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Post Info TOPIC: Merck MK-5172 / Mk-8742 clinical trial
Tig


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Merck MK-5172 / Mk-8742 clinical trial
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Hey Jude,

I'd like to welcome you to the forum too! I considered it a very fortunate day when I came across this forum and continue to feel that way. There are many kind and knowledgeable people here, just waiting to share some help or a kind word. Please feel free to ask any questions that come to mind. I'd like to point out our "Search" function at the top center of each page. It's full of great information and if I can ever be of assistance, please feel free to leave a question anywhere on the forum or privately. I'm glad you have a friendly clinical care group, they really can make the difference between an easy trial or not. I look forward to hearing more of your progress as you move forward. Good luck!

Tig



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Tig

63 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

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Senior Member

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RE: Accepted into Merck MK-5172 / Mk-8742 clinical trial
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Congrats Jude.

Do you mind me asking where your trial is located?  I've been trying to get on this one also.



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Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND



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Hi Jude, welcome to our Clinical Trial Participants area, good to see you here!

This is an excellent drug combo and you should do very well.  You`re bound to be feeling a bit apprehensive before starting, that`s perfectly natural, and I`m glad you found us.  You can count on friendly support here and we look forward to following your progress.

Wishing you all the best of luck!  smile

(By the way, if you like you could write your details in your `signature` so that they appear underneath all your posts...just select `signature` in your user details profile info.) 



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Jill 

(70 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



Senior Member

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RE: New here, preparing for participation in clinical trial (Merck)
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That's great Jude !!  From what I have read during my research you have a great chance of achieving a cure.



__________________

57 Yr old, Diagnosed 1994 Geno 1a. 1995: Interferon 12 weeks.  1998: Int/Rib 10 weeks.  2014: VL 106,000. Peg Int, Ribavirin, Victrelis 48 weeks (commenced June 2014). UND after Peg/Int lead in week 4. Still UND at week 8, 24, EOT. SVR 12.



Guru

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Good luck with your upcoming clinical trial, Jude.  Hopefully you will have a smooth ride and achieve SVR.   Please keep us posted on how you are doing and don't be shy about asking questions.  Lots of good people and information here and many have done clinical trials with excellent results.  :)



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.



Guru

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Hello Jude

Welcome to the forum you have found a good place with caring members that can provide great insight on your journey during your trial.

Jude are you on the 12 week arm and are they adding Ribavirin with the other two drugs?

We have had another member (Suziq) that was successful with the same treatment. I was on Abbvies Turquoise II trial last year so I know how they can be, hopfully some other person/member will be on the same trial as you which will make it very interesting for you. Merck has had good results from that combo so far hopefully you also will.

matt



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



Guru

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Hi Jude,

Welcome to the Forum. You are lucky to get on the Merck Trial, as they are outstanding drugs and you should do well. Keep us informed. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



Newbie

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Merck MK-5172 / Mk-8742 clinical trial
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Comment removed at member`s request. 



-- Edited by Cinnamon Girl on Monday 29th of December 2014 11:23:23 PM

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Hep C diagnosed 2007.   VL 7Mil . Genotype 1A.  Treatment naive.  Grade of  Inflammatory activity per 2014 biopsy:  A1   Stage/Degree of Fibrosis F0 



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Comment deleted at member`s request. 



-- Edited by Cinnamon Girl on Monday 29th of December 2014 11:21:01 PM



__________________

Hep C diagnosed 2007.   VL 7Mil . Genotype 1A.  Treatment naive.  Grade of  Inflammatory activity per 2014 biopsy:  A1   Stage/Degree of Fibrosis F0 

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