Hep C Discussion Forum

Precisionbrown wrote:

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Hi friends, I decided to take a day or so off the harvoni and restart in another day. The water wagon is here. I have noticed that the water helps with some discomfort. I'm waiting for my test results to come back and I hope everyone else is getting better. Again thanks for the support! Precision

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 Huh? You can do that?

Canuck wrote:

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Jen 1,

Ya, that's about what I weigh lately, 112 -113 and I found it hard during treament and ever since after to reach/stay at115 - dunno why. Pudgiest I have ever been has been maybe 120-maybe 125 once or twice, I'd like to stay about 115.

I learned (very slow) about how good the water was for me on treatment (or anytime really). I could cure a headache with it, and i should have MADE sure (at all times) to keep my intake up, as it was one the main things that helped at all in making me feel better, and it helped my chronic constripation. When I felt worse, I was letting my water intake slip.

It is a hard thing to believe (or to want to do in my case) to have drink so much water - doesn't feel natural somehow, if you are not a water drinker normally. But is it a very good aid, a very important aid to your body just in transporting/pushing these potent drugs through to reach every cell of you and then helping your liver (via gut) and kidney flush out the metabolized waste products. It is unlikely anyone would ever do themselves any harm drinking a near gal a day of water, even a lightweight like me, and especially so when you have a very good reson(s) for doing so, like being on these drugs.

It's good you have settled into some kind of sure-fire "system" to count/measure/remind yourslef to drink the water - that was also key for me - to have a constant "visual" reminder, and a "routine" and system for same.

Even right after treatment when I was cutting back on water, I could a penality for it. Even today I have learned a good lesson from treatment days and I have since re-learned to appreciate and drink more water! I am kinda enjoying water more now. :)

Hmph, sorry they gave you that drug re-order glitch scare - not needed. But glad you are not feeling too bad overall. 

Sept 28 is pretty close to your 4 week mark, those labs and visit will come soon enough - and we all bet the results will be a very good and welcome reward for you. C.

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Thanks Canuck. I just saw you're in Canada. Went to Niagara Falls for the first time last week....Beautiful Canadian side, of course :).  Did all the touristy stuff. So much fun!

Canuck wrote:

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Jen1,

How goes it (all in all)? You must be due for a 4 week lab visit next week? How is it feeling, and how much trouble are you having getting the water in? C.

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 Hi Canuck,

Thanks for asking. I start month 2 next week but my doctor is away until Sept 28th so I have to wait till then to see her. Had some moments of terror today when I called to arrange for month 2 with the specialty pharmacy (my insurance didn't allow me to get all three months worth of pills at the start) and was told there was some issue.  It finally DID get resolved but that was really not what I wanted to hear!

I had been very scared about possible side effects before I started. I'm more of a vitamin/supplement person than a drug person - although I stopped everything for these 3 months though I probably didn't really need to.  I've really felt normal and OK.  I have a big 32 ounce water bottle which I'm focused on filling up a few times a day. I found with the smaller ones, I'd lose track of how many times I filled it. I only weigh 113 so I'm drinking a lot more than half my body weight in ounces but I figured it can't hurt.  

My doctor had very casually mentioned STAY HYDRATED when I asked what I should do on Harvoni. I know myself and I know for sure  I'd NEVER be drinking so much without the guidance of people here. ( I would have assumed "stay hydrated" meant drinking waaay less.)  I have no doubt it's helped me feel so good and I'm very grateful!!

Best,

Jenny

Hi precision,

Glad you have arrived here, but sorry for how you have been feeling. First 4 weeks can be the hardest, some find some of these things do begin to level out later in the course of treatment. (Dilute them!)

All the things which you mentioned icky stomache, perhaps some wgt loss, sometimes night sweats, maybe "coughy"/achey, and perhaps fluctuating BP could all have to do with this inner war you are waging with the virus. Your body is in full-out war mode against the virus, and will win. I have no idea if you had any prior tendency to blood pressure fluctuatons before, or if you have ever been on BP meds, but keep an eye on things (write your BP's down and show to doc) - do you have a hot line to you doc offices to help for questions on the phone? That would be nice, if you are feeling too worried or rough. Night sweats can be part of the battle and could also be of other hormonal issues if you of the age for those. Some things may feel flu-ish, so just be sure you are not having a flu as well!

You are doing the right things, if you are not feeling well, treat yourself as well as you possibly can, rest, try to drink LOTS of water, and eat small nourishing healthy foods as you can. If you have to book off, do so, just see how things go. I hope you will turn a corner soon and these unpleasant things lessen for you.

You must be due for a 4 week blood draw and doc visit? If you do not seek advice from your doc prior, be sure to mention all of these symptoms when you do see him (or her).

Like you, and me and Jen1 (and many others) we may not be used to, or enjoy having to drink this much water!!! But, I cannot stress HOW important it is. Strive for that gal of water per day - really important and may prevent "sides" or bad feelings from occurring.

As someone wisely mentioned here, you could try making sure you take your Harvoni with food. I do not exactly know exactly what the stomache issue is, or how/when it affects you, but it might possibly help to take harvoni with food versus on an empty stomach (AND, of course, with LOTS of water!) all day long! If it is nausea you are having, then try steeping up some weak fresh ginger tea - (to taste, sweet or not) and sip little bits of it, hot or chilled - said to help settle a quesey stomache. Keep your diet light, perhaps more frequent, especially if they are smaller meals, nothing too heavy/fatty, easy to digest.

When you feel up to it, try to write up a signature line with your particular stats - age, sex, state, GT (1a or 1b?), year HCV likely contracted, year diagnosed (1992?), pre-treatment VL, ALT, AST, Fscore (F 0 thru to F 4?) determined by fibroscan/biopsy or other blood tests?, if you have had an abd U/S, things like that. state length of treatment (Harvoni 12 weeks) and SOT date, and EOT.

These sig lines (like you see we all try to sport) are so helpful for conversation purposes.

Some where you said something like that you were around a million VL? and that "it was borderline"? not quite sure what you meant, any "detectable" load means you have the virus that needs tretament, how high or low it is does not really indicate how "sick" a person may bes, you still have the virus with a higher or lower load - only dif really is in perhaps length of treatment or choice of treatment, with higher loads over 6 million they may not give you a "short" course of tretament, and/or may choose a regime best suited to you, someimes a triple regime versus a double drug regime.

Fire away if you have questions, or just want to share, we can all try to assist, where we can, someone is always home here. C. 

Is it possible that as the HCV clears up it could cause hyper-tension to decrease? I've taken Lisinopril for high BP for several years and now my regular dose seems to be too much. My BP is much lower in the last couple of days. I suppose I'll see if the trend continues and take it from there. I halved the amount I normally take last night and my BP is lower end of normal today.

I'm working hard to drink that much water consistently. Doesn't come naturally to me at all. I hope you feel better, Gloria. What you're experiencing doesn't sound like fun!

Yeah sure, I'm a working musician but I took awhile

off because of the Harvoni situation. Anyway, this is my 4th week and I'm feeling a little discomfor. Coughing, achey and some sweats but it's really nice to see you guys being so supportive!

 I'm on a 12 week run with Harvoni. I was diagnosed with hep C in 1992 and turned down the other offer because I had no time to feel wose on interfurin.

my count was a million which I was told was borderline? Well I'm starting to take longer naps than usual and I've noticed my blood pressure is on the higher side and fluctuating.

well that's about it. I was just offered a gig in 2 weeks but I think I'm going to turn it down only because there's no way I can produce 100% and that's the only way I'll go back to working playing music.

 I really appreciate the support here.

Gloria welcome.

So as not to get lost in the crowd, how about telling us a bit about yourself in the New Members area? Love to hear more about you and we are very happy you found us.

JimmyK

I've been drinking 80-90 ounces of water a day (sometimes even more) as people on this board suggested. It seems to have helped me have no obvious side effects. I'm also taking the pill on a full stomach. Hard to know which thing if either has made a difference but I'm planning to continue with this pattern 

Polo,

Ah, your Club Zero chaise lounge chair, special, just fer you. Just relax, stretch out, turn over, we'll summon the masseuse for you. : )

HepCFriends --- Thanks for all the congrats, support, well wishes for my UND and Club Zero status.

I am happy to report that my neck crick is much improved this morning, hooray! Another day of laying low with TLC, hot/cold packs and Tylenol should do the trick to boot the crick.

Outstanding!! I'm very pleased, you deserve this great news. Congratulations!!

CONGRATULATIONS   It's a great club to be a member Of! 45 years is a long time to house the dragon, but it looks like he found the eviction notice. Your kicking it's butt.   RC

The pic below is you giving the dragon his eviction notice!

-- Edited by robertsamx on Friday 8th of September 2017 09:30:22 PM

This just in!! I'm a member of the Club Zero!!!! It took me ~45 years to get in and its going to be worth it!!

Flexeril is not on this list:  https://www.drugs.com/interactions-check.php?drug_list=758-386,3567-16903

Nor is it mentioned in:

https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/harvoni/harvoni_pi.pdf  (section 7).

You could also phone your pharmacy and ask them to double check for you.

We are not doctors, and do not know every nuance of you and any other conditions or things you may have going on, so, it is never safe to tell a person - ya just go ahead -  it will have to be your call or your docs call (or perhaps based on pharmacy advice) - but from what we can see here, Flexeril (at face value) is not showing up as having negative interactions with Harvoni.

https://www.drugs.com/flexeril.html

If it were me (and I was in pain, and had no access to my doc for days) I'd try asking a pharmcist and if all seems OK, then i would (but that's just me).

Can't wait for your VL results to come in! : )  C.

Thanks everyone for the congrats! I'm still waiting for VL results--

I do have an issue here, I have had a major crick/strain in my neck now for 4 days! I took Tylenol for a couple of days, and it is slightly better, yet I need something more to knock it out. It is something I get a couple of times per year and I have 'flexeril" to take for it. However, I wanted to check to make sure no interaction with Harvoni. I called the doctor office and they are not available until Monday. Should I check with a pharmacist? I'm trying to decide what to do. When this happens I usually take 5 mg at bedtime and next day its gone.

That's excellent! Nice liver enzymes. They tell me treatment is working

Yay! PS-That is exciting news!  So happy for you!!

Hello everyone -- my CBC and Metabolic panel results are in, and still waiting on VL results, but it is looking quite promising. ALL of my blood work is in the normal range even protein levels, platelets, ALT, AST for the first time in years. I'm stoked and giving blowback to the dragon at this point. Hopefully I will hear the good news on VL soon.

4 weeks AST 34 and ALT 31, waiting for VL results.

Hey Saluda, 

Just got back from out of town. Sheesh, ya close eyes fer jes a minute and darn it all if good news doesn't just happen! I always seem to arrive a wee bit late for these parties.

Congrats an a beautiful 4 week result. A lovely UND, and ho-li-cow, look at your crashed ALT and AST (hee hee).

Very good news, all round, a good looking GB site, a liver thanking you, and your nice gal to celebrate anniversaries and other good fortunes with! Happy 30th and Happy 4 week. A big day is right! Very happy for you. C.

Good deal, great numbers