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Hep C Discussion Forum -> Post Treatment -> Treatment Outcome Thread: SVR or Relapse
Post Info TOPIC: Treatment Outcome Thread: SVR or Relapse
Huey


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RE: Treatment Outcome Thread: SVR or Relapse
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  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
Isiscat2011


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Congrats to recent SVRers, TazKat and Audrey.  Well done.    



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
TazKat


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Congrats to the SVR's.. wow. science has come a long way!! so happy

 



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TazKat Genotype 1A null responder x 3 riba & iterferon twice, relapsed from Incivek 2012 with only 12 weeks left to do. stage 4 mild cirrhosis 4/25/2014/ started sovaldi riba & interferon.. finished treatment 7/17/14  results 7/25  cleared..

 

 
Dzdayscomin


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Audreyanna wrote:

just got 12 weeks post tx results:  SVR!!!!!!

55 year old female

treatment 12 weeks Sovaldi/Olysio

genotype 1a

compensated cirrhosis

 

previous nonresponder to interferon/RIBA in 1998 and pegulated IFN/RIBA 2010

 

I still am having a hard time believing it! Thank you God!

 So very happy for you.......may your life be filled with sunshine and warm breezes!

God Bless.

Duane



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53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
skewedButNotBroken


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Congratulations Audrey! The Lord has blessed you!



-- Edited by skewedButNotBroken on Saturday 25th of October 2014 07:29:35 PM

__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Audreyanna


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just got 12 weeks post tx results:  SVR!!!!!!

55 year old female

treatment 12 weeks Sovaldi/Olysio

genotype 1a

compensated cirrhosis

 

previous nonresponder to interferon/RIBA in 1998 and pegulated IFN/RIBA 2010

 

I still am having a hard time believing it! Thank you God!



__________________

Audrey

 

55 y/o, GT 1A, 1.4 million UI, cirrhosis, low platelets, enlarged spleen, high LFTs. Failed tx x2. 12 weeks Sovaldi/Olysio. Undetected end of treatment and 4 weeks after EOT!
bassetgirl


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I just got my 12 week after treatment viral load results: SVR!!!!!! I'm cured!!!!! I'm crying as I type this.

Gender:female
genotype 1a
compensated cirrhosis
treatment: 12 weeks Sovaldi/Olysio
VL at start 2 million

Comments: blood platelets have been around 60 since last spring, they are up to 72 as of yesterdays blood work. I am hoping that my liver function will continue to improve over time.

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 Female. When treated: age 63, gt 1a, compensated cirrhosis, platelets 67,S/O 12 week treatment,EOT July 30 2014

Oct. 23 2014 EOT + 12 SVR !!!!!! Thank you God and Medical Science.

Jan 19 2015  EOT + 24 results: still SVR
pl1952


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Hubby:

Age: 58 

Home: USA

Genotype: 1B

Stage: Fibroscan score 25 = cirrhosis

Regimen: Sovaldi & Olysio

Began treatment: 3/20/14

Ended treatment: 6/11/14

EOT+14 weeks: 9/23/14

Outcome:  SVR



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Me: 62 yr. old female, GT 1b, fibroscan 4.5; VL 650,975 as of 2/4/14;started Harvoni 3/6/15; SVR


Hubby: 59 yrs.; GT1b; fibroscan 25-cirrhotic; S/O for 12 weeks started tx 3/20/14; SVR56; fibroscan done 7-7-15 = 8.5
Peter M


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Age: 64

Home: USA, Pacific NW

Diagnosis: 1970s elevated liver enzymes 1980s NonA-NonB 1989 HCV

Genotype: 1B

HCV stage:  compensated F4

Regimen: Sovaldi and Olysio

Began treatment: April 11 2014

Ended treatment: July 3 2014

EOT +13 week test: October 3 2014

Outcome: SVR!!!!



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64 YO - HCV  45 years - GT 1b - F4  - starting VL 7,800,000 - AST 130 ALT 164  - started S/O 4-11-14 - week 2: - AST 37 -ALT 43 - wk 4 VL <40 - UND week 8, 12, eot, +4 +8 +12 SVR!!!  My Blog-Visit hepcstories.wordpress.com!
pizzacake


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Age: 62, 

Home: USA, Pacific NW

Diagnosis: 1971 "non-A and non-B hepatitis" (Sharing infected needles) 

Genotype: 1A

Fibrosure stage:  F3-F4

Regimen: Sofosbuvir, Ribavirin, and Interferon

Began treatment: June 24, 2014 

Ended treatment: September 17, 2014  Virus undetectable

 

 

 



-- Edited by pizzacake on Sunday 28th of September 2014 04:14:37 AM

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Age: 62, Lived with Hep C since 1971 (Sharing infected needles)

Home: USA, Pacific NW

Genotype: 1A

Fibrosure stage:  F3-F4

Begin 3-month treatment June 24: Sofosbuvir, Ribavirin, and Interferon

Born in the Year of the Dragon. 

 
suziq


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Hi

Most of my info is in my signature line.  But here it is again.

80 year old female with genotype 1a. Diagnosed in 1999.  Cirrotic-compensated

First and only treatment  18 weeks of Merck C-Worthy clinical trial with Riba 

Started Sept 2013  Finished Jan 2014 UND since Oct 2013 Declared SVR July 2014.

Have not started Merck clinical follow-up yet.  That should be interesting.

Called for appt for scan for HCC and the follow-up this week. (Sept 22 2014) 

Will post follow-up info when available.



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Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR
Dee Dee


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55 yr old female. 1a Q80k present. Treated w/ interferon - RIBA 6 months 2005. Relapse . 3/2014 started S/O waiting on EOT 12 weeks results. Posting results soon !

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G1a prior tx 2005 with peg & RIBA -quit due to bad side effects. Follow up visit showed it was back. Current tx Olysio/sovaldi 673,000 vl on 3/21/14. May 1st undetected vl. EOT 12 weeks undetected!
maddie


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Congratulations Sarah!  Wish you much happiness for all the wonderful hep c free years to come. 



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Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
smccune


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Interf/RIBA 24wks non cirrhotic 3a 54 yr old female.  SVR at 4wk still SVR at 12 wk post tx.  diagnosed 9/2011. treated 9/2013- 3/3014. Infected 8 /27/1986 from blood transfusion After 1st childs birth. Mother of 2 both negative.  Worked full-time during tx as industrial engineer 



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55 yo female.  Diagnosed 9/2011 Geno 3A.  Treatment delayed because of 9 Month antibiotic tx because of TB Positive test. Began tx 9/20/2013 Interf/Riba 24 wks.  Week 4, 8 undet. 1 year.......UNDETECTED!
Huey


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53 year ole male HCV Genotype 3a , now Psot-Tx taking sovaldi /riba for 24 weeks. VL was 5.8 mil on 7-5-13 , then "und" at 3.8 weeks of teatment. After test on 06/13/14 still und. Due to an adverse advent from a liver biopsy I was off meds 3 days then back on 7/29 I took my Last pill 08/10/14. and my 4-week post EOT VL test was done on 9/03/14, 9/8/14 SVR (Liver Stage  A2_F2)



-- Edited by Huey on Tuesday 9th of September 2014 01:19:22 AM

__________________

  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
Groupergetter


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63 year old male 1b, now cirrhotic. Relapsed 4 weeks post tx after 3rd try, 12 weeks of Sovaldi/Olysio. Increased arthritic and neuropathy symptoms. Hoping and praying my insurance will cover another round of tx.



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1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
Huey


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53 year ole male HCV Genotype 3a , now Psot-Tx taking sovaldi /riba for 24 weeks. VL was 5.8 mil on 7-5-13 , then "und" at 3.8 weeks of teatment. After test on 06/13/14 still und. Due to an adverse advent from a liver biopsy I was off meds 3 days then back on 7/29 I took my Last pill 08/10/14. and my 4-week post EOT VL test was done on 9/03/14, I am waiting for the results. will update then.,

__________________

  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
Kellie


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SVR - 2nd try

24 week tx - Incivik, Peg/Riba

Contracted 1980 - Minimal fibrosis - Will have 1 year post tx end of September.

Feeling good! No fatigue or muscle soreness! Still a little crazy from the Interferon

Another added bonus, I am more heat tolerant.



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HCV 1A 1980. Dual tx 2003 -UND at wk 11-discontinued due to severe depression

Started Triple 4/16/13 for 24 weeks

UND wk 4,6,8,12,17 & 24

E.O.T. 9/29/13

EOT + 12 weeks=SVR, and EOT +26 weeks=Cured!
maddie


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SVR with Sovaldi/Olysio x 12 weeks   Had hx of the virus for 32 years.  WAS GT1a, Tx naive with Q80K polymorphism   Not clear on stage when started tx, but hepascore indicated significant fibrosis. 



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Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
mallani


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SVR on 4th try. 48 weeks of Victrelis/Peg/Riba. Had HepC for 40+ years. Cirrhotic, now 71 years old. Geno 1b, IL29B CT. No symptoms before Rx- now back to normal after the effects of Interferon have gone.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
marktrux


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SVR on my 5th try. 12 weeks of Incivek and 48 weeks of Peg/Riba.



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KCCO

 

 
Tig


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57 YO, GT 1a, 35 years HCV+, Non cirrhotic, A2/F2-3, 28 weeks Peg Interferon, Ribavirin and Victrelis, treated x2 (null responder 1996)

SVR @EOT+21  April 2014



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Tig


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Before this thread gets populated with multiple posts, I'd like to make a suggestion. In order to keep this thread on topic, it might be wise to limit the content to the actual subject line as laid out by Mary, the original post. If you want to elaborate on something mentioned, do so in another thread. That will make reading this easier and it will stay on topic. Thanks!

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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JLynch30


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12 weeks solvaldi/rin/interferon

 male, 46, cirhosis

Undetected at week 2:  relapse at week 13.  

 

1a



-- Edited by JLynch30 on Thursday 4th of September 2014 01:25:55 AM

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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 
Gator Man


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Sovaldi/Olysio-no Riba, 12 weeks tx off label started on 1/6/14, compensated cirrhosis-liver biopsy, GT 1(b), 54 year old male, UND at 4 weeks, SVR 12, minimal sx-insomnia primarily.



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Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.
Dzdayscomin


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53 yr Male Finished 12 weeks tx 5/28/14 Sovaldi /Olysio off label, 6/12/14 undected 8/29/14 SVR GT1a

Cirrhotic



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
bassetgirl


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I thought it might be helpful to have a treatment outcome record on one thread. Tig suggested I start it in the post treatment section, so here it is.

It would be easier to read results if each person uses pretty much the same format: what drugs they used for treatment, duration of treatment, liver status (cirrhotic or non-cirrhotic), genotype, age, male/female, plus anything they feel was significant with their treatment.

Me: I finished 12 week treatment with Sovalfdi/Olysiio on July 30 and will have my 12 week  EOT viral load test Oct. 23; will post my outcome at that time. I am genotype 1a, compensated cirrhotic, 63 year old female with platelets around 65, and a liver tumor being monitored every 3 months with MRI. I am being treated at a liver transplant center/teaching hospital and was diagnosed with Hep C in January 2014, probably had it since 1977 and didn't know it.



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 Female. When treated: age 63, gt 1a, compensated cirrhosis, platelets 67,S/O 12 week treatment,EOT July 30 2014

Oct. 23 2014 EOT + 12 SVR !!!!!! Thank you God and Medical Science.

Jan 19 2015  EOT + 24 results: still SVR
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