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Hep C Discussion Forum -> General Discussion -> Anti HCV ab positive. feeling anxious
Post Info TOPIC: Anti HCV ab positive. feeling anxious
Tig


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RE: Anti HCV ab positive. feeling anxious
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Hello Bashar,

I'm so glad you found our forum and that we all got the opportunity to meet you! I'm happy we were able to help you through this stressful time. It's nice to be able to provide such happy news too! 

Congratulations on your wedding and I hope you have a wonderful honeymoon!!! Good luck to you both!

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Bashar


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Dear all,

 I can't explain myself..............This is such a good news to celebrate. Wish we will go for our honeymoon as early.smilesmilesmile

Plz pray for us. I will never forget the way you support  me here.



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Cinnamon Girl


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Hello Bashar,

I`ve just had a look at your wife`s results and I agree with everything that Tig said.  The most important piece of information there is the bit that says `HCV-Hepatitis C Viral Load (Quantitive)..Target Not Detected`

So your wife does not have Hep C, what excellent news for you both!!  Now you have something else to celebrate...I`m very pleased things have turned out so well for you!!  smile



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
LC


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Yay!  Now you can celebrate! smile



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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Tig


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Hello Bashar,

I had to read the results several times and I see a few different pieces of information. First and biggest is that the PCR report indicates there is no detectable HCV virus. That's great news!! She does not have an active HCV infection, yeah! She does show positive antibodies for HCV, this tells me that at some time in her life, she was exposed to the virus but her own immune system was able to fight the virus off by itself. People that test positive for HCV antibodies will test positive for the rest of their life and is nothing to worry about. Only 20-30% of the people exposed to HCV are able to fight off the virus in this manner! She's very fortunate to have beaten the virus like this!

She tested 19 on the ALT blood test, this is a liver enzyme test, when elevated it can indicate liver disease or damage. Her test is normal, no indication of problems.

I see no problems Bashar! No detectable Hepatitis C, and a normal liver enzyme (ALT). This is great news! Along with the good biopsy report earlier this week, she has been very fortunate! I wish you continued good luck!

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Bashar


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Dear all,

I get the HCV blood test result today. Here I attach these for your consideration.

Thanks



-- Edited by Bashar on Saturday 8th of November 2014 09:36:08 AM

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Tig


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Hello Bashar,

Mallani was referring to the benign biopsy results from your wife's breast lump. The fibroadenoma was benign, so no further cancer fear is warranted. The tests you listed on your last post are the diagnostic blood tests associated with HCV. Also looks like she had an abdominal ultrasound that showed no abnormalities (normal). That's excellent news! Next is to have the HCV blood tests completed. Good luck!

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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LC


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She will need treatment if a viral load is detected. The good news is Harvoni should be available much cheaper in Bangladash. It's supposed to go for about $10 a pill in India, and it's $1,000 in the US.

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Bashar


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Dear mallani

It is such a relief at this stage.......... You mean no further treatment...for what? is it for the lump or Hep C? Are these following test for Viral Load?

HCV Genotyping

HCV RNA Quantitative (RTPCR)

HCV lgG Antibody

ALT (SGPT)

And FYI  Ultrasonogram for hepatobiliary system & pancreas result also came normal.

Thanks a lot for your support.

Thanks Cinnamon Girl & LC. We feel lucky enough having well wishers like you.



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Cinnamon Girl


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That is such excellent news, Bashar, I`m so happy for you and your wife! 

What a big relief this must be for you both, and now you can both relax for a while before moving on to the next step of having her viral load tested.  Thanks for sharing this good news with us!

Take care, and do keep in touch!  smile

Ps - We are very lucky to have Malcolm (mallani) with us here to interpret your wife`s biopsy report!



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
LC


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mallani wrote:

 a benign breast tumour

 Yay Bashar!



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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
mallani


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Hi Bashar,

Great news! Just a fibroadenoma, a benign breast tumour. No cancer, and no further treatment is required.

When your wife's recovered, get the VL test just to make sure.

Always good to hear good news! Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Bashar


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Dear All

I am so grateful to all of you that you put your valuable opinion here. It may not the stage to worry too much but I can't.

I can understand a very little from other post around.  I am sharing the biopsy report for your consideration. We will meet the surgeon to show the report tomorrow.

Thanks

 



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mallani


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Hi Bashar,

We are assuming the 'lumpectomy' was for your wife's breast mass. If the surgeon just did a lumpectomy, he must have been convinced it was not a serious tumour. I assume he would have checked the lymph nodes in the axilla (armpit) as well. This is all that's important right now. I hope the Pathology report is OK.

When all that is sorted out, the HCV VL test can be done. Your treatment options in Bangadesh are a different subject, and we can discuss that with you later (if your wife has chronic HCV). Best of luck.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
beingsassy


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As several people here have already stated, try not to worry about the hep. If your wife does need treatment, there are newer meds with very high success rates. But first more tests are needed. She may not need any treatment depending on if it is chronic or not. As for the lump, I have no idea. The Hep is not a death sentence. Look around the different posts on this forum which may answer many questions or just ask. We are here to support and help one another.



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Tig


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Hello Bashar,

We are all hoping for the best news for you and your wife. I am praying for you both. Please let us know when you hear anything. I hope your wife is resting comfortably following the lumpectomy (surgery). Give her our best wishes for a fast recovery.

If and when you have any laboratory reports regarding your wife's HCV status, you can share them with us here and we will do our best to provide informed opinions. There are many circumstances involved in making these decisions. I'm not sure what options are available in Bangladesh, but we'll help you understand the decisions and options you are provided by her doctor. Keep your spirits up and try to stay positive. You are among friends here! Good luck...

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Bashar


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Hi LC,

Thanks again for comment here. I dont know more on Hep C. My wife recently tested Hep C positive/ reactive. We also wait for the further investigation results such as genotype, RNA quantitative, IgG Antibody & ALT.



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LC


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I meant if she has Hepatitis C, that can usually be treated faster these days with an all oral regime. As to the lump I can't say of course. Hopefully it's fluid buildup or something minor.

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Bashar


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Dear LC,

Sorry, I can't get your point. Are your talking about the lump.

I am not understand the term "Interferon free treatment also.

Thanks 



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LC


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They can usually knock it out fairly quickly and painlessly now days. It just takes awhile to get the meds sometimes. Please try to hold out for an Interferon free treatment if she is able to.

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Bashar


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Dear Cinnamon girl,

Thanks for feeling my situation.

Some people made us anxious seriously. I couldn't share this matter anyone of my surrounding. Not even with my wife properly.  This forum is only the place where I share.

I will go for the biopsy report after 2 hours from now. Plz pray for us as we will be strong enough to handle whatever it comes.

Let us hope for the best.



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Cinnamon Girl


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Hello again Bashar,

Do let us know the result of your wife`s biopsy, and I`m hoping it will be good news.  It must be such a worrying time for you and your wife right now so just try to take it step by step as you move forwards.

You`ll get through this, just stay strong...I`ll be thinking of you today.  smile

 

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Bashar


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Dear Cinnamon girl & Isiscat,

Thanks a lot for your comment here. Thanks to almighty as my wife got a successful lump surgery on 4th Nov. That lump is now send for biopsy. Today I will get that result.

Have a good day.



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AB
Isiscat2011


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Hang in there, Bashar.  You and your wife will soon have more information.  Whatever happens you will be able to deal with it together.  smile



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Cinnamon Girl


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Hi Bashir, just wanted to wish you and your wife the best of luck with her test results! 

As Malcolm said, try not to worry too much at this point, wait and see whether the HCV RNA Quantitative PCR test shows that your wife has an active infection or not, and then if she has you`ll be able to discuss her best options for treatment.

Keep in touch and let us know, and again, best of luck! 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Bashar


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Hi mallani,

Thanks. Hope for the best.



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mallani


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Hi Bashar,

The test is positive for the HepC antibody, but at a low level.

The new tests will sort out your problems. If the HCV RNA Quantitative test shows a Viral Load, you will have the Genotype as well. Let us know the results.

Don't be concerned at this stage. Cheers from Australia.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Bashar


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Hi mallani,

Thanks for your reply. Yes , you are right about the sample & cutoff rate (attach report image FYI).

We met the prof. at 30th Oct and he gave the following test:

Ultrasonogram for hepatobiliary system & pancreas.

& blood test for

hepatitis panel-2

HCV Genotyping

HCV RNA Quantitative (RTPCR)

HCV lgG Antibody

ALT (SGPT)

We give the blood samples and have to wait for 12 days for the result ( though sample will diagnosis in Dilli, India).

We highly desire your opinion.

Thanks again.

 

 

 



-- Edited by Bashar on Sunday 2nd of November 2014 08:13:11 AM

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mallani


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Hi Bashar,

We need more information. The antibody tests are complex, and vary depending on the type of assay. I think you are referring to the Signal/Cutoff ratio (SCo) which can be 1.00. It seems your wife may have a SCo of 2.69%.

Is it possible to scan and post the report, then we can be of more help. These are EIA assays, or may be CIA.

If you're worried, the doctor will do a PCR test to check the Viral Load.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Bashar


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Hi,

This is Bashar from Dhaka, Bangladesh. This is about my wife as she got test results of anti HCV ab sample rate 2.69 & cutoff rate 1.00. It came out when I took her into a doctor for feeling a lump in he breast. The doctor refer her to a prof. of gastroliver. I take the appointment of that prof. I feel very anxious though I know a little about it. Plz reply what the test results means. 

Thanks.



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