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Hep C Discussion Forum -> On Treatment -> Solvadi/Ribavarin Side Effects
Post Info TOPIC: Solvadi/Ribavarin Side Effects
Huey


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RE: Solvadi/Ribavarin Side Effects
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I agree Barnacle , The side effect can be prety bad but I am able to work although I am on a lite duty , With me the biggest issue is Hypoglycemia right now.



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  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
Barnacle


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TazKat wrote:

I will be sooo glad when I get there. they had me off riba for 6 days. but putting me back on tomorrow. ugh.. I can do this I can do this...click my two red shoes together like Dorothy.. lol 7 shots left.. Taz

 Here ya go Dorothy



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57yo male gen 1a since '70s. Fib F3-4 VL >2M Tx started 5 Apr 14 Sov/Oly/Rib

wk 4 UND wk 8 UND, wk 12 EOT UND...keep em coming 24wks UND = SVR!
Barnacle


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I am on sovaldi/olysio/riba and other than the sun sensitivity from oly the riba Sx are minor. Slight rash on wrists and arms treating with topical cortisone and some minor mood swings. I am not a raging kind of person so riba annoyance is more how I roll.
I let my Dr guide me when to start Tx and it was a race for when new drugs (turns out it was sovaldi he was waiting for) would show up before my liver became too damaged. Turns out it was a close race but but I can see the finish line and I already feel better than I have in years even while on Tx
There may be some even better stuff coming out real soon if you cn wait but don't risk your health waiting too long. The new meds are pretty tolerable

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57yo male gen 1a since '70s. Fib F3-4 VL >2M Tx started 5 Apr 14 Sov/Oly/Rib

wk 4 UND wk 8 UND, wk 12 EOT UND...keep em coming 24wks UND = SVR!
TazKat


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I will be sooo glad when I get there. they had me off riba for 6 days. but putting me back on tomorrow. ugh.. I can do this I can do this...click my two red shoes together like Dorothy.. lol 7 shots left.. Taz



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TazKat Genotype 1A null responder x 3 riba & iterferon twice, relapsed from Incivek 2012 with only 12 weeks left to do. stage 4 mild cirrhosis 4/25/2014/ started sovaldi riba & interferon.. finished treatment 7/17/14  results 7/25  cleared..

 

 
Roxie


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OldenSlow wrote:

That being said... I empty out my last riba bottle tomorrow at 4 pm. My current plans are to take the empty bottle out back, put it on a rock and beat it to death with a sledgehammer. It will serve no earthly purpose other than making me feel really, really good.

wayne

 Wayne, I can so relate!!! Congratulations on emptying that last bottle.  On to SVR!

 Anna, I just finished 12 weeks of ribavirin. By the 8th week  I really wished I had waited for a non interferon / ribavirin option. If you have the option to wait, that's what I would do, knowing what I know now that I didn't know then. 

 

Roxie

 



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GT 1a / VL 6.5 million / age 64 / prior tx 1996 interferon

2/14/14 began Peg/Inf, Ribavin, Sovaldi for 12 weeks 

finished treatment 5/8/14  undetectable @ 4 wks, EOT & 12 wks
Isiscat2011


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OldenSlow wrote:

That being said... I empty out my last riba bottle tomorrow at 4 pm. My current plans are to take the empty bottle out back, put it on a rock and beat it to death with a sledgehammer. It will serve no earthly purpose other than making me feel really, really good.

 

          __________________________________________________________________________________________________________

 

Hahaha....... GO FOR IT!    This is a beautiful thing.  I am very happy for you and I just feel certain you will reach SVR! smile

 



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Tig


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Hey Wayne,

Buddy, I'm thrilled that you're done today! It's after midnight here, so I can say today!! Sounds pretty darn good doesn't it? I'm really happy for you and it'll take a day or three for it to sink in but it will and the thrill is wonderful to grasp. However, I want you to do me one favor. When you take that empty bottle out back and put the sledgehammer to it, be sure you wear some safety glasses!!! I'd hate to see that nasty little bottle get one last lick in, ha, ha!! Congrats my friend, it's going to get better and better, just wait and see

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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mallani


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Hi annabanana,

As already said, side effects of Riba vary enormously. Anaemia and fatigue are common, with the Riba rage and Riba rash pretty common. Current treatment for Geno 3 is for 24 weeks and Riba is part of the mix. We're waiting for the Trials to see how the new drugs shape up. Maybe Sovaldi/Ledipasvir for 12 weeks will be enough, without the Riba. Having said that, I was on the full dose of Riba for 48 weeks, and am still here. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
OldenSlow


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annabanana wrote:

The nurse practitioner told me the side effects (rash, mood swings, foggy brain etc) are from the Interferon not Ribavarin.  Based on what I have read on many of your posts...she is possibly sugar coating the Ribavarin. She said the biggest side effect they see from Ribavarin in anemia...any input? 

The most common "clinical" side effect, perhaps. Methinks there's a good chance your NP has never taken ribavirin. ;)  Isiscat has summed it up nicely. Everyone's experience will differ to some degree from everyone else's. Life circumstance, physical/mental condition, disposition, the other meds in the protocol... all will play a part. Not all side effects are easily quantifiable. And I don't want to scare you off, either. It's eminently doable, but may require a few adjustments along the way.

That being said... I empty out my last riba bottle tomorrow at 4 pm. My current plans are to take the empty bottle out back, put it on a rock and beat it to death with a sledgehammer. It will serve no earthly purpose other than making me feel really, really good.

wayne



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66 y/o male - Geno 1b - F4 cirrhotic dx 2001 - 16 wk treatment w/ Sovaldi/Olysio/Riba - Und @ EOT+24 SVR

 
Isiscat2011


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Hi Anna:

Some people have a fairly smooth time of it on Ribavirin; others have a horrible time.  It is difficult to appreciate just how horrible something can be until you experience it.  Many people have posted about their experiences and if you search "riba" or maybe "riba and side effects" here you will come up with countless posts.  We can get you the labeling info re: side effects but that will probably just scare the crap out of you.

Unfortunately, there is simply no way to tell how your body and brain chemistry will react to it.  

6 months vs 3 months-- that's an easy one for me.  

You may be able to avoid it all together as the new drugs come out and you have time, right?   



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
annabanana


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Hi Everyone,

I appreciate all the info that has been provided...I called my Dr's office today to discuss the pros/cons of starting treatment now or waiting.  The nurse practitioner told me the side effects (rash, mood swings, foggy brain etc) are from the Interferon not Ribavarin.  Based on what I have read on many of your posts...she is possibly sugar coating the Ribavarin. She said the biggest side effect they see from Ribavarin in anemia...any input? 

She said we don't know what the treatment protocol will be once the other drugs are approved so they could very well have Ribavarin in the mix (which I realize is accurate, but only 12 weeks not 24 weeks for GT3).

Still weighing the pros and cons and would love to hear more from GT3 who are being treated and how things are going.



-- Edited by annabanana on Friday 16th of May 2014 02:28:35 AM

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GT3A            DX 2002              VL 400,000           AST/ALT normal         Started Sol/RIBA June 9 2014 for 24 weeks
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