk treatment w/ Sovaldi/Olysio/Riba - Und @ EOT+24 SVR

 
Isiscat2011


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Wow, I hadn't realized this is your last week OldenSlow.   And, you are on the long (16 week) ride; taking the scenic route.  

Well done.   smile

 



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Groupergetter


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Got a bunch-o short timers here, sounds mighty fine.  aww   Almost there Wayne, congrats.  Hang tough Robert, you're getting close, gotta make it to the finish line. 



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1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
OldenSlow


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Hey, RC..  16th week here and I feel your pain. The fourth month has been more difficult for whatever reason, at least mentally. The brain still works, though it has a nasty habit of disengaging itself wherever and whenever it pleases, kind of like a slipping transmission. Also too easily annoyed by people and noise and avoid both to the best of my ability. Spend a lot of time plugged into music, stay as busy as I can and try not to screw too many things up (mixed results on that one). Have found myself making uncharacteristic mistakes doing the simplest things. Duhh....

Good thing is we know it's the drugs and we know it's going to get better. It will be but a memory in fairly short order for all of us. You're almost there, my friend. Just keep taking those pills and I'll see you on the other side. ;)

wayne



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66 y/o male - Geno 1b - F4 cirrhotic dx 2001 - 16 wk treatment w/ Sovaldi/Olysio/Riba - Und @ EOT+24 SVR

 
jimbob


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Hi Robert.
Believe me, I can identity with many of your symtoms, especially the restlessness I am on my 10th week. I've tried to avoid home projects as I too have little patience. Somehow I have avoided the Riba rage (knock on wood). Only 3 more weeks to go Robert, you can make. As everyone has stated, avoiding certain situations help.
Good luck.

jimbob

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jimbob: 64 y/o, GT 1A, F1-F2, diagnosed 1996. Since 1970. SOT 3.5 mil VL on 3/10/14 with Sov/Rib/Peg for 12 weeks. Tx naive. UND @ week 4,8,12. EOT 6/2/14.
Huey


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Hi,., we are the same age, have the same genotype and on the same meds except for the sleep aid you take and the Hyoscyamine I take.

 I feel like that off and on , I have no problem sleeping in fact that is all i won't to do is sleep.  the talking too loud thing has been going on as long as i can remember.

 I think I have had this since i was 12 so it might be from the virus.  I am taking my Tx for 24 weeks, I don't understand why yours is only 16 but to your question, I have all those side effect and most of them i had before I was on treatment so i think the virus is the cause and as you get rid of it this should go away,  lets keep our fingers crossed.



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  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
Tig


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Hi Robert,

Have you discussed this latest trouble with your doctor? In the last couple of weeks for example? If not, it might be worth the price of a call. Are you still on the full dose of 1200 mg? You might be a candidate to reduce it some. It might help but with only 3 weeks to go, it might take that long for you to notice a dose reduction difference. Like the others have mentioned, this is definitely Riba related. I also noticed the problem of getting my words and sentences mixed up. We all experienced the irritability and rage. Avoid the situations as best as possible and if you're still working, and can take the rest of your treatment off, I'd recommend it. Hang in there bud, you're almost home...

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Isiscat2011


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Yes, just about everybody who has been on riba has experienced some or all of what you are describing, and it does pass.   Try to avoid stressful situations (and stress inducing people) to the extent you can.  Keep your surroundings calm and Zen like.  Only 3 weeks left.  

Btw, I've never heard about the changes in facial expression and wild eyes (kind of an Incredible Hulk thing going on, huh?) but I suppose that is pretty common too when people become very agitated.  

You aren't turning green, right? biggrin  It's not easy being green.



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
mallani


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Hi Robert,

Just Ribavirin doing its stuff. Just realize this and try to cope. After 13 weeks of 1,200mg of the stuff, it's not unusual. It'll soon be over and you'll be back to normal when the Riba leaves your system. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
robertsamx


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Im on 400 mg sovaldi and 1200 mg ribavirin, and 10 mg ambien to sleep.  Im  13 weeks into my 16 week treatment, and i always feel like im racing ,my mind gets ahead of my mouth, I say things in the wrong order sometimes. I will go from feeling what i call nornal to angry very fast, I think im talking normal and my wife says im hollering. Also my speech slures sometimes more in the morning and sometimes in afternoon. My facial expression changes when i get angry or overly excited, and my eyes get wild but then they change back to normall in a few hours, my puples get small when im angry or excited but then will go back to ok?I dont like being around people or noise.I have no patients. Im making mistakes on home projects that i normally do easy,I get pissed off really easy.  It seems the last week or two its been whorse.  Has anyone else experinced this?  Im just always mad.  Please will you all give me some imput??    RC



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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
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