Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> Clinical Trial Participants -> Last pill today!!
Post Info TOPIC: Last pill today!!
suziq


Senior Member

Status: Offline
Posts: 327
Date:
RE: Last pill today!!
Permalink  
 

Hi Marcy,

Congrats on finishing your trial!!!  Went in to my trial center yesterday for first follow-up appointment.  Had my first HCC scan as well.        I have been UND for a year now--SVR since July.  My coordinator said she had 25 on your trial and only 5 were on placebo.  I did ask about your enzymes going down.  She said that probably meant you were on meds BUT she is very cautious about telling HER trial participants  that it meant they were on the meds or UND.  However, she is very enthusiastic about Merck.  Like Malcolm said, Merck is not very  forthcoming with information on their trials. 

Glad you had few sides.  Think mine were caused by riba.  Just waiting to hear UND from you. 

SuziQ



__________________

Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR
Matt Chris


Guru

Status: Offline
Posts: 1782
Date:
Permalink  
 

Hey pep

Congrats are in order for you as well, hoping all go's well in your future and your full health returns.

matt



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
Milliganus


Senior Member

Status: Offline
Posts: 168
Date:
Permalink  
 

Pep wrote:

Took my last dose of S/O today also. Had my lab drawn and awaiting results. Good luck to both of us!!

 Fingers crossed for you too Pep!!



__________________

Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND
Milliganus


Senior Member

Status: Offline
Posts: 168
Date:
Permalink  
 

Since it was a blinded clinical trial, I couldn't see the viral load.  I should know in 1-2 weeks, however my liver enzymes went way down.



__________________

Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND
Dzdayscomin


Senior Member

Status: Offline
Posts: 471
Date:
Permalink  
 

Pep wrote:

Took my last dose of S/O today also. Had my lab drawn and awaiting results. Good luck to both of us!!

 Did you have any VL test during tx? Undected then ?



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
Pep


Member

Status: Offline
Posts: 9
Date:
Permalink  
 

Took my last dose of S/O today also. Had my lab drawn and awaiting results. Good luck to both of us!!



__________________

 

58 y/o female. DX 9/12, Geno 1, Began S/O treatment 7/8/14. No prior treatments. 
TazKat


Senior Member

Status: Offline
Posts: 479
Date:
Permalink  
 

yayyyy!! what a wonderful day!!!!! smilesmilesmilesmilesmile



__________________

TazKat Genotype 1A null responder x 3 riba & iterferon twice, relapsed from Incivek 2012 with only 12 weeks left to do. stage 4 mild cirrhosis 4/25/2014/ started sovaldi riba & interferon.. finished treatment 7/17/14  results 7/25  cleared..

 

 
Mugsy


Senior Member

Status: Offline
Posts: 172
Date:
Permalink  
 

Hooray! Must feel wonderful to take that last pill. Good job.



__________________

62 y/o F     Genotype 1b  for 40+ years    cirrhosis    Started Harvoni  on 11/23  for 12 weeks       UND  12/22/2014     Ended treatment on Feb 15th.

12 week's EOT viral load      <15 
Isiscat2011


Guru

Status: Offline
Posts: 1724
Date:
Permalink  
 

Well done, Marcy.  :)

Perhaps the C-EDGE results will be presented at the AASLD liver conference in Boston in November.   Anyone interested in the results from the C-WORTHY trial can click here:

http://www.mercknewsroom.com/news-release/corporate-news/mercks-investigational-chronic-hepatitis-c-combination-therapy-mk-5172mk



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
mallani


Guru

Status: Offline
Posts: 3398
Date:
Permalink  
 

Hi Marcy,

Congrats on getting to the end. I don't understand why Merck are so silent about this combo. They must have some C-EDGE results by now, so why don't they publish them?

From C-WORTHY, your SVR chances are >90%. Good luck.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Milliganus


Senior Member

Status: Offline
Posts: 168
Date:
Permalink  
 

Thanks everyone!  Whatever the outcome, I am super grateful to have been part of such a wonderful supportive group.  Only people who have walked in the same shoes as others can truly understand what they go thru.   SVR or not...it's all been a blessing.

Thanks again!



__________________

Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND
wmlj1960


Moderator

Status: Offline
Posts: 1559
Date:
Permalink  
 

Wow Marcy, that's great that you experienced almost no Sx's during Tx.

I hope Gator Man's Johnny Carson / Carnac performance turns out to be true. smile



__________________

60 yo, geno 1a, Dx 1994 HCV-HIV co-inf, Dx 2013 decompensated cirrhosis
Tx #1 - 24wks Sov+Riba /SOT 7-24-2014/UND@EOT/DETECTED@EOT+16 wks
Tx #2 - 24wks Harvoni /SOT 7-25-2015/UND@EOT,+12,+24,+52 = SVR

Mike

How To Create Your Signature / Forum Abbreviation Definitions

Support This Forum
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

Congratulations Marcy!



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Scruffy


Guru

Status: Offline
Posts: 500
Date:
Permalink  
 

Thats great and best wishes for you. 



__________________

Geno 1a null responder 2004 inter/riba   finished incivek,peg/riba 48 weeks May 17th 2014. undetect weeks 4-12-32.  EOT+7 undetect. EOT+24 SVR!!!!! EOT+!YEAR SVR!!!!
Groupergetter


Guru

Status: Offline
Posts: 796
Date:
Permalink  
 

Marcy,  I think you have the right attitude about this.  Being positive and thankful to get in this trial while being cautiously optimistic.  Hoping and praying you make it.    



__________________

1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
pl1952


Senior Member

Status: Offline
Posts: 236
Date:
Permalink  
 

Good luck Marcy!

 



__________________

Me: 62 yr. old female, GT 1b, fibroscan 4.5; VL 650,975 as of 2/4/14;started Harvoni 3/6/15; SVR


Hubby: 59 yrs.; GT1b; fibroscan 25-cirrhotic; S/O for 12 weeks started tx 3/20/14; SVR56; fibroscan done 7-7-15 = 8.5
Fireman Rob


Senior Member

Status: Offline
Posts: 334
Date:
Permalink  
 

Congrats Marcy,

 May this be the start of your HCV free life! That's great the meds treated you well. Good Luck!

-Rob



__________________

Age 33, Male. GT-1 for ten years. Diagnosed in March, 2014.

Treated with Sovaldi/Olysio: SVR 24 on February 16, 2015!
Dzdayscomin


Senior Member

Status: Offline
Posts: 471
Date:
Permalink  
 

Congrats Marcy, I pray that you will be free of C in no time....as said you have really supported others now It's your turn! 

Prayers to you

Duane



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
Matt Chris


Guru

Status: Offline
Posts: 1782
Date:
Permalink  
 

Hey Marcy

Congrats on making to the end of your trial, from here your body will take over and deal with any anomalies. Stay happy and healthy

matt 



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
Tig


Admin

Status: Offline
Posts: 9281
Date:
Permalink  
 

Hi Marcy,

I'm so happy for you! You've been a strong supporter for so many of us and have handled your own Tx so well. I'm so glad you avoided the severe SFX and will keep my fingers and toes crossed for your success! We are all rooting for you and wish you the very best!!! 

Tig



__________________

Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

Hep C FAQ   Lab Ref. Ranges  HCV Resistance

Signature Line Set Up/Abbreviations   Payment Assistance

 
Gator Man


Senior Member

Status: Offline
Posts: 442
Date:
Permalink  
 

We'll be cautiously optimistic as well! Good luck, Marcy! 

I'll perform a Johnny Carson/Carnac the Magnificent impersonation and say that the answer is that SVR is in your future!smile

 



-- Edited by Gator Man on Wednesday 1st of October 2014 05:19:40 PM

__________________

Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.
Milliganus


Senior Member

Status: Offline
Posts: 168
Date:
Permalink  
 

Going into the trial center today for my last pill.  This is the Merck C-Edge 1 pill, 2 drug combo.  I have to say the whole thing has been a breeze with almost no side effects.  I should know in a couple of weeks my VL.  Cautiously optimistic.  

 

 



__________________

Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> Clinical Trial Participants -> Last pill today!!
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.